Colorectal cancer chemoprevention by mesalazine and its derivatives.

scientific article published on 04 June 2012

Colorectal cancer chemoprevention by mesalazine and its derivatives. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1155/2012/980458
P932PMC publication ID3373216
P698PubMed publication ID22701310
P5875ResearchGate publication ID225376515

P50authorCarmine StolfiQ50105747
P2093author name stringFrancesco Pallone
Giovanni Monteleone
P2860cites workUbiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
The risk of colorectal cancer in ulcerative colitis: a meta-analysisQ24669747
Genetic instabilities in human cancersQ28131826
NSAIDs and chemopreventionQ28167254
Mesalazine improves replication fidelity in cultured colorectal cellsQ28175662
Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapyQ28176737
COX-2 inhibition and colorectal cancerQ28208652
Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phaseQ28280868
Cell-cycle checkpoints and cancerQ28293996
5-aminosalicylate is not chemoprophylactic for colorectal cancer in IBD: a population based study.Q51048836
Mesalazine-induced apoptosis of colorectal cancer: on the verge of a new chemopreventive era?Q61481511
Cancer surveillance in ulcerative colitis. Experience over 15 yearsQ72556204
Mesalazine changes apoptosis and proliferation in normal mucosa of patients with sporadic polyps of the large bowelQ73551359
Inflammation and colorectal cancer: IBD-associated and sporadic cancer comparedQ77504037
Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitisQ79293504
Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancerQ79378758
Cyclin-dependent kinase pathways as targets for cancer treatmentQ28306405
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Linking colorectal cancer to Wnt signalingQ29619810
Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studiesQ33987498
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
Family history as a risk factor for colorectal cancer in inflammatory bowel diseaseQ34514772
Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in miceQ34530870
Impact of EGFR expression on colorectal cancer patient prognosis and survivalQ34553435
Ulcerative colitis and colorectal cancer. A population-based studyQ34634203
5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpointQ35728207
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort studyQ36328183
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gammaQ36403491
Review article: mode of action and delivery of 5-aminosalicylic acid - new evidenceQ36580628
Colorectal cancer surveillance in inflammatory bowel disease: the search continuesQ37122138
Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine.Q37627928
Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease?Q37635008
Review article: colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel diseaseQ37892612
5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.Q39424739
2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.Q39494880
Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levelsQ39981730
Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.Q40057258
Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activityQ40275132
Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cellsQ40388136
Backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitisQ40721412
Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and preventionQ42039909
Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.Q42324127
5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modesQ43272637
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.Q43279593
Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in ratsQ43566230
Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cellsQ44381247
Improvement of replication fidelity by certain mesalazine derivatives.Q44383299
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.Q44755672
The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease.Q45099623
5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitisQ45268161
Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomasQ46374818
PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cellsQ46547392
5-aminosalicylic acid given in the remission stage of colitis suppresses colitis-associated cancer in a mouse colitis modelQ46920668
A positive role for the PP2A catalytic subunit in Wnt signal transduction.Q47826110
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectWnt signaling pathwayQ155769
mesalazineQ412479
colorectal carcinomaQ25493920
colorectal neoplasmQ58833976
cell survivalQ70690408
P304page(s)980458
P577publication date2012-06-04
P1433published inJournal of Biomedicine and BiotechnologyQ15752146
P1476titleColorectal cancer chemoprevention by mesalazine and its derivatives
P478volume2012

Reverse relations

cites work (P2860)
Q28596448BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling
Q39025709Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis.
Q46215033DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid
Q64272815Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer
Q92934841In Vitro Evaluation of the Phytopharmacological Potential of Sargassum incisifolium for the Treatment of Inflammatory Bowel Diseases
Q90640128Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer
Q37262181The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ.
Q26865429The complexities of epidemiology and prevention of gastrointestinal cancers
Q48182692The risk of colorectal cancer is related to frequent hospitalization of IBD in an Asian population: results from a nationwide study

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