Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria

scientific article published on 15 June 2012

Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3109/1040841X.2012.691460
P932PMC publication ID4086240
P698PubMed publication ID22697133

P50authorZhi-Qing HuQ114884022
P2093author name stringWei-Hua Zhao
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Characterization of two plasmid-encoded cefotaximases found in clinical Escherichia coli isolates: CTX-M-65 and a novel enzyme, CTX-M-87.Q44651865
A novel extended-spectrum beta-lactamase CTX-M-23 with a P167T substitution in the active-site omega loop associated with ceftazidime resistanceQ44939657
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New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from BulgariaQ41774142
CTX-M-10 linked to a phage-related element is widely disseminated among Enterobacteriaceae in a Spanish hospitalQ41811129
Novel complex class 1 integron bearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 geneQ41882603
Prevalence of CTX-M beta-lactamases in Philadelphia, PennsylvaniaQ41931363
Complete nucleotide sequence of plasmid pTN48, encoding the CTX-M-14 extended-spectrum β-lactamase from an Escherichia coli O102-ST405 strainQ42047074
Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15.Q42111230
High prevalence of ST131 isolates producing CTX-M-15 and CTX-M-14 among extended-spectrum-beta-lactamase-producing Escherichia coli isolates from CanadaQ42111425
Detection of CTX-M-15 and CTX-M-33, a novel variant of CTX-M-15, in clinical Escherichia coli isolates in Greece.Q54448255
Novel plasmid-mediated CTX-M-8 subgroup extended-spectrum beta-lactamase (CTX-M-40) isolated in the UK.Q54465411
Prevalence, microbiology, and clinical characteristics of extended-spectrum beta-lactamase-producing Enterobacter spp., Serratia marcescens, Citrobacter freundii, and Morganella morganii in KoreaQ57212092
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First description of CTX-M-15-producing Klebsiella pneumoniae in TurkeyQ73677522
CTX-M extended-spectrum beta-lactamase arrives in the UKQ78871915
Diversity of genetic environment of bla(CTX-M) genesQ80068219
Characterization of CTX-M-22 and TEM-141 Encoded by a single plasmid from a clinical isolate of Enterobacter cloacae in ChinaQ81325586
Osteomyelitis associated to CTX-M-15-producing Aeromonas hydrophila: first description in the literatureQ84045915
Predominance of CTX-M-type extended-spectrum beta-lactamase genes among enterobacterial isolates from outpatients in BrazilQ84549341
Wide dissemination of multidrug-resistant Shigella isolates in ChinaQ84806742
Sequence of the gene encoding a plasmid-mediated cefotaxime-hydrolyzing class A beta-lactamase (CTX-M-4): involvement of serine 237 in cephalosporin hydrolysisQ33696142
Occurrence of CTX-M-3, CTX-M-15, CTX-M-14, and CTX-M-9 extended-spectrum beta-lactamases in Enterobacteriaceae clinical isolates in KoreaQ33722071
Nosocomial outbreak caused by Salmonella enterica serotype Livingstone producing CTX-M-27 extended-spectrum beta-lactamase in a neonatal unit in Sousse, Tunisia.Q33752900
Identification of a progenitor of the CTX-M-9 group of extended-spectrum beta-lactamases from Kluyvera georgiana isolated in Guyana.Q33769980
Identification of CTX-M-14 {beta}-lactamase in a Salmonella enterica serovar enteritidis isolate from JapanQ33836539
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Countrywide spread of community- and hospital-acquired extended-spectrum beta-lactamase (CTX-M-15)-producing Enterobacteriaceae in LebanonQ33884893
ISEcp1-mediated transposition and homologous recombination can explain the context of bla(CTX-M-62) linked to qnrB2Q33962875
Dissemination of CTX-M-3 and CMY-2 beta-lactamases among clinical isolates of Escherichia coli in southern TaiwanQ33970463
Identification of CTX-M-14 extended-spectrum beta-lactamase in clinical isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in KoreaQ33973766
A novel CTX-M beta-lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceae isolated in BrazilQ33980082
Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from KenyaQ33982586
Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240-->GlyQ33982717
CTX-M-type extended-spectrum beta-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loopQ33983530
Uniform nomenclature for bacterial plasmids: a proposalQ34071270
Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in PolandQ34104447
Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M typesQ34112598
High-level resistance to ceftazidime conferred by a novel enzyme, CTX-M-32, derived from CTX-M-1 through a single Asp240-Gly substitutionQ34139107
IncI1 plasmid carrying extended-spectrum-beta-lactamase gene blaCTX-M-1 in Salmonella enterica isolates from poultry and humans in France, 2003 to 2008.Q34151202
Infections caused by Kluyvera species in humansQ34350409
PCR classification of CTX-M-type beta-lactamase genes identified in clinically isolated gram-negative bacilli in Japan.Q34351969
Integrons: agents of bacterial evolution.Q34569146
Vibrio cholerae InV117, a class 1 integron harboring aac(6')-Ib and blaCTX-M-2, is linked to transposition genes.Q34648755
Chromosome-encoded AmpC and CTX-M extended-spectrum β-lactamases in clinical isolates of Proteus mirabilis from KoreaQ34737727
CTX-M-93, a CTX-M variant lacking penicillin hydrolytic activityQ34932847
Growing group of extended-spectrum beta-lactamases: the CTX-M enzymesQ35006613
Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli.Q35119621
Molecular characterization and antimicrobial susceptibility testing of Escherichia coli isolates from patients with urinary tract infections in 20 Chinese hospitalsQ35140054
Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase geneQ35685430
Extended-spectrum beta-lactamases in enterobacteriaceae in Buenos Aires, Argentina, public hospitalsQ35685785
CTX-M-35 extended-spectrum beta-lactamase conferring ceftazidime resistance in Citrobacter koseri.Q35748347
Comparative analysis of IncHI2 plasmids carrying blaCTX-M-2 or blaCTX-M-9 from Escherichia coli and Salmonella enterica strains isolated from poultry and humansQ36295488
ISCR elements: novel gene-capturing systems of the 21st century?Q36499667
Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in BrazilQ36593879
Characterization of extended-spectrum-beta-lactamase (CTX-M-15)-producing strains of Salmonella enterica isolated in France and SenegalQ45052519
Detection and characterization of extended-spectrum beta-lactamases among bloodstream isolates of Enterobacter spp. in Hong Kong, 2000-2002.Q45244902
Description of In116, the first blaCTX-M-2-containing complex class 1 integron found in Morganella morganii isolates from Buenos Aires, Argentina.Q45295749
Phenotypic and molecular characterization of two novel CTX-M enzymes carried by Klebsiella pneumoniaeQ45840163
Phenotypic and molecular characterization of a novel beta-lactamase carried by Klebsiella pneumoniae, CTX-M-72, derived from CTX-M-3.Q45933496
Extended-spectrum {beta}-lactamases and AmpC {beta}-lactamases in ceftiofur-resistant Salmonella enterica isolates from food and livestock obtained in Germany during 2003-07.Q45994003
Molecular epidemiology and antimicrobial susceptibility of extended- and broad-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated in PortugalQ46094500
Characterization of Salmonella enterica isolates from infants and toddlers in Wuhan, ChinaQ46264520
Plasmid-borne armA methylase gene, together with blaCTX-M-15 and blaTEM-1, in a Klebsiella oxytoca isolate from ChinaQ46352636
Emergence of imipenem resistance in clinical Escherichia coli during therapyQ46385100
Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type beta-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005--the new 'MRSAs'?Q46454793
Occurrence and molecular analysis of extended-spectrum {beta}-lactamase-producing Proteus mirabilis in Hong Kong, 1999-2002.Q46460989
Phenotypic and molecular characterization of 5 novel CTX-M enzymes carried by Klebsiella pneumoniae and Escherichia coliQ46794517
Prevalence of extended-spectrum beta-lactamases in Proteus mirabilis in a Taiwanese university hospital, 1999 to 2005: identification of a novel CTX-M enzyme (CTX-M-66).Q46969155
Spread of bla(CTX-M-type) and bla(PER-2) beta-lactamase genes in clinical isolates from Bolivian hospitalsQ46971053
Resistance of strains producing extended-spectrum beta-lactamases and genotype distribution in ChinaQ46988185
Variation in the genetic environments of bla(CTX-M-15) in Escherichia coli from the faeces of travellers returning to the United KingdomQ47591521
Prevalence and mechanisms of cephalosporin resistance in Enterobacteriaceae in London and South-East EnglandQ47595558
Molecular epidemiology of fluoroquinolone-resistant ST131 Escherichia coli producing CTX-M extended-spectrum beta-lactamases in nursing homes in Belfast, UK.Q47598652
