| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1010613501 |
| P356 | DOI | 10.1038/NRG3523 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/nrg3523 |
| P698 | PubMed publication ID | 23835440 |
| P5875 | ResearchGate publication ID | 247771389 |
| P50 | author | Teri Manolio | Q66829016 |
| P2860 | cites work | Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers | Q21563322 |
| A turning point in cancer research: sequencing the human genome | Q22065518 | ||
| Potential etiologic and functional implications of genome-wide association loci for human diseases and traits | Q22066284 | ||
| Fine-scale structural variation of the human genome | Q22122044 | ||
| An integrated encyclopedia of DNA elements in the human genome | Q22122150 | ||
| Finding the missing heritability of complex diseases | Q22122198 | ||
| Complement factor H polymorphism in age-related macular degeneration | Q24553334 | ||
| A map of human genome variation from population-scale sequencing | Q24617794 | ||
| Biological, clinical and population relevance of 95 loci for blood lipids | Q24622541 | ||
| Hundreds of variants clustered in genomic loci and biological pathways affect human height | Q24630979 | ||
| Beyond odds ratios — communicating disease risk based on genetic profiles | Q58047301 | ||
| Trends in lipids and lipoproteins in US adults, 1988-2010 | Q64128323 | ||
| The limitations of risk factors as prognostic tools | Q79445507 | ||
| Understanding type 1 diabetes through genetics: advances and prospects | Q82065036 | ||
| Genetic risk prediction--are we there yet? | Q83658297 | ||
| Ten years on--the human genome and medicine | Q84307372 | ||
| Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene | Q24632288 | ||
| MYH9 is associated with nondiabetic end-stage renal disease in African Americans | Q24653027 | ||
| Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis | Q24656576 | ||
| Genome-wide association meta-analysis for total serum bilirubin levels | Q24658179 | ||
| Genetic risk prediction in complex disease | Q27027720 | ||
| Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain | Q28266158 | ||
| A genome-wide association study identifies IL23R as an inflammatory bowel disease gene | Q28270603 | ||
| Genetic heterogeneity in human disease | Q28280100 | ||
| Genomewide association studies and assessment of the risk of disease | Q28288414 | ||
| Assessing and managing risk when sharing aggregate genetic variant data | Q28730043 | ||
| A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci | Q28943424 | ||
| Mapping and analysis of chromatin state dynamics in nine human cell types | Q29547552 | ||
| Common genetic variation and human traits | Q29614445 | ||
| Personal genomes: The case of the missing heritability | Q29614582 | ||
| Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma | Q29614903 | ||
| Evolution and functional impact of rare coding variation from deep sequencing of human exomes | Q29617587 | ||
| SLCO1B1 variants and statin-induced myopathy--a genomewide study | Q29619028 | ||
| Imputation-based analysis of association studies: candidate regions and quantitative traits | Q30833155 | ||
| Prediction and interaction in complex disease genetics: experience in type 1 diabetes | Q33479555 | ||
| Quantifying the underestimation of relative risks from genome-wide association studies | Q33855679 | ||
| Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations | Q34084456 | ||
| Statin-associated myopathy | Q34187996 | ||
| A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes. | Q34205887 | ||
| The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. | Q34276618 | ||
| Pharmacogenomics and individualized medicine: translating science into practice | Q34297575 | ||
| Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake | Q34626398 | ||
| Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction | Q34913385 | ||
| Copy number variants in pharmacogenetic genes | Q34975631 | ||
| Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses | Q35034902 | ||
| The genetics of asthma and allergic disease: a 21st century perspective | Q35152056 | ||
| Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition | Q35634476 | ||
| A refined molecular taxonomy of breast cancer | Q35838290 | ||
| Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women | Q35846927 | ||
| Inclusion of gene-gene and gene-environment interactions unlikely to dramatically improve risk prediction for complex diseases | Q36017113 | ||
| Randomized trial of personal genomics for preventive cardiology: design and challenges | Q36089235 | ||
| The SLCO1B1*5 genetic variant is associated with statin-induced side effects | Q36158024 | ||
| A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. | Q36243420 | ||
| What will diabetes genomes tell us? | Q36374101 | ||
| Phenotypic heterogeneity of genomic disorders and rare copy-number variants | Q36387744 | ||
| Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein | Q36719197 | ||
