Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death

scientific article published on 26 October 2009

Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1742-4658.2009.07411.X
P698PubMed publication ID19878313
P5875ResearchGate publication ID38056634

P2093author name stringCraig Stevens
Ted R Hupp
Yao Lin
P2860cites workThe death-associated protein kinases: structure, function, and beyondQ24292704
Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18Q24301023
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damageQ24306743
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell deathQ24310279
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expressionQ24313051
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagyQ24323360
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPKQ24336428
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signalingQ24536092
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinaseQ24555713
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinaseQ24564747
A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPKQ24645599
Antisense Depletion of Death-associated Protein Kinase Promotes ApoptosisQ24646487
Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexesQ24646541
Inflammation and cancerQ24649640
Autophagy suppresses tumorigenesis through elimination of p62Q24650670
DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signalsQ24672929
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell deathQ24673427
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagyQ28131727
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signallingQ28131740
Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizuresQ28200873
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesisQ28246808
A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis.Q52576454
Chemical genetics approach to identify peptide ligands that selectively stimulate DAPK-1 kinase activity.Q52676774
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosisQ56937812
Hsp90 Recognizes a Common Surface on Client KinasesQ58008219
The mTOR pathway and its role in human genetic diseasesQ28285976
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomesQ28572782
Induction of autophagy in axonal dystrophy and degenerationQ28589924
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward RhebQ28646935
Autophagy: from phenomenology to molecular understanding in less than a decadeQ29614174
Role and regulation of starvation-induced autophagy in the Drosophila fat bodyQ29617035
Potential therapeutic applications of autophagyQ29622862
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.Q30480366
A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates.Q30998954
A calmodulin-regulated protein kinase linked to neuron survival is a substrate for the calmodulin-regulated death-associated protein kinaseQ33204059
DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.Q33314701
Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signalingQ33381467
Control of death-associated protein kinase (DAPK) activity by phosphorylation and proteasomal degradationQ33655851
The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanismQ34093106
Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesisQ35500554
Autophagy suppresses tumor progression by limiting chromosomal instabilityQ35812219
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesisQ35855667
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvationQ35946374
From acute ER stress to physiological roles of the Unfolded Protein ResponseQ36362397
DAPk protein family and cancerQ36670688
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translationQ36745240
Signalling to translation: how signal transduction pathways control the protein synthetic machineryQ36765810
TNF-mediated inflammatory disease.Q37045764
Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinaseQ37068977
Bcl-2 family members: dual regulators of apoptosis and autophagyQ37170680
Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosisQ38304316
dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53.Q38332879
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.Q39937447
Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions.Q39998488
A high throughput proteomics screen identifies novel substrates of death-associated protein kinaseQ40011747
DAP kinase mediates the phosphorylation of tropomyosin-1 downstream of the ERK pathway, which regulates the formation of stress fibers in response to oxidative stressQ40076300
The tumor suppressor DAPK is reciprocally regulated by tyrosine kinase Src and phosphatase LAR.Q40084671
The tumor suppressor DAP kinase is a target of RSK-mediated survival signalingQ40364004
Organization of microtubules in axonal growth cones: a role for microtubule-associated protein MAP 1B.Q40795926
To be or not to be, the level of autophagy is the question: dual roles of autophagy in the survival response to starvationQ40955040
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSKQ41634356
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activityQ41848995
Uncoordinated regulation of stress fibers and focal adhesions by DAP kinaseQ42834338
The TSC-mTOR signaling pathway regulates the innate inflammatory responseQ46321173
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)48-57
P577publication date2009-10-26
P1433published inFEBS JournalQ1388041
P1476titleDeath-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death
P478volume277

Reverse relations

cites work (P2860)
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