scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Craig Stevens | |
Ted R Hupp | |||
Yao Lin | |||
P2860 | cites work | The death-associated protein kinases: structure, function, and beyond | Q24292704 |
Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18 | Q24301023 | ||
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death | Q24310279 | ||
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression | Q24313051 | ||
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy | Q24323360 | ||
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK | Q24336428 | ||
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling | Q24536092 | ||
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase | Q24555713 | ||
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase | Q24564747 | ||
A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK | Q24645599 | ||
Antisense Depletion of Death-associated Protein Kinase Promotes Apoptosis | Q24646487 | ||
Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes | Q24646541 | ||
Inflammation and cancer | Q24649640 | ||
Autophagy suppresses tumorigenesis through elimination of p62 | Q24650670 | ||
DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals | Q24672929 | ||
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death | Q24673427 | ||
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy | Q28131727 | ||
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures | Q28200873 | ||
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis. | Q52576454 | ||
Chemical genetics approach to identify peptide ligands that selectively stimulate DAPK-1 kinase activity. | Q52676774 | ||
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis | Q56937812 | ||
Hsp90 Recognizes a Common Surface on Client Kinases | Q58008219 | ||
The mTOR pathway and its role in human genetic diseases | Q28285976 | ||
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes | Q28572782 | ||
Induction of autophagy in axonal dystrophy and degeneration | Q28589924 | ||
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb | Q28646935 | ||
Autophagy: from phenomenology to molecular understanding in less than a decade | Q29614174 | ||
Role and regulation of starvation-induced autophagy in the Drosophila fat body | Q29617035 | ||
Potential therapeutic applications of autophagy | Q29622862 | ||
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. | Q30480366 | ||
A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates. | Q30998954 | ||
A calmodulin-regulated protein kinase linked to neuron survival is a substrate for the calmodulin-regulated death-associated protein kinase | Q33204059 | ||
DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. | Q33314701 | ||
Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling | Q33381467 | ||
Control of death-associated protein kinase (DAPK) activity by phosphorylation and proteasomal degradation | Q33655851 | ||
The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism | Q34093106 | ||
Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis | Q35500554 | ||
Autophagy suppresses tumor progression by limiting chromosomal instability | Q35812219 | ||
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis | Q35855667 | ||
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation | Q35946374 | ||
From acute ER stress to physiological roles of the Unfolded Protein Response | Q36362397 | ||
DAPk protein family and cancer | Q36670688 | ||
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation | Q36745240 | ||
Signalling to translation: how signal transduction pathways control the protein synthetic machinery | Q36765810 | ||
TNF-mediated inflammatory disease. | Q37045764 | ||
Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase | Q37068977 | ||
Bcl-2 family members: dual regulators of apoptosis and autophagy | Q37170680 | ||
Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis | Q38304316 | ||
dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53. | Q38332879 | ||
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. | Q39937447 | ||
Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions. | Q39998488 | ||
A high throughput proteomics screen identifies novel substrates of death-associated protein kinase | Q40011747 | ||
DAP kinase mediates the phosphorylation of tropomyosin-1 downstream of the ERK pathway, which regulates the formation of stress fibers in response to oxidative stress | Q40076300 | ||
The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR. | Q40084671 | ||
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling | Q40364004 | ||
Organization of microtubules in axonal growth cones: a role for microtubule-associated protein MAP 1B. | Q40795926 | ||
To be or not to be, the level of autophagy is the question: dual roles of autophagy in the survival response to starvation | Q40955040 | ||
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK | Q41634356 | ||
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity | Q41848995 | ||
Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase | Q42834338 | ||
The TSC-mTOR signaling pathway regulates the innate inflammatory response | Q46321173 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell death | Q2383867 |
P304 | page(s) | 48-57 | |
P577 | publication date | 2009-10-26 | |
P1433 | published in | FEBS Journal | Q1388041 |
P1476 | title | Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death | |
P478 | volume | 277 |
Q55379064 | 5-Azacytidine treatment induces demethylation of DAPK1 and MGMT genes and inhibits growth in canine mammary gland tumor cells. |
Q39355488 | Azacytidine inhibits the proliferation of human promyelocytic leukemia cells (HL60) by demethylation of MGMT, DAPK and p16 genes |
Q38044430 | Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteins |
Q37384082 | Clinical effect of DAPK promoter methylation in gastric cancer: A systematic meta-analysis |
Q92340490 | Current Landscape of Epigenetics in Lung Cancer: Focus on the Mechanism and Application |
Q36916437 | DANGER is involved in high glucose-induced radioresistance through inhibiting DAPK-mediated anoikis in non-small cell lung cancer |
Q38156051 | DAPK and cytoskeleton-associated functions |
Q39271550 | DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions |
Q93081426 | Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease |
Q39376291 | Death-associated proliferation kinetic in normal and transformed cells |
Q53257548 | Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells. |
Q28083490 | Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review) |
Q35781937 | Deletion of MAP2K2/MEK2: a novel mechanism for a RASopathy? |
Q53861994 | Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition. |
Q90364104 | Drak/STK17A Drives Neoplastic Glial Proliferation through Modulation of MRLC Signaling |
Q38450146 | Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse. |
Q54978013 | Evaluation of the prognostic and physiological functions of death associated protein kinase 1 in breast cancer. |
Q33761873 | Gene methylation as a powerful biomarker for detection and screening of non-small cell lung cancer in blood |
Q39067355 | Hepatitis B virus x protein induces autophagy via activating death-associated protein kinase. |
Q54445753 | Histamine H2 receptor activation exacerbates myocardial ischemia/reperfusion injury by disturbing mitochondrial and endothelial function. |
Q35104325 | Identification, sequence analysis, and characterization of serine/threonine protein kinase 17A from Clonorchis sinensis |
Q91793781 | Inhibition of miR-34a-5p can rescue disruption of the p53-DAPK axis to suppress progression of clear cell renal cell carcinoma |
Q26996681 | Insights into the functions of the death associated protein kinases from C. elegans and other invertebrates |
Q42826052 | Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation |
Q38162917 | Kinase inhibitors for CNS diseases: an analysis of the recent patent literature |
Q38976702 | Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges |
Q38934431 | Methyl-donor depletion of head and neck cancer cells in vitro establishes a less aggressive tumour cell phenotype |
Q40434898 | Noncanonical Fungal Autophagy Inhibits Inflammation in Response to IFN-γ via DAPK1. |
Q38838459 | Overexpression of microRNA-133a inhibits ischemia-reperfusion-induced cardiomyocyte apoptosis by targeting DAPK2. |
Q42096961 | Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system |
Q38159469 | Post-translational regulation of the cellular levels of DAPK. |
Q35128520 | Promoter methylation of DAPK gene may contribute to the pathogenesis of nonsmall cell lung cancer: a meta-analysis |
Q37705217 | Quantitative and correlation analysis of the DNA methylation and expression of DAPK in breast cancer. |
Q38159467 | Regulation of inflammation by DAPK. |
Q35060723 | Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma |
Q24299676 | Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells |
Q34990739 | Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype |
Q38112751 | Structural and functional diversity in the activity and regulation of DAPK-related protein kinases |
Q36829473 | Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung |
Q93000405 | The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis |
Q38037753 | The therapeutic target Hsp90 and cancer hallmarks |
Q39095775 | The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. |
Q24313169 | Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway |