Polygenic Epidemiology

scientific article

Polygenic Epidemiology is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/GEPI.21966
P3181OpenCitations bibliographic resource ID2426963
P932PMC publication ID4982028
P698PubMed publication ID27061411

P50authorFrank DudbridgeQ60878633
P2093author name stringFrank Dudbridge
P2860cites workHeritability in the genomics era — concepts and misconceptionsQ22122010
Genetic studies of body mass index yield new insights for obesity biologyQ22305005
Biological insights from 108 schizophrenia-associated genetic lociQ24561833
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysisQ24597718
Five years of GWAS discoveryQ24610574
Common polygenic variation contributes to risk of schizophrenia and bipolar disorderQ28250609
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery diseaseQ28267020
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPsQ28296286
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexQ29547208
Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”Q61865038
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosisQ37619291
Bringing genome-wide association findings into clinical use.Q38120138
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysisQ39313673
A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a TraitQ39334653
Linkage strategies for genetically complex traits. I. Multilocus modelsQ40623210
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regressionQ40862437
Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effectsQ41511077
Prediction of individual genetic risk to prostate cancer using a polygenic scoreQ41584352
Using multiple genetic variants as instrumental variables for modifiable risk factorsQ41931960
Genome-wide efficient mixed-model analysis for association studiesQ41961596
Use of allele scores as instrumental variables for Mendelian randomizationQ42970966
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritisQ44921278
The heritability of prostate cancer—letterQ46112463
Celebrating the 30th anniversary of genetic epidemiology: how to define our scope?Q48072440
Common SNPs explain a large proportion of the heritability for human heightQ29547221
Personal genomes: The case of the missing heritabilityQ29614582
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation studyQ29615729
Prediction of total genetic value using genome-wide dense marker mapsQ29619613
Mendelian randomization of blood lipids for coronary heart diseaseQ30407506
Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.Q30798286
Accuracy of predicting the genetic risk of disease using a genome-wide approachQ33375729
Prediction and interaction in complex disease genetics: experience in type 1 diabetesQ33479555
Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to comeQ33772946
A population genetic signal of polygenic adaptationQ34015195
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genesQ34115258
MultiBLUP: improved SNP-based prediction for complex traitsQ34153795
Predicting human height by Victorian and genomic methodsQ34326904
Power and predictive accuracy of polygenic risk scores.Q34337027
Prediction of individual genetic risk to disease from genome-wide association studiesQ34676890
Polygenic dissection of the bipolar phenotypeQ34729917
Most common 'sporadic' cancers have a significant germline genetic componentQ34736858
Genome partitioning of genetic variation for complex traits using common SNPsQ34973837
Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease riskQ34988777
Mining the human phenome using allelic scores that index biological intermediatesQ35034381
Genomic inflation factors under polygenic inheritanceQ35108650
Massively expedited genome-wide heritability analysis (MEGHA).Q35134802
Sixty-five common genetic variants and prediction of type 2 diabetesQ35532317
Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture modelQ35596725
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosisQ35602297
Mendelian Randomization Study of Body Mass Index and Colorectal Cancer RiskQ35815677
LD Score regression distinguishes confounding from polygenicity in genome-wide association studiesQ35831121
Mammographic breast density and breast cancer: evidence of a shared genetic basisQ36043843
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian RandomizationQ36276540
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association studyQ36468290
Genome partitioning of genetic variation for height from 11,214 sibling pairsQ36492176
Prediction of breast cancer risk based on profiling with common genetic variantsQ36583004
An atlas of genetic correlations across human diseases and traitsQ36701237
Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studiesQ37059182
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectgeneticsQ7162
epidemiologyQ133805
biomedical investigative techniqueQ66648976
multifactorial inheritanceQ67200773
P304page(s)268-272
P577publication date2016-04-07
2016-05-01
P1433published inGenetic EpidemiologyQ5532864
P1476titlePolygenic Epidemiology
P478volume40

Reverse relations

cites work (P2860)
Q92066484A flexible and parallelizable approach to genome-wide polygenic risk scores
Q57050769A polygenic p factor for major psychiatric disorders
Q96822534A systematic review of gene-by-intervention studies of alcohol and other substance use
Q52372349A tutorial on conducting genome-wide association studies: Quality control and statistical analysis.
Q98465031Association Between FoxO1, A2M, and TGF-β1, Environmental Factors, and Major Depressive Disorder
Q47425592Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder
Q55463277Cardiovascular Risk Stratification: From Phenotype to Genotype?
Q64058600Combining Sparse Group Lasso and Linear Mixed Model Improves Power to Detect Genetic Variants Underlying Quantitative Traits
Q50301210Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Q47094762Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies
Q89798942Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models
Q92008549Exome chip-driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups
Q39448284Genes, Environments, and Sex Differences in Alcohol Research
Q90480219Genetic Variants Detection Based on Weighted Sparse Group Lasso
Q93154106Genetic risk, body mass index, and weight control behaviors: Unlocking the triad
Q90618568Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education
Q92599298Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects
Q38752201Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers
Q46419306Genomics of Posttraumatic Stress Disorder: Sequencing Stress and Modeling Misