| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | M J Servant | |
| P Coulombe | |||
| S Meloche | |||
| B Turgeon | |||
| P2860 | cites work | Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors | Q71934600 |
| Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta | Q71995235 | ||
| Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of p44mapk and p42mapk isoforms in the G1 phase and their inactivation at the G1/S transition | Q72299070 | ||
| Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery | Q72733057 | ||
| Mitogens for adult rat aortic vascular smooth muscle cells in serum-free primary culture | Q72790344 | ||
| Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells | Q72962088 | ||
| Angiotensin II activates phosphatidylinositol 3-kinase in vascular smooth muscle cells | Q73554726 | ||
| Cyclic AMP-mediated inhibition of angiotensin II-induced protein synthesis is associated with suppression of tyrosine phosphorylation signaling in vascular smooth muscle cells | Q73813633 | ||
| Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27 | Q73959940 | ||
| Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton | Q74047985 | ||
| Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function | Q24311568 | ||
| Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals | Q24314293 | ||
| p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest | Q24319021 | ||
| The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
| A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 | Q24322196 | ||
| Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex | Q24336704 | ||
| Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4 | Q24652482 | ||
| Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6 | Q24652510 | ||
| Human cyclin E, a nuclear protein essential for the G1-to-S phase transition | Q24652527 | ||
| Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
| The retinoblastoma protein and cell cycle control | Q27860722 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
| p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest | Q28258615 | ||
| Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase | Q28294919 | ||
| Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution | Q28300442 | ||
| p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene | Q28300451 | ||
| Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor | Q28301248 | ||
| p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
| Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15 | Q28610294 | ||
| Principles of CDK regulation | Q29547820 | ||
| The pathogenesis of atherosclerosis: a perspective for the 1990s | Q29547827 | ||
| Inhibitors of mammalian G1 cyclin-dependent kinases | Q29547907 | ||
| D-type cyclin-dependent kinase activity in mammalian cells | Q29614966 | ||
| G1 phase progression: cycling on cue | Q29615162 | ||
| The transforming growth factor-beta family | Q29615948 | ||
| Distinct roles for cyclin-dependent kinases in cell cycle control | Q29616480 | ||
| Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 | Q29617346 | ||
| G1 events and regulation of cell proliferation | Q29618317 | ||
| Platelet-derived growth factor-induced destabilization of smooth muscle alpha-actin mRNA. | Q30455733 | ||
| Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells | Q30460026 | ||
| Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells | Q30461802 | ||
| Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells | Q30462210 | ||
| Regulation of differentiation of vascular smooth muscle cells | Q30464387 | ||
| Optimization of the resolution of phosphoamino acids by one-dimensional thin-layer electrophoresis. | Q30466768 | ||
| Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHox | Q30471070 | ||
| Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27 | Q33887383 | ||
| Mechanisms of cyclin-dependent kinase inactivation by progestins | Q33993962 | ||
| Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides | Q34138108 | ||
| A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples | Q34721532 | ||
| Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II. | Q35605118 | ||
| Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells | Q36561469 | ||
| A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells | Q36654228 | ||
| Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. | Q36791514 | ||
| Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery | Q37367211 | ||
| Replication of smooth muscle cells in vascular disease | Q39731571 | ||
| Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. | Q40022664 | ||
| Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts | Q40023331 | ||
| Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). | Q40453377 | ||
| Platelet-derived growth factor receptor signals | Q40554673 | ||
| Mammalian G1 cyclins | Q40606646 | ||
| Angiotensin II receptors and angiotensin II receptor antagonists. | Q40846126 | ||
| Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter | Q41066935 | ||
| Cyclin D1 expression is a major target of the cAMP-induced inhibition of cell cycle entry in fibroblasts | Q41115200 | ||
| Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. | Q41120998 | ||
| Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells | Q41172015 | ||
| Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. | Q41173912 | ||
| Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts | Q41176644 | ||
| Translational control of p27Kip1 accumulation during the cell cycle | Q41213467 | ||
| Cyclin dependent kinase activating kinases | Q41239058 | ||
| Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin | Q41412030 | ||
| Immediate-early gene expression in response to hypertrophic and proliferative stimuli in pulmonary arterial smooth muscle cells. | Q41481604 | ||
| Agonist-selective regulation of polyphosphoinositide metabolism in pulmonary artery smooth muscle cells | Q41481706 | ||
| Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. | Q41508377 | ||
| Simultaneous induction of stimulatory and inhibitory signals by PDGF. | Q41553992 | ||
| A comparison of apparent mRNA half-life using kinetic labeling techniques vs decay following administration of transcriptional inhibitors | Q41663082 | ||
| Mitogenic effect of angiotensin II on rat carotid arteries and type II or III mesenteric microvessels but not type I mesenteric microvessels is mediated by endogenous basic fibroblast growth factor | Q41714293 | ||
| Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes | Q41975129 | ||
| Temporally and spatially coordinated expression of cell cycle regulatory factors after angioplasty | Q42435147 | ||
| Cyclin E-CDK2 is a regulator of p27Kip1. | Q42800258 | ||
| Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle | Q42813101 | ||
| Differential modulation of G1 cyclins and the Cdk inhibitor p27kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts | Q42813141 | ||
| Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall | Q44193259 | ||
| Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells | Q44595925 | ||
| Culture of renal arteriolar smooth muscle cells. Mitogenic responses to angiotensin II | Q44896978 | ||
| Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway | Q48046157 | ||
| Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1. | Q48057753 | ||
| Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
| Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. | Q50335523 | ||
| Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. | Q52543351 | ||
| Angiotensin II Activates pp60 c- src in Vascular Smooth Muscle Cells | Q57630610 | ||
| Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System | Q58198972 | ||
| Alpha 1-adrenoreceptor blockade reduces the angiotensin II-induced vascular smooth muscle cell DNA synthesis in the rat thoracic aorta and carotid artery | Q67488041 | ||
| Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells | Q67494064 | ||
| Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells | Q67544466 | ||
| Receptor-mediated effects of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats | Q67594183 | ||
| 3 Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to immobilon | Q67703557 | ||
| Angiotensin II-1 receptors mediate both vasoconstrictor and hypertrophic responses in rat aortic smooth muscle cells | Q67909923 | ||
| Platelet-derived growth factor and angiotensin II cause increases in cytosolic free calcium by different mechanisms in vascular smooth muscle cells | Q69588959 | ||
| Role of transforming growth factor-beta 1 in the cellular growth response to angiotensin II | Q70744714 | ||
| Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells | Q71143876 | ||
| A long-term receptor stimulation is requisite for angiotensin II-dependent DNA synthesis in vascular smooth muscle cells from spontaneously hypertensive rats | Q71289459 | ||
| Smooth muscle DNA replication in response to angiotensin II is regulated differently in the neointima and media at different times after balloon injury in the rat carotid artery. Role of AT1 receptor expression | Q71500906 | ||
| Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells | Q71522762 | ||
| Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II | Q71646095 | ||
| Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells | Q71680834 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 14 | |
| P304 | page(s) | 543-556 | |
| P577 | publication date | 2000-02-01 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms | |
| P478 | volume | 148 |
| Q24300746 | A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression |
| Q28571340 | ANG II stimulates phospholipase D through PKCzeta activation in VSMC: implications in adhesion, spreading, and hypertrophy |
| Q24319434 | Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway |
| Q33385005 | Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors |
| Q35694048 | Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation. |
| Q40852113 | BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway |
| Q43126373 | C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis |
| Q34981345 | CDKs and CKIs: molecular targets for tissue remodelling |