| A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer | Q36740528 | ||
| Genomics for the world | Q37003231 | ||
| Prediction of individual genetic risk of complex disease | Q37235762 | ||
| Extending genome-wide association studies to copy-number variation | Q37292884 | ||
| Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry | Q37301357 | ||
| Implementing genomic medicine in the clinic: the future is here | Q37328458 | ||
| GWA studies: rewriting the story of IBD. | Q37393352 | ||
| Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals | Q37409157 | ||
| Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects | Q37474395 | ||
| Clinical applications of diabetes antibody testing | Q37624232 | ||
| The genetics of statin-induced myopathy | Q37664962 | ||
| Uncovering the roles of rare variants in common disease through whole-genome sequencing | Q37755970 | ||
| Statin myopathy: a review of recent progress | Q37786520 | ||
| Clinical implications of pharmacogenetic variation on the effects of statins. | Q37818151 | ||
| Type 2 diabetes and obesity: genomics and the clinic | Q37885799 | ||
| Current status of genome-wide association studies in cancer | Q37890286 | ||
| Do genome-wide association scans have potential for translation? | Q37948858 | ||
| Genetic and genomic approaches to asthma: new insights for the origins | Q37960296 | ||
| Making progress: preserving beta cells in type 1 diabetes | Q37972677 | ||
| Therapeutic targeting of the complement system in age-related macular degeneration: a review. | Q37981256 | ||
| Towards a novel molecular classification of IBD. | Q38026408 | ||
| Genetics and the individualized prediction of fracture | Q38031141 | ||
| Clinical immunologic interventions for the treatment of type 1 diabetes | Q38036230 | ||
| Pathway-based classification of lung cancer: a strategy to guide therapeutic selection | Q39547890 | ||
| ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. | Q39920642 | ||
| Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function | Q39965118 | ||
| Assessing the role of HLA-linked and unlinked determinants of disease | Q40593830 | ||
| Predictive genetic testing in maturity-onset diabetes of the young (MODY). | Q40695057 | ||
| Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites. | Q41239048 | ||
| Value of genetic profiling for the prediction of coronary heart disease | Q44730516 | ||
| Polymorphisms associated with cholesterol and risk of cardiovascular events | Q46691746 | ||
| Shattuck lecture--medical and societal consequences of the Human Genome Project. | Q48582472 | ||
| Genomics reaches the clinic: from basic discoveries to clinical impact. | Q50510941 | ||
| Unraveling the genetic predisposition of ribavirin-induced anaemia. | Q50558841 | ||
| Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population. | Q53352652 | ||
| Deflating the Genomic Bubble | Q57745295 | ||
| Maturity-onset diabetes of the young (MODY): how many cases are we missing? | Q57920457 | ||
| P433 | issue | 8 | |
| P921 | main subject | genome-wide association study | Q1098876 |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 549-558 | |
| P577 | publication date | 2013-07-09 | |
| P1433 | published in | Nature Reviews Genetics | Q1071824 |
| P1476 | title | Bringing genome-wide association findings into clinical use. | |
| P478 | volume | 14 |
| Q37608734 | 8p22-23-rs2254546 as a susceptibility locus for Kawasaki disease: a case-control study and a meta-analysis |
| Q39022431 | A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. |
| Q48561722 | A Decade of Genetic and Metabolomic Contributions to Type 2 Diabetes Risk Prediction. |
| Q37575470 | A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis |
| Q47159542 | A Review of Pathway-Based Analysis Tools That Visualize Genetic Variants |
| Q35957063 | A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density |
| Q36310685 | A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts |
| Q37697205 | A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population |
| Q42362845 | A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study |
| Q37589578 | A scoring strategy combining statistics and functional genomics supports a possible role for common polygenic variation in autism |
| Q42838066 | A whole-genome simulator capable of modeling high-order epistasis for complex disease |
| Q38308481 | APOL1 nephropathy: from gene to mechanisms of kidney injury |
| Q27008236 | Advances in the genomics of common eye diseases |
| Q93111064 | Analysis of clinical significance and prospective molecular mechanism of main elements of the JAK/STAT pathway in hepatocellular carcinoma |
| Q36753746 | Analytical Validation of a Personalized Medicine APOL1 Genotyping Assay for Nondiabetic Chronic Kidney Disease Risk Assessment |
| Q92254371 | Applying Mental Model Methods to Characterize Understanding of Gene-Environment Influences: The Case of Podoconiosis in Ethiopia |