Two novel plasmid-mediated cefotaxime-hydrolyzing beta-lactamases (CTX-M-5 and CTX-M-6) from Salmonella typhimuriumQ48021937
Characterization of IncF plasmids carrying the blaCTX-M-14 gene in clinical isolates of Escherichia coli from KoreaQ48059434
Complete sequencing of the FII plasmid pHK01, encoding CTX-M-14, and molecular analysis of its variants among Escherichia coli from Hong KongQ48059603
Characterisation of the CTX-M-15-encoding gene in Klebsiella pneumoniae strains from the Barcelona metropolitan area: plasmid diversity and chromosomal integrationQ48065261
Dissemination of the CTX-M-25 family beta-lactamases among Klebsiella pneumoniae, Escherichia coli and Enterobacter cloacae and identification of the novel enzyme CTX-M-41 in Proteus mirabilis in Israel.Q48074740
Identification of novel plasmid-mediated extended-spectrum beta-lactamase CTX-M-57 in Salmonella enterica serovar TyphimuriumQ48076167
The emergence of a novel ceftazidime-resistant CTX-M extended-spectrum beta-lactamase, CTX-M-55, in both community-onset and hospital-acquired infections in ThailandQ48080044
Interspecies spread of CTX-M-32 extended-spectrum beta-lactamase and the role of the insertion sequence IS1 in down-regulating bla CTX-M gene expression.Q48081190
Emergence of CTX-M-12 extended-spectrum beta-lactamase-producing Escherichia coli in Korea.Q48084472
A novel ceftazidime-hydrolysing extended-spectrum beta-lactamase, CTX-M-54, with a single amino acid substitution at position 167 in the omega loop.Q48086649
The partial 3'-conserved segment duplications in the integrons In6 from pSa and In7 from pDGO100 have a common originQ48112123
Surveillance of extended-spectrum beta-lactamases from clinical samples and faecal carriers in Barcelona, SpainQ48116088
Characterization of the highly variable region surrounding the bla(CTX-M-9) gene in non-related Escherichia coli from BarcelonaQ48119358
Nucleotide sequence of the kanamycin resistance transposon Tn903Q48410053
Hospital outbreak of MEN-1-derived extended spectrum beta-lactamase-producing Klebsiella pneumoniaeQ49262115
Epidemiological investigation of Salmonella enterica serovar Kedougou in ThailandQ50045427
CTX-M-37 in Salmonella enterica serotype Isangi from Durban, South AfricaQ50077387
Characterization of the first CTX-M-14-producing Salmonella enterica serotype Enteritidis isolate.Q50099452
The occurrence of the first two CTX-M-3 and TEM-1 producing isolates of Salmonella enterica serovar Oranienburg in PolandQ50104050
Characterization of plasmids encoding blaESBL and surrounding genes in Spanish clinical isolates of Escherichia coli and Klebsiella pneumoniae.Q50629251
High prevalence of bla(CTX-M) extended-spectrum β-lactamase genes in Escherichia coli isolates from pets and emergence of CTX-M-64 in China.Q50677339
IncN plasmids carrying bla CTX-M-1 in Escherichia coli isolates on a dairy farm.Q51608555
A novel IS26 structure surrounds blaCTX-M genes in different plasmids from German clinical Escherichia coli isolates.Q51788193
DNA sequence analysis of the genetic environment of various blaCTX-M genes.Q52567224
Incidence of class A extended-spectrum beta-lactamases in Champagne-Ardenne (France): a 1 year prospective study.Q52581834
A new plasmidic cefotaximase in a clinical isolate of Escherichia coli.Q54316090
Prevalence and types of extended-spectrum beta-lactamases among urinary Escherichia coli and Klebsiella spp. in New Zealand.Q54398792
The identification of CTX-M-14, TEM-52, and CMY-1 enzymes in Escherichia coli isolated from the Han River in Korea.Q54414663
Replicon typing of plasmids in Escherichia coli producing extended-spectrum beta-lactamases.Q54415321
Prevalence of rectal carriage of extended-spectrum beta-lactamase-producing Escherichia coli among elderly people in community settings in China.Q54417152
A novel bla(CTX-M-14) gene-harboring complex class 1 integron with an In4-like backbone structure from a clinical isolate of Escherichia coli.Q54418292
The bla(CTX-M-1) gene located in a novel complex class I integron bearing an ISCR1 element in Escherichia coli isolates from Zhenjiang, China.Q54419232
CTX-M: changing the face of ESBLs in EuropeQ36678524
Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene poolQ36949494
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidimeQ37032894
Identification and classification of bacterial plasmidsQ37064518
