The ACE2 gene: its potential as a functional candidate for cardiovascular disease.

scientific article published on January 2013

The ACE2 gene: its potential as a functional candidate for cardiovascular disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/CS20120269
P698PubMed publication ID23013041

P50authorStephen HarrapQ30519277
Sheila K PatelQ57054982
Louise M BurrellQ88223744
P2093author name stringElena Velkoska
P2860cites workX-inactivation profile reveals extensive variability in X-linked gene expression in femalesQ22122481
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidaseQ22254730
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Acute kidney injury in the rat causes cardiac remodelling and increases angiotensin-converting enzyme 2 expressionQ28583180
Plasma ACE2 activity is an independent prognostic marker in Chagas' disease and equally potent as BNP.Q48315421
N-terminal pro-brain natriuretic peptide and angiotensin-converting enzyme-2 levels and their association with postoperative cardiac complications after emergency orthopedic surgery.Q48633775
Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications.Q51374898
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Association of angiotensin-converting enzyme 2 gene A/G polymorphism and elevated blood pressure in Chinese patients with metabolic syndrome.Q51820362
No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension.Q51995128
Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study.Q52855193
Association of ACE, ACE2 and UTS2 polymorphisms with essential hypertension in Han and Dongxiang populations from north-western China.Q54590701
Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 DiabetesQ57243271
Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in menQ57315164
Angiotensin-converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesionsQ58215379
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney diseaseQ33387233
Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patientsQ33555002
Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone systemQ33799399
Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt studyQ33932245
Genetic variants in the apelin system and blood pressure responses to dietary sodium interventions: a family-based association studyQ34001103
Angiotensin-(1-7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy.Q34480216
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ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.Q34784864
Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.Q34830604
Genes that escape from X inactivationQ35104916
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunitQ35152116
Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes.Q35229766
Angiotensin-converting enzyme 2: the first decadeQ35550937
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin systemQ35567432
Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.Q35597966
ACE2, a new regulator of the renin-angiotensin systemQ35756519
Genetic variation in angiotensin-converting enzyme 2 gene is associated with extent of left ventricular hypertrophy in hypertrophic cardiomyopathyQ36773270
Genetic variation in angiotensin-converting enzyme-related pathways associated with sudden cardiac arrest riskQ37375407
Progression of cardiovascular damage: the role of renin-angiotensin system blockadeQ37681732
Angiotensin-converting enzyme 2 is a key modulator of the renin-angiotensin system in cardiovascular and renal diseaseQ37811789
A polymorphic miR-155 binding site in AGTR1 is associated with cardiac hypertrophy in Friedreich ataxia.Q37902766
Renal function and blood pressure: molecular insights into the biology of endothelin-1.Q37926823
Association between renin-angiotensin-aldosterone system-related genes and blood pressure in a Korean populationQ38476861
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomainQ40037190
Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor.Q40130425
Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).Q40404194
Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.Q40510688
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).Q42447014
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy.Q44353743
Angiotensin converting enzyme 2 gene expression increased compensatory for left ventricular remodeling in patients with end-stage heart failureQ45094749
Myocardial infarction increases ACE2 expression in rat and humans.Q45238600
Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2.Q46120246
ACE2 gene polymorphism and essential hypertension: an updated meta-analysis involving 11,051 subjectsQ46273463
Identification of angiotensin converting enzyme 2 in the rodent retina.Q46374769
Immunolocalization of ACE2 and AT2 receptors in rabbit atherosclerotic plaques.Q46663979
Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controlsQ46678604
Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patientsQ46716852
Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.Q46966464
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcardiovascular diseaseQ389735
P304page(s)65-76
P577publication date2013-01-01
P1433published inClinical ScienceQ372419
P1476titleThe ACE2 gene: its potential as a functional candidate for cardiovascular disease
P478volume124

Reverse relations

cites work (P2860)
Q35760437ACE2 and Microbiota: Emerging Targets for Cardiopulmonary Disease Therapy
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