| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Peter B Stathopulos | |
| Mitsuhiko Ikura | |||
| Fernando J Amador | |||
| Masahiro Enomoto | |||
| Min-duk Seo | |||
| Noboru Ishiyama | |||
| P2860 | cites work | Central core disease | Q21202972 |
| Malignant hyperthermia | Q21203008 | ||
| Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features | Q24294249 | ||
| The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium | Q24319842 | ||
| Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans | Q24608179 | ||
| Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating | Q27331094 | ||
| Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand | Q27639992 | ||
| Crystal structure of type I ryanodine receptor amino-terminal -trefoil domain reveals a disease-associated mutation"hot spot"loop | Q27656078 | ||
| Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations | Q27658171 | ||
| The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule | Q27665591 | ||
| Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor | Q27673043 | ||
| Structural and functional conservation of key domains in InsP3 and ryanodine receptors | Q27676937 | ||
| Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis | Q27860925 | ||
| MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods | Q27860929 | ||
| Inositol 1,4,5-trisphosphate receptors are strongly expressed in the nervous system, pharynx, intestine, gonad and excretory cell of Caenorhabditis elegans and are encoded by a single gene (itr-1) | Q28141268 | ||
| Two-state conformational changes in inositol 1,4,5-trisphosphate receptor regulated by calcium | Q43974199 | ||
| Autosomal recessive inheritance of RYR1 mutations in a congenital myopathy with cores. | Q44075701 | ||
| The spectrum of pathology in central core disease | Q44239689 | ||
| Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy | Q44417251 | ||
| Molecular genetics of exercise-induced polymorphic ventricular tachycardia: identification of three novel cardiac ryanodine receptor mutations and two common calsequestrin 2 amino-acid polymorphisms | Q44626982 | ||
| Evidence for related myopathies in exertional heat stroke and malignant hyperthermia | Q45743038 | ||
| Defective cardiac ryanodine receptor regulation during atrial fibrillation | Q46455370 | ||
| Ligand-induced conformational changes via flexible linkers in the amino-terminal region of the inositol 1,4,5-trisphosphate receptor. | Q46967424 | ||
| Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain. | Q48408123 | ||
| Immunohistochemical localization of ryanodine receptors in mouse central nervous system | Q48428051 | ||
| Differential Localization of Alternative Spliced Transcripts Encoding Inositol 1,4,5-Trisphosphate Receptors in Mouse Cerebellum and Hippocampus: In Situ Hybridization Study | Q48637156 | ||
| Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release | Q48738552 | ||
| Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/calcium release channel | Q48887625 | ||
| [3H]Azidodantrolene: synthesis and use in identification of a putative skeletal muscle dantrolene binding site in sarcoplasmic reticulum. | Q51457098 | ||
| Identification of Dantrolene Binding Sites in Porcine Skeletal Muscle Sarcoplasmic Reticulum | Q51596813 | ||
| Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel. | Q54017960 | ||
| Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia. | Q54644396 | ||
| A mutation in the human ryanodine receptor gene associated with central core disease | Q55670932 | ||
| Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia | Q55670933 | ||
| The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching | Q58492146 | ||
| Calcium Induced Release of Calcium from the Sarcoplasmic Reticulum of Skinned Skeletal Muscle Fibres | Q59063633 | ||
| Sudden unexplained death in a patient with a family history of malignant hyperthermia | Q41364909 | ||
| Expression of a ryanodine receptor-Ca2+ channel that is regulated by TGF-beta | Q41614489 | ||
| The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. | Q42054647 | ||
| Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating | Q42067925 | ||
| Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum | Q42150018 | ||
| Expression of a cardiac Ca(2+)-release channel isoform in mammalian brain | Q42796024 | ||
| High prevalence of exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia mutation-positive family members diagnosed by cascade genetic screening | Q43182612 | ||
| RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice | Q43204679 | ||
| Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia | Q28201561 | ||
| Involvement of the cardiac ryanodine receptor/calcium release channel in catecholaminergic polymorphic ventricular tachycardia | Q28216442 | ||
| The RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long QT syndrome: a comprehensive open reading [...] | Q28265202 | ||
| Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum | Q28266436 | ||
| Unicellular Ca2+ signaling 'toolkit' at the origin of metazoa | Q28274960 | ||
| Diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia | Q28299768 | ||
| Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts | Q28300366 | ||
| Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor | Q28586214 | ||
| Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors | Q28592356 | ||
| Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening | Q28594466 | ||
| Cathecolaminergic Polymorphic Ventricular Tachycardia | Q29036364 | ||
| The versatility and universality of calcium signalling | Q29547402 | ||
| Calcium signalling: dynamics, homeostasis and remodelling | Q29547635 | ||
| Flexible architecture of IP3R1 by Cryo-EM | Q30503400 | ||
| Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues | Q30989369 | ||
| Inositol 1,4,5-trisphosphate receptor contains multiple cavities and L-shaped ligand-binding domains. | Q31037430 | ||
| A Missense Mutation in the CASQ2 Gene Is Associated with Autosomal-Recessive Catecholamine-Induced Polymorphic Ventricular Tachycardia | Q33148925 | ||
| Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardia | Q33157356 | ||