Chromosomal integration of the extended-spectrum beta-lactamase gene blaCTX-M-15 in Salmonella enterica serotype Concord isolates from internationally adopted childrenQ37190698
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.Q37190813
Resistance plasmid families in EnterobacteriaceaeQ37204254
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 cloneQ37392921
Nosocomial transmission of CTX-M-2 beta-lactamase-producing Acinetobacter baumannii in a neurosurgery wardQ37511391
Dramatic increase in prevalence of fecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae during nonoutbreak situations in SpainQ37576488
Community-onset disease caused by Citrobacter freundii producing a novel CTX-M beta-lactamase, CTX-M-30, in CanadaQ37598697
Molecular and kinetic comparison of the novel extended-spectrum beta-lactamases CTX-M-25 and CTX-M-26.Q37624427
Beta-lactamases identified in clinical isolates of Pseudomonas aeruginosaQ37756180
The CTX-M conundrum: dissemination of plasmids and Escherichia coli clonesQ37833633
Epidemiology and genetics of VIM-type metallo-β-lactamases in Gram-negative bacilliQ37859396
IMP-type metallo-β-lactamases in Gram-negative bacilli: distribution, phylogeny, and association with integronsQ37894745
Acinetobacter: a potential reservoir and dispenser for β-lactamasesQ37946953
Widely distributed and predominant CTX-M extended-spectrum beta-lactamases in Amsterdam, The Netherlands.Q38473574
Prevalence of broad-spectrum cephalosporin-resistant Escherichia coli isolates in food samples in Tunisia, and characterization of integrons and antimicrobial resistance mechanisms implicatedQ38902672
Outbreak of Salmonella enterica serotype Infantis producing ArmA 16S RNA methylase and CTX-M-15 extended-spectrum β-lactamase in a neonatology ward in Constantine, AlgeriaQ39288529
Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain.Q39474489
Nucleotide sequence and characterization of a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-10) isolated in SpainQ39476379
Characterization of a chromosomally encoded extended-spectrum class A beta-lactamase from Kluyvera cryocrescensQ39479254
A 1998 survey of extended-spectrum beta-lactamases in Enterobacteriaceae in France. The French Study GroupQ39537314
CTX-M-2 and a new CTX-M-39 enzyme are the major extended-spectrum beta-lactamases in multiple Escherichia coli clones isolated in Tel Aviv, Israel.Q39609493
Ceftazidime-hydrolysing CTX-M-15 extended-spectrum beta-lactamase (ESBL) in PolandQ39614205
Genes encoding TEM-4, SHV-2, and CTX-M-10 extended-spectrum beta-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000).Q39651162
ColE1-like plasmid pIP843 of Klebsiella pneumoniae encoding extended-spectrum beta-lactamase CTX-M-17.Q39651638
Novel class 1 integron (InS21) carrying blaCTX-M-2 in Salmonella enterica serovar infantisQ39652184
blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513.Q39652238
Novel complex sul1-type integron in Escherichia coli carrying bla(CTX-M-9).Q39652578
Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of ChinaQ39652923
Chromosome-encoded Ambler class A beta-lactamase of Kluyvera georgiana, a probable progenitor of a subgroup of CTX-M extended-spectrum beta-lactamasesQ39671119
Epidemiology of extended-spectrum beta-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year periodQ39697608
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbeta-lactamaseQ311379
Gram-negative bacteriaQ632006
gram-negative bacterial infectionQ19597369
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)79-101
P577publication date2012-06-15
2013-02-01
P1433published inCritical Reviews in MicrobiologyQ5186671
P1476titleEpidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria
P478volume39

Reverse relations

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Q35241687Factors that affect transfer of the IncI1 β-lactam resistance plasmid pESBL-283 between E. coli strains
Q36063941First Description of the Extended Spectrum-Beta-Lactamase Gene blaCTX-M-109 in Salmonella Grumpensis Strains Isolated from Neonatal Nosocomial Infections in Dakar, Senegal
Q28354075First Report of Group CTX-M-9 Extended Spectrum Beta-Lactamases in Escherichia coli Isolates from Pediatric Patients in Mexico
Q37026709Genetic characterization of IncI2 plasmids carrying blaCTX-M-55 spreading in both pets and food animals in China
Q52640052Genetic contexts related to the diffusion of plasmid-mediated CTX-M-55 extended-spectrum beta-lactamase isolated from Enterobacteriaceae in China.
