Wnt pathway regulation of embryonic stem cell self-renewal

scientific article published on September 2012

Wnt pathway regulation of embryonic stem cell self-renewal is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/CSHPERSPECT.A007971
P932PMC publication ID3428775
P698PubMed publication ID22952393
P5875ResearchGate publication ID230804945

P2093author name stringBradley J Merrill
P2860cites workThe Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressorsQ22003989
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4Q22008002
LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptorQ24315815
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130Q24318173
Core transcriptional regulatory circuitry in human embryonic stem cellsQ24322016
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin geneQ24529898
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cellsQ24534271
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Q24600230
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cellsQ24616059
GSK-3: tricks of the trade for a multi-tasking kinaseQ24624069
Metastable pluripotent states in NOD-mouse-derived ESCsQ24645721
Establishment in culture of pluripotential cells from mouse embryosQ27860625
Embryonic stem cell lines derived from human blastocystsQ27861010
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cellsQ28176663
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cellsQ28176681
An extended transcriptional network for pluripotency of embryonic stem cellsQ28273615
Lack of beta-catenin affects mouse development at gastrulationQ28274575
Oncostatin M binds the high-affinity leukemia inhibitory factor receptorQ28282168
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cellsQ28291434
Promotion of reprogramming to ground state pluripotency by signal inhibitionQ28473911
Dissecting self-renewal in stem cells with RNA interferenceQ28506922
T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathwaysQ28506950
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factorsQ28506983
Requirement for beta-catenin in anterior-posterior axis formation in miceQ28507627
POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryosQ28511464
Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryosQ28512654
Multipotent cell lineages in early mouse development depend on SOX2 functionQ28513175
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewalQ28586947
Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic developmentQ28587194
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cellsQ28587342
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsQ28590205
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cellsQ28593119
Integration of external signaling pathways with the core transcriptional network in embryonic stem cellsQ29547179
The ground state of embryonic stem cell self-renewalQ29547196
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitorQ29614622
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3Q29614624
Control of the embryonic stem cell stateQ29614793
Derivation of pluripotent epiblast stem cells from mammalian embryosQ29614819
New cell lines from mouse epiblast share defining features with human embryonic stem cellsQ29614820
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cellsQ29615089
Nanog safeguards pluripotency and mediates germline developmentQ29616482
Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cellsQ31081839
Non-cell-autonomous stimulation of stem cell proliferation following ablation of Tcf3.Q33712458
A PiggyBac-based recessive screening method to identify pluripotency regulatorsQ33886516
Brachyury is a target gene of the Wnt/beta-catenin signaling pathwayQ33892439
Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small moleculesQ33929545
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiationQ33935135
A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency.Q34107595
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cellsQ34149498
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptidesQ34167801
Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signallingQ34211306
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.Q34361342
Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene ExpressionQ34378505
Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cellsQ34405302
Clonal analysis of epiblast fate during germ layer formation in the mouse embryo.Q34740870
Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.Q34752073
Wnt signaling mediates self-organization and axis formation in embryoid bodiesQ34872357
Klf4 reverts developmentally programmed restriction of ground state pluripotencyQ34947539
Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury inductionQ35037448
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewalQ35085761
Diversity of LEF/TCF action in development and diseaseQ36672669
Chromosomal transposition of PiggyBac in mouse embryonic stem cellsQ36737096
Epigenetic reprogramming and induced pluripotencyQ37201452
Back and forth between cell fate specification and movement during vertebrate gastrulationQ37250000
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.Q37336002
The transcriptional and signalling networks of pluripotencyQ37871828
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.Q38256000
Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewalQ38290924
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formationQ38473082
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanismQ39597671
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cellsQ39794349
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell linesQ40125072
Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cellsQ40188614
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and miceQ40386192
Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cellsQ40400343
Beta-catenin signaling is required for neural differentiation of embryonic stem cellsQ40533744
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signalingQ40690911
Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activityQ41712875
Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification.Q42183168
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.Q43121593
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cellsQ43140844
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cellsQ45259297
Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activationQ46952924
WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells.Q50746171
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.Q50893380
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells.Q51249622
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages.Q51896215
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.Q51921401
A core Klf circuitry regulates self-renewal of embryonic stem cells.Q51964604
Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.Q52007979
Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse.Q52254748
Histogenetic and neoplastic potential of different regions of the mouse embryonic egg cylinder.Q52280985
An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse.Q52287779
P433issue9
P921main subjectstem cell self-renewalQ107637617
P304page(s)a007971
P577publication date2012-09-01
P1433published inCold Spring Harbor Perspectives in BiologyQ3927509
P1476titleWnt pathway regulation of embryonic stem cell self-renewal
P478volume4

Reverse relations

cites work (P2860)
Q46193130A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate
Q38912247A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells
Q27347251Activation of Wnt/ß-catenin signaling in ESC promotes rostral forebrain differentiation in vitro
Q35804223Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation
Q37398471Brain tumor specifies intermediate progenitor cell identity by attenuating β-catenin/Armadillo activity
Q38813240Ciprofloxacin Improves the Stemness of Human Dermal Papilla Cells.
Q91679517Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells
Q60919909Inhibition of MEK1/2 and GSK3 (2i system) affects blastocyst quality and early differentiation of porcine parthenotes
Q36149368Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells
Q64950989Intracellular Calcium Determines the Adipogenic Differentiation Potential of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells via the Wnt5a/β-Catenin Signaling Pathway.
Q37232939KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer
Q35216180MicroRNA modulation induced by AICA ribonucleotide in J1 mouse ES cells
Q91839621PTK-7 Expression in Gastric Cancer: A Prognostic Determinant
Q38150805Postsynaptic assembly: a role for Wnt signaling
Q54565602Prerequisite OCT4 Maintenance Potentiates the Neural Induction of Differentiating Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.
Q92712869Protein Kinases and Their Inhibitors in Pluripotent Stem Cell Fate Regulation
Q36284219Retracted: Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation
Q33785287SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination
Q33625794Signaling Molecules Governing Pluripotency and Early Lineage Commitments in Human Pluripotent Stem Cells
Q36200964Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm
Q89427974Temporary, Systemic Inhibition of the WNT/β-Catenin Pathway promotes Regenerative Cardiac Repair following Myocardial Infarct
Q37543996The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells
Q36515479The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
Q33796203The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states
Q37514374Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells
Q33917414Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
Q92410960Wnt/Beta-Catenin Signaling and Prostate Cancer Therapy Resistance
Q37369222Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells

Search more.