| Q60934709 | Association between a Genetic Risk Score Based on Single Nucleotide Polymorphisms of Coronary Artery Disease-Related Genes and Left Main Coronary Artery Disease |
| Q90576035 | Association study between a polymorphic poly-T repeat sequence in the promoter of the somatostatin gene and metabolic syndrome |
| Q34294964 | Autoimmune and autoinflammatory mechanisms in uveitis |
| Q38651981 | Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank |
| Q91865303 | Benefits and limitations of genome-wide association studies |
| Q40114829 | Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks |
| Q33813557 | Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. |
| Q36078688 | CHALLENGES FOR IMPLEMENTING A PTSD PREVENTIVE GENOMIC SEQUENCING PROGRAM IN THE U.S. MILITARY. |
| Q37070091 | Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease |
| Q35781030 | Can Genetics Predict Response to Complex Behavioral Interventions? Evidence from a Genetic Analysis of the Fast Track Randomized Control Trial |
| Q88718519 | Characterization of noncoding regulatory DNA in the human genome |
| Q38205413 | Cis-regulatory variation: significance in biomedicine and evolution |
| Q28648173 | ClinGen--the Clinical Genome Resource |
| Q34355357 | Clinical applications of age-related macular degeneration genetics |
| Q38707185 | Commentary: Should Pharmacogenomic Evidence Be Considered in Clinical Decision Making? Focus on Select Cardiovascular Drugs |
| Q38948164 | Common genetic variants in NEFL influence gene expression and neuroblastoma risk |
| Q30838858 | Compression and fast retrieval of SNP data |
| Q35664102 | Contrasting genetic architectures in different mouse reference populations used for studying complex traits. |
| Q30276980 | Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease |
| Q38204372 | Current Insights into the Joint Genetic Basis of Type 2 Diabetes and Coronary Heart Disease. |
| Q39119100 | Deep brain stimulation for dystonia: a novel perspective on the value of genetic testing |
| Q30661270 | Design of a randomized controlled trial of disclosing genomic risk of coronary heart disease: the Myocardial Infarction Genes (MI-GENES) study |
| Q38720002 | Detecting genetic association through shortest paths in a bidirected graph |
| Q31143790 | Disaggregating asthma: Big investigation versus big data |
| Q37644444 | Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits |
| Q38371172 | E-Science technologies in a workflow for personalized medicine using cancer screening as a case study |
| Q36008382 | Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes |
| Q57165221 | Epidemiology, aetiology, and management of ischaemic stroke in young adults |
| Q28649688 | Evolutionary signatures amongst disease genes permit novel methods for gene prioritization and construction of informative gene-based networks |
| Q89430640 | Fast score test with global null estimation regardless of missing genotypes |
| Q38843497 | Functional interpretation of non-coding sequence variation: concepts and challenges |
| Q34307550 | Functional logistic regression approach to detecting gene by longitudinal environmental exposure interaction in a case-control study. |
| Q55333371 | Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine. |
| Q34455119 | Gene-gene and gene-environment interactions in apolipoprotein L1 gene-associated nephropathy |
| Q38590582 | Genes affecting β-cell function in type 1 diabetes |
| Q40893703 | Genetic Epidemiology and Public Health: The Evolution From Theory to Technology |
| Q28079249 | Genetic Risk Factors for Ischemic and Hemorrhagic Stroke |
| Q37193266 | Genetic dissection of diabetes: facing the giant |
| Q34008801 | Genetic predisposition to colorectal cancer: where we stand and future perspectives |
| Q40641108 | Genetic-risk assessment of GWAS-derived susceptibility loci for type 2 diabetes in a 10 year follow-up of a population-based cohort study |
| Q87640680 | Genome editing for all |
| Q39158128 | Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back-Looking Forward to Next-Generation Innovation |
| Q92148453 | Genome-Wide Association Studies in Idiopathic Pulmonary Fibrosis: Bridging the Gap between Sequence and Consequence |
| Q40050014 | Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations |
| Q36067406 | Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice |
| Q99638192 | Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation |
| Q34473904 | Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models |
| Q90841517 | Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation |
| Q49843750 | Genomic screening for monogenic forms of diabetes. |
| Q41076261 | Genomics innovation: transforming healthcare, business, and the global economy |
| Q36117265 | Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism. |
| Q55249119 | High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing. |
