Multiple endocrine neoplasia syndromes associated with mutation of p27.

scientific article published on 26 June 2013

Multiple endocrine neoplasia syndromes associated with mutation of p27. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1078748405
P356DOI10.3275/9021
P698PubMed publication ID23800691

P50authorNatalia S. PellegataQ55691848
P2093author name stringM Lee
P2860cites workMultiple endocrine neoplasia type 2Q21203027
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humansQ24679314
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27Q28137860
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear exportQ28206256
Inhibitors of mammalian G1 cyclin-dependent kinasesQ29547907
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27Q29617346
Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosisQ33287624
Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).Q33606105
Regulation of the cdk inhibitor p27 and its deregulation in cancerQ33853211
Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.Q33898315
Guidelines for diagnosis and therapy of MEN type 1 and type 2.Q34104591
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localizationQ34150579
A polymorphism in the CDKN1B gene is associated with increased risk of hereditary prostate cancerQ34306506
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phaseQ34365993
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.Q34415250
A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterizationQ34635679
A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.Q34649802
Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomasQ34758456
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapyQ34763495
Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotypeQ35893635
Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation.Q35895504
Molecular genetics of multiple endocrine neoplasia types 1 and 2.Q36111935
Molecular pathogenesis of MEN2-associated tumorsQ36121928
Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanismsQ36327496
Impact of RET proto-oncogene analysis on the clinical management of multiple endocrine neoplasia type 2.Q36419268
p27(Kip1) V109G polymorphism and cancer risk: a systematic review and meta-analysisQ36451110
The multiple endocrine neoplasia syndromesQ36622153
The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutationsQ36735215
Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related statesQ37198026
Cyclin-dependent kinase inhibitor 1B (CDKN1B) gene variants in AIP mutation-negative familial isolated pituitary adenoma kindredsQ39403888
Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.Q41120998
Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphomaQ41302507
Cyclin E-CDK2 is a regulator of p27Kip1.Q42800258
Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinomaQ44951962
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasiaQ48079288
Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.Q53348388
Functional characterization of a rare germline mutation in the gene encoding the cyclin-dependent kinase inhibitor p27Kip1 (CDKN1B) in a Spanish patient with multiple endocrine neoplasia-like phenotype.Q54546392
Recessive transmission of a multiple endocrine neoplasia syndrome in the ratQ63951641
p27/Kip1 mutation found in breast cancerQ71067651
The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignanciesQ71934956
Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomasQ73833543
A novel p27 gene mutation in a case of unclassified myeloproliferative disorderQ81164172
Novel mutations in MEN1, CDKN1B and AIP genes in patients with multiple endocrine neoplasia type 1 syndrome in SpainQ82192110
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectmultiple endocrine neoplasiaQ1553018
P304page(s)781-787
P577publication date2013-06-26
P1433published inJournal of Endocrinological InvestigationQ15766847
P1476titleMultiple endocrine neoplasia syndromes associated with mutation of p27
P478volume36

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cites work (P2860)
Q37634917Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology.
Q54293020Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.
Q47159773Functional characterization of a CDKN1B mutation in a Sardinian kindred with multiple endocrine neoplasia type 4 (MEN4).
Q53683262Genetics of Cushing's Syndrome.
Q53131281Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.
Q33904619Loss-of-function mutations in the CABLES1 gene are a novel cause of Cushing's disease
Q38313735MicroRNA deregulation in parathyroid tumours suggests an embryonic signature.
Q39412594Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood
Q91758387Multiple endocrine neoplasia-like syndrome in 24 baboons (Papio spp.).
Q42695925Mutational and large deletion study of genes implicated in hereditary forms of primary hyperparathyroidism and correlation with clinical features.
Q38858270Towards a new classification of gastroenteropancreatic neuroendocrine neoplasms

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