Regulation and function of autophagy during cell survival and cell death.

scientific article published on June 2012

Regulation and function of autophagy during cell survival and cell death. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/CSHPERSPECT.A008813
P932PMC publication ID3367545
P698PubMed publication ID22661635
P5875ResearchGate publication ID225095717

P50authorBhupendra ShravageQ82239866
P2093author name stringGautam Das
Eric H Baehrecke
P2860cites workPINK1 is selectively stabilized on impaired mitochondria to activate ParkinQ21145802
Nix is a selective autophagy receptor for mitochondrial clearanceQ22001532
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting proteinQ22003920
ei24, a p53 response gene involved in growth suppression and apoptosisQ22010923
ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell deathQ24296645
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acidsQ24306330
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein AlfyQ24307759
Ambra1 regulates autophagy and development of the nervous systemQ24313508
A role for NBR1 in autophagosomal degradation of ubiquitinated substratesQ24316135
Parkin is recruited selectively to impaired mitochondria and promotes their autophagyQ24317471
Network organization of the human autophagy systemQ24324004
Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanismQ24329236
AMPK phosphorylation of raptor mediates a metabolic checkpointQ24329244
Inhibition of macroautophagy triggers apoptosisQ24338482
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressorQ24569647
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy geneQ24617547
Autophagy suppresses tumorigenesis through elimination of p62Q24650670
Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell deathQ24672925
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathwayQ24678032
Cytolysomes and mitochondrial degenerationQ24683054
Cytoplasmic components in hepatic cell lysosomesQ24683078
Tor-mediated induction of autophagy via an Apg1 protein kinase complexQ24685670
TOR signaling in growth and metabolismQ27860757
TSC2 mediates cellular energy response to control cell growth and survivalQ27860970
The consensus coding sequences of human breast and colorectal cancersQ27861035
Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85pQ27931717
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiaeQ27933914
Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeastQ27934020
Developmental cell death: morphological diversity and multiple mechanismsQ37922145
Autophagy and cancerQ37967998
Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survivalQ39585761
A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditionsQ39680852
OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteinsQ39747108
Autophagy gene-dependent clearance of apoptotic cells during embryonic developmentQ40160979
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.Q40239763
hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinaseQ40392574
Steroid regulation of midgut cell death during Drosophila developmentQ40631448
Activation of autophagy during cell death requires the engulfment receptor DraperQ41485538
Growth arrest and autophagy are required for salivary gland cell degradation in DrosophilaQ41913649
Autophagy-deficient mice develop multiple liver tumorsQ42099409
Autophagy in aging, disease and death: the true identity of a cell death impostorQ42609173
The mitochondrial permeability transition initiates autophagy in rat hepatocytes.Q43711895
The morphology of various types of cell death in prenatal tissuesQ44016309
Tissue-specific gene expression and ecdysone-regulated genomic networks in DrosophilaQ44507969
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult DrosophilaQ46506998
Autophagy regulates ageing in C. elegans.Q47069281
Steroid regulation of autophagic programmed cell death during developmentQ47071085
Autophagy promotes caspase-dependent cell death during Drosophila developmentQ47072768
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagyQ50537316
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy.Q51670090
Autophagy gene disruption reveals a non-vacuolar cell death pathway in Dictyostelium.Q52087662
Steroid regulated programmed cell death during Drosophila metamorphosis.Q52191726
Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.Q53658652
AMP-activated Protein Kinase and the Regulation of Autophagic ProteolysisQ56777095
Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideumQ73100649
Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinaseQ77195340
A ubiquitin-like system mediates protein lipidationQ27934137
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiaeQ27935838
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagyQ27936161
Atg32 is a mitochondrial protein that confers selectivity during mitophagyQ27936726
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagyQ27937577
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin proteaseQ27938863
Induction of autophagy and inhibition of tumorigenesis by beclin 1Q28131718
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagyQ28131727
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
Loss of autophagy in the central nervous system causes neurodegeneration in miceQ28131804
Molecular dissection of autophagy: two ubiquitin-like systemsQ28206420
Selective autophagy mediated by autophagic adapter proteinsQ28301940
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Q28506431
Studies on the mechanisms of autophagy: formation of the autophagic vacuoleQ28565520
SNARE proteins are required for macroautophagyQ28742152
Autophagy: renovation of cells and tissuesQ29547206
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell deathQ29547297
Autophagy regulates lipid metabolismQ29547421
The role of autophagy during the early neonatal starvation periodQ29547489
Autophagy genes are essential for dauer development and life-span extension in C. elegansQ29614180
Functions of lysosomesQ29614182
Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathwayQ29614186
Plasma membrane contributes to the formation of pre-autophagosomal structuresQ29614494
Mitochondria supply membranes for autophagosome biogenesis during starvationQ29614495
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulumQ29614500
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagyQ29615616
DRAM, a p53-induced modulator of autophagy, is critical for apoptosisQ29616308
Role and regulation of starvation-induced autophagy in the Drosophila fat bodyQ29617035
Isolation of autophagocytosis mutants of Saccharomyces cerevisiaeQ29617037
Autophagy in cell death: an innocent convict?Q29617604
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesisQ29617725
A Unified Nomenclature for Yeast Autophagy-Related GenesQ29618950
Termination of autophagy and reformation of lysosomes regulated by mTORQ29619817
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8Q29620200
Pancreatic cancers require autophagy for tumor growthQ29620331
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genesQ29620366
Control of autophagy initiation by phosphoinositide 3-phosphatase JumpyQ30489519
Starvation activates MAP kinase through the muscarinic acetylcholine pathway in Caenorhabditis elegans pharynxQ30524677
Cellular differentiation in the kidneys of newborn mice studies with the electron microscope.Q31162064
The association of AMPK with ULK1 regulates autophagyQ33745164
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.Q34063643
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesisQ34083172
Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formationQ34108934
C. elegans screen identifies autophagy genes specific to multicellular organismsQ34120920
Distinct death mechanisms in Drosophila developmentQ34361484
Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathwayQ34384803
Autophagic programmed cell death by selective catalase degradationQ34596715
Autophagy in immunity and cell-autonomous defense against intracellular microbesQ34673845
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenanceQ34681351
Autophagy revisited: a conversation with Christian de DuveQ34787821
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesisQ35128818
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver functionQ35750935
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvationQ35946374
Autophagy in metazoans: cell survival in the land of plentyQ36146937
Autophagy: dual roles in life and death?Q36146947
Autophagy and neuronal cell death in neurological disordersQ36329444
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.Q36660687
Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesisQ36890091
Autophagy and aging: keeping that old broom workingQ37321185
Autophagy in Drosophila melanogasterQ37336163
Autophagy, not apoptosis, is essential for midgut cell death in DrosophilaQ37438206
Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagyQ37460333
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexesQ37606853
Molecular mechanism and physiological role of pexophagyQ37677226
Protein misfolding disorders and macroautophagyQ37810685
Chemical modulators of autophagy as biological probes and potential therapeuticsQ37821750
Biogenesis and cargo selectivity of autophagosomesQ37872765
P433issue6
P921main subjectautophagyQ288322
cell deathQ2383867
P577publication date2012-06-01
P1433published inCold Spring Harbor Perspectives in BiologyQ3927509
P1476titleRegulation and function of autophagy during cell survival and cell death
P478volume4

Reverse relations

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