| Parallelization of the MAFFT multiple sequence alignment program | Q33567535 | ||
| Ancestral Ca2+ signaling machinery in early animal and fungal evolution | Q33683404 | ||
| Loss of Inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis | Q33698914 | ||
| Genetics and pathogenesis of malignant hyperthermia | Q33789806 | ||
| Expression of inositol trisphosphate receptors. | Q33834374 | ||
| Arrhythmogenic right ventricular cardiomyopathy: diagnosis, prognosis, and treatment | Q33893877 | ||
| Dantrolene--a review of its pharmacology, therapeutic use and new developments | Q33976686 | ||
| Inositol trisphosphate receptor Ca2+ release channels. | Q33983069 | ||
| Ryanodine receptors: structure, expression, molecular details, and function in calcium release. | Q34024377 | ||
| Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites | Q34056171 | ||
| Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution | Q34089878 | ||
| RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes | Q34139686 | ||
| Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia. | Q34160930 | ||
| Anaesthetic deaths in a family | Q34251990 | ||
| The pore structure of the closed RyR1 channel | Q34318156 | ||
| Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum | Q34318323 | ||
| Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells | Q34328974 | ||
| Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. | Q34386939 | ||
| Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia | Q34629553 | ||
| Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. | Q34677465 | ||
| Malignant hyperthermia: a pharmacogenetic disease of Ca++ regulating proteins | Q34729251 | ||
| Altered ryanodine receptor function in central core disease: leaky or uncoupled Ca(2+) release channels? | Q34772571 | ||
| Domain organization of the type 1 inositol 1,4,5-trisphosphate receptor as revealed by single-particle analysis | Q34919159 | ||
| Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia. | Q35156823 | ||
| Mechanistic basis of bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium | Q35217047 | ||
| Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. | Q35534135 | ||
| Altered function and regulation of cardiac ryanodine receptors in cardiac disease | Q35601819 | ||
| Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants | Q35749144 | ||
| Novel therapeutic approaches for heart failure by normalizing calcium cycling | Q35825873 | ||
| Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. | Q35902619 | ||
| Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle | Q36234710 | ||
| unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction | Q36237253 | ||
| Complications associated with the administration of dantrolene 1987 to 2006: a report from the North American Malignant Hyperthermia Registry of the Malignant Hyperthermia Association of the United States | Q36398823 | ||
| Functional effects of central core disease mutations in the cytoplasmic region of the skeletal muscle ryanodine receptor | Q36436381 | ||
| Mutations in RYR1 in malignant hyperthermia and central core disease | Q36569488 | ||
| Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death. | Q36791253 | ||
| Alpha and beta isoforms of ryanodine receptor from chicken skeletal muscle are the homologues of mammalian RyR1 and RyR3. | Q36803594 | ||
| Multi-minicore Disease | Q36881612 | ||
| Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor. | Q37393446 | ||
| Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor. | Q37462351 | ||
| Purified ryanodine receptor of skeletal muscle sarcoplasmic reticulum forms Ca2+-activated oligomeric Ca2+ channels in planar bilayers | Q37482706 | ||
| The relationship between exertional heat illness, exertional rhabdomyolysis, and malignant hyperthermia | Q37555863 | ||
| The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump | Q37784543 | ||
| The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus. | Q37858339 | ||
| Ca(2+) signalling by IP(3) receptors. | Q37989031 | ||
| Ryanodine receptor calcium release channels: an evolutionary perspective. | Q37997673 | ||
| Ryanodine receptor physiology and its role in disease | Q37997675 | ||
| Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells | Q39729997 | ||
| Dantrolene. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity | Q39741068 | ||
| Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor | Q39755978 | ||
| Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant. | Q40474852 | ||
| Synthetic partial agonists reveal key steps in IP3 receptor activation | Q40523623 | ||
| Three-dimensional Rearrangements within Inositol 1,4,5-Trisphosphate Receptor by Calcium | Q40620855 | ||
| Promoter structure and gene expression of the mouse inositol 1,4,5-trisphosphate receptor type 3 gene | Q40778328 | ||
| Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor | Q41105707 | ||
| Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin | Q41124891 | ||
| P433 | issue | 6 | |
| P304 | page(s) | 331-342 | |
| P577 | publication date | 2012-12-01 | |
| P1433 | published in | Physiology | Q1091804 |
| P1476 | title | Themes and variations in ER/SR calcium release channels: structure and function | |
| P478 | volume | 27 |
| Q38924178 | Ca2+ transport and signalling in enamel cells |
| Q39850077 | Cellular electrophysiological principles that modulate secretion from synovial fibroblasts. |
| Q38806480 | DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE. |
| Q40377621 | Dental enamel cells express functional SOCE channels. |
| Q98280885 | Epsin-mediated degradation of IP3R1 fuels atherosclerosis |
| Q57182332 | From Stores to Sinks: Structural Mechanisms of Cytosolic Calcium Regulation |
| Q37678474 | Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets |
| Q38168374 | Intracellular calcium channels: inositol-1,4,5-trisphosphate receptors |
| Q34421643 | Management of malignant hyperthermia: diagnosis and treatment |
| Q34461228 | Muscling in on the ryanodine receptor |
| Q36081131 | Store-operated Ca2+ Entry Modulates the Expression of Enamel Genes. |
| Q26822659 | Structural aspects of calcium-release activated calcium channel function |
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