| Q37090647 | Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies |
| Q46020569 | Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics. |
| Q64113992 | Identifying Multi-Omics Causers and Causal Pathways for Complex Traits |
| Q38361348 | Identifying the biological basis of GWAS hits for endometriosis. |
| Q38889051 | Immunogenomics of gastrointestinal nematode infection in ruminants - breeding for resistance to produce food sustainably and safely |
| Q36502969 | Impact of single-nucleotide polymorphisms on radiation pneumonitis in cancer patients |
| Q47994728 | Improving Disease Prediction by Incorporating Family Disease History in Risk Prediction Models with Large-Scale Genetic Data |
| Q41887939 | Imputation-based assessment of next generation rare exome variant arrays |
| Q30731532 | Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial) |
| Q46725769 | Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects |
| Q31116483 | Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients |
| Q61855138 | Insights into genetics, human biology and disease gleaned from family based genomic studies |
| Q64041297 | Insights into genetics, human biology and disease gleaned from family based genomic studies |
| Q34021782 | Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis |
| Q34762110 | Integrating genetics and social science: genetic risk scores |
| Q37054427 | Integrative analysis of cancer genes in a functional interactome |
| Q52373176 | Integrative omics for health and disease. |
| Q89107347 | Leveraging Ancestral Heterogeneity to Map Shared Genetic Risk Loci in Pediatric Steroid-Sensitive Nephrotic Syndrome |
| Q35559481 | Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP. |
| Q38255751 | MICA SNPs and the NKG2D system in virus-induced HCC. |
| Q36129109 | MaGelLAn 1.0: a software to facilitate quantitative and population genetic analysis of maternal inheritance by combination of molecular and pedigree information. |
| Q64111513 | Machine Learning SNP Based Prediction for Precision Medicine |
| Q37182897 | Machine learning, statistical learning and the future of biological research in psychiatry |
| Q35915068 | Mechanisms of Jak/STAT signaling in immunity and disease |
| Q38795760 | Microbial genome-wide association studies: lessons from human GWAS. |
| Q38755164 | Molecular Subtypes Improve Prognostic Value of International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Model |
| Q35626453 | Molecular basis and genetic predisposition to intracranial aneurysm |
| Q38188056 | Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies |
| Q30277960 | Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol |
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| Q51041886 | Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. |
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| Q26799197 | Opportunities and Challenges of Genotyping Patients With Nephrotic Syndrome in the Genomic Era |
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| Q31119292 | Pathway-Informed Classification System (PICS) for Cancer Analysis Using Gene Expression Data |
| Q37679140 | Personality traits and vulnerability or resilience to substance use disorders. |
| Q38749985 | Personalized Therapy of Hypertension: the Past and the Future |
| Q38756015 | Personalized medicine: Genetic risk prediction of drug response |
| Q41945248 | Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits |
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| Q49485833 | Prospective association of a genetic risk score with major adverse cardiovascular events in patients with coronary artery disease. |
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| Q50659753 | Systems Genetic Analysis in GeneNetwork.org. |
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| Q53376999 | Targeting microglia for the treatment of Alzheimer's Disease. |
| Q35802177 | Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic |
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| Q37403131 | The future for genetic studies in reproduction. |
| Q53818766 | The future of genomic testing in primary care: the changing face of personalized medicine. |
| Q36679858 | The hallmarks of premalignant conditions: a molecular basis for cancer prevention |
| Q58786509 | The impact of genome-wide association studies on biomedical research publications |
| Q33613854 | The impact of rare and low-frequency genetic variants in common disease |
| Q38786667 | The importance of p53 pathway genetics in inherited and somatic cancer genomes. |
| Q38617120 | The role of epigenetics in genetic and environmental epidemiology |
| Q38806240 | The statistical properties of gene-set analysis |
| Q28545045 | The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes |
| Q55304235 | Toward achieving precision health. |
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| Q47852851 | Updates in Lupus Genetics |
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