Q37413795High Prevalence of ESBL-Producing Klebsiella pneumoniae Causing Community-Onset Infections in China.
Q41789763High Prevalence of β-lactamase and Plasmid-Mediated Quinolone Resistance Genes in Extended-Spectrum Cephalosporin-Resistant Escherichia coli from Dogs in Shaanxi, China
Q40992004High frequency of virulence genes among Escherichia coli with the blaCTX-M genotype from diarrheic piglets in China
Q64086207High prevalence and characterization of extended-spectrum ß-lactamase producing Enterobacteriaceae in Chadian hospitals
Q97418471High-resolution characterisation of ESBL/pAmpC-producing Escherichia coli isolated from the broiler production pyramid
Q61779222Increasing prevalence of extended-spectrum cephalosporin-resistant Escherichia coli in food animals and the diversity of CTX-M genotypes during 2003–2012
Q30386767Limited transmission of bla(CTX-M-9)-type-positive Escherichia coli between humans and poultry in Vietnam.
Q41715581Loop-mediated isothermal amplification assay targeting the blaCTX-M9 gene for detection of extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae
Q26747594Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
Q56517171Molecular characterization of extended spectrum β -lactamases enterobacteriaceae causing lower urinary tract infection among pediatric population
Q85634678Molecular characterization of the extended-spectrum beta-lactamase (ESBL)-producing Shigella spp. in Shanghai
Q38272908Molecular mechanisms of antibiotic resistance.
Q39072691Novel approaches to the treatment of bacterial biofilm infections
Q57807510Prevalence and antibiotic susceptibility pattern of CTX-M type extended-spectrum β-lactamases among clinical isolates of gram-negative bacilli in Jimma, Ethiopia
Q41117625Prevalence and characteristics of extended-spectrum β-lactamase genes in Escherichia coli isolated from piglets with post-weaning diarrhea in Heilongjiang province, China
Q53703618Prevalence of ESBL/AmpC genes and specific clones among the third-generation cephalosporin-resistant Enterobacteriaceae from canine and feline clinical specimens in Japan.
Q57808208Prevalence of Integrons and Insertion Sequences in ESBL-Producing Isolated from Different Sources in Navarra, Spain
Q40562293Prevalence of O25b-ST131 clone among Escherichia coli strains producing CTX-M-15, CTX-M-14 and CTX-M-92 β-lactamases
Q90476168Prevalence of blaCTX-M Gene among Extended-Spectrum β-Lactamases Producing Klebsiella pneumoniae Clinical Isolates in Iran: A Meta-Analysis
Q35666937Rapid and sensitive detection of antibiotic resistance on a programmable digital microfluidic platform
Q35764110Recent Emergence of Escherichia coli with Cephalosporin Resistance Conferred by blaCTX-M on Washington State Dairy Farms
Q35914890Simple and rapid sample preparation system for the molecular detection of antibiotic resistant pathogens in human urine.
Q57174160Tackling the Antibiotic Resistance Caused by Class A -Lactamases through the Use of -Lactamase Inhibitory Protein
Q64946548The Emergence of Chromosomally Located bla CTX-M-55 in Salmonella From Foodborne Animals in China.
Q55222869The Growing Genetic and Functional Diversity of Extended Spectrum Beta-Lactamases.
Q28550451The Widespread Presence of a Multidrug-Resistant Escherichia coli ST131 Clade among Community-Associated and Hospitalized Patients
Q30300020The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae
Q90099755Wastewater as a Probable Environmental Reservoir of Extended-Spectrum-β-Lactamase Genes: Detection of Chimeric β-Lactamases CTX-M-64 and CTX-M-123

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