Structural and functional diversity in the activity and regulation of DAPK-related protein kinases

scientific article published on 05 July 2013

Structural and functional diversity in the activity and regulation of DAPK-related protein kinases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/FEBS.12384
P698PubMed publication ID23745726
P5875ResearchGate publication ID237094096

P50authorMatthias WilmannsQ17418321
Bertrand SimonQ38640076
P2093author name stringKoen Temmerman
P2860cites workDRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosisQ22003997
Structural basis for activation of the titin kinase domain during myofibrillogenesisQ22004264
Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosisQ22011046
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin bindingQ24290882
Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assemblyQ24291439
The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking systemQ24291920
Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated musclesQ24292672
The death-associated protein kinases: structure, function, and beyondQ24292704
Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activationQ24293502
New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoformQ24297457
Molecular basis of the death-associated protein kinase-calcium/calmodulin regulator complexQ24297574
Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulumQ24302073
Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sitesQ24309323
Mechanoenzymatics of titin kinaseQ24309951
GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signallingQ24311806
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expressionQ24313051
Calmodulin-kinases: modulators of neuronal development and plasticityQ24315924
A calmodulin-binding sequence in the C-terminus of human cardiac titin kinaseQ24318437
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagyQ24323360
The protein kinase complement of the human genomeQ24324497
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPKQ24336428
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinaseQ24555713
Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscleQ24631228
Identification of cardiac-specific myosin light chain kinaseQ24647058
Different obscurin isoforms localize to distinct sites at sarcomeresQ24684132
Design principles underpinning the regulatory diversity of protein kinasesQ27027644
Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppressionQ27635039
Structure of the dimeric autoinhibited conformation of DAPK2, a pro-apoptotic protein kinaseQ27667232
Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinaseQ27671288
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensionsQ27860532
The conformational plasticity of protein kinasesQ27860946
A conditional gating mechanism assures the integrity of the molecular force-sensor titin kinase.Q38699422
Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions.Q39998488
MSK1 activity is controlled by multiple phosphorylation sites.Q40487132
Substrate and pseudosubstrate interactions with protein kinases: determinants of specificityQ40592829
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activityQ41848995
Mechanisms for regulation of calmodulin kinase IIalpha by Ca(2+)/calmodulin and autophosphorylation of threonine 286.Q44220128
Stretch activates myosin light chain kinase in arterial smooth muscleQ44531184
Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1.Q47831662
2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitorQ47984433
Chemical genetics approach to identify peptide ligands that selectively stimulate DAPK-1 kinase activity.Q52676774
The sarcomeric M-band during development and in diseaseQ58200981
Ca(2+)/CaM-dependent kinases: from activation to functionQ28206372
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPKQ28259117
Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-diskQ28291323
Cardiac Myosin Light Chain Kinase Is Necessary for Myosin Regulatory Light Chain Phosphorylation and Cardiac Performance in VivoQ28295583
Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylationQ28299343
The significance of regulatory light chain phosphorylation in cardiac physiologyQ28305925
Kalrn plays key roles within and outside of the nervous systemQ28513985
Obscurin modulates the assembly and organization of sarcomeres and the sarcoplasmic reticulumQ28581398
Protein kinases: evolution of dynamic regulatory proteinsQ30014836
Insights into protein kinase regulation and inhibition by large scale structural comparisonQ30381908
Zipper-interacting protein kinase induces Ca(2+)-free smooth muscle contraction via myosin light chain phosphorylationQ30672001
A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activityQ30839612
A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates.Q30998954
The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanismQ34093106
Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complexQ34326272
The structure of alpha-helical coiled coilsQ34412200
Solution structure of a calmodulin-target peptide complex by multidimensional NMRQ34413755
Calmodulin in action: diversity in target recognition and activation mechanisms.Q34602616
The giant protein titin: a regulatory node that integrates myocyte signaling pathwaysQ34696141
Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generationQ35097285
DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicityQ35227449
Calmodulin's flexibility allows for promiscuity in its interactions with target proteins and peptidesQ35762292
Evolution of the eukaryotic protein kinases as dynamic molecular switchesQ36153870
Protein-protein interactions in the allosteric regulation of protein kinasesQ36641714
The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9Q36854910
A helix scaffold for the assembly of active protein kinasesQ36871421
Ca(2+)/calmodulin-dependent protein kinasesQ37157283
The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.Q37327303
A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunityQ37473160
Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell deathQ37624869
Cytoskeletal protein kinases: titin and its relations in mechanosensingQ37854510
Biochemistry of smooth muscle myosin light chain kinaseQ37874730
Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteinsQ38044430
Sites of interaction between kinase-related protein and smooth muscle myosin.Q38342805
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)5533-5550
P577publication date2013-07-05
P1433published inFEBS JournalQ1388041
P1476titleStructural and functional diversity in the activity and regulation of DAPK-related protein kinases
P478volume280

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cites work (P2860)
Q35754440Abnormal Localization of STK17A in Bile Canaliculi in Liver Allografts: An Early Sign of Chronic Rejection
Q37000278Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Q40657506Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1.
Q26996681Insights into the functions of the death associated protein kinases from C. elegans and other invertebrates
Q30388842Non-degradative Ubiquitination of Protein Kinases.
Q57027542Novel Functions of Death-Associated Protein Kinases through Mitogen-Activated Protein Kinase-Related Signals
Q59796192Prediction of GluN2B-CT/DAPK1 Interaction by Protein⁻Peptide Docking and Molecular Dynamics Simulation
Q90454347Pressure Overload in Mice With Haploinsufficiency of Striated Preferentially Expressed Gene Leads to Decompensated Heart Failure
Q35060723Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma
Q38174598Structure of giant muscle proteins
Q90392538Targeting Pim Kinases and DAPK3 to Control Hypertension

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