| Q28568449 | Calpain activation is required for glutamate-induced p27 down-regulation in cultured cortical neurons |
| Q40629309 | Cyclin dependent kinase inhibitor p27Kip1 is upregulated by hypoxia via an ARNT dependent pathway |
| Q54587476 | Cyclophilin A is required for M-CSF-dependent macrophage proliferation. |
| Q47445997 | Defective interaction between p27 and cyclin A-CDK complex in certain human cancer cell lines revealed by split YFP assay in living cells |
| Q30781182 | Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway |
| Q38717609 | Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity |
| Q33409763 | ER stress affects processing of MHC class I-associated peptides |
| Q41882057 | Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27kip1. |
| Q28579623 | Essential role of PKC-zeta in normal and angiotensin II-accelerated neointimal growth after vascular injury |
| Q44540468 | Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway |
| Q33930863 | Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling |
| Q64038810 | Expression of angiotensin type II receptor downregulates Cdk4 synthesis and inhibits cell-cycle progression |
| Q45052644 | Facilitation of proteasomal degradation of p27Kip1 by N-terminal cleavage and their sequence requirements |
| Q44619300 | Follicle Stimulating Hormone-Induced DNA Synthesis in the Granulosa Cells of Hamster Preantral Follicles Involves Activation of Cyclin-Dependent Kinase-4 Rather Than Cyclin D2 Synthesis1 |
| Q33877608 | Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation |
| Q42510566 | Id3 is a novel regulator of p27kip1 mRNA in early G1 phase and is required for cell-cycle progression |
| Q43148405 | Kruppel-like factor 5 shows proliferation-specific roles in vascular remodeling, direct stimulation of cell growth, and inhibition of apoptosis |
| Q35895475 | MENX and MEN4 |
| Q33717520 | Mitogenic regulation of p27(Kip1) gene is mediated by AP-1 transcription factors |
| Q38117023 | Multiple endocrine neoplasia syndromes associated with mutation of p27. |
| Q24563960 | N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome |
| Q42435242 | Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1. |
| Q28578929 | PYK2 signaling is required for PDGF-dependent vascular smooth muscle cell proliferation |
| Q34130676 | Paradigms of growth control: relation to Cdk activation |
| Q34300397 | Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions |
| Q37728747 | Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling |
| Q24683060 | Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation |
| Q34076834 | Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle |
| Q37678214 | Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1). |
| Q37349093 | Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells |
| Q39700439 | Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors |
| Q36953811 | S10 phosphorylation of p27 mediates atRA induced growth arrest in ovarian carcinoma cell lines |
| Q24297942 | Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells |
| Q38864826 | Stigmasterol protects against Ang II-induced proliferation of the A7r5 aortic smooth muscle cell-line |
| Q33754081 | Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor |
| Q37430782 | TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation |
| Q34416268 | Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases |
| Q47143838 | Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury. |
| Q40691690 | The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism |
| Q24792969 | The major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5'-UTR |
| Q41848509 | The non-classical MAP kinase ERK3 controls T cell activation |
| Q33952356 | The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells. |
| Q73771262 | The plant cyclin-dependent kinase inhibitor ICK1 has distinct functional domains for in vivo kinase inhibition, protein instability and nuclear localization |
| Q39675750 | Tumor necrosis factor receptor-associated factor-6 and ribosomal S6 kinase intracellular pathways link the angiotensin II AT1 receptor to the phosphorylation and activation of the IkappaB kinase complex in vascular smooth muscle cells |
| Q35745383 | XMRV accelerates cellular proliferation, transformational activity, and invasiveness of prostate cancer cells by downregulating p27(Kip1). |
| Q73933566 | beta-Migrating very low density lipoprotein (beta VLDL) activates smooth muscle cell mitogen-activated protein (MAP) kinase via G protein-coupled receptor-mediated transactivation of the epidermal growth factor (EGF) receptor: effect of MAP kinase a |
| Q42674798 | mRNA differential display identification of vascular smooth muscle early response genes regulated by PDGF. |
| Q36321251 | p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2. |
| Q28365491 | p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis |
| Q43802288 | p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation |
| Q37803487 | p27kip1: a new multiple endocrine neoplasia gene? |
| Q44524136 | sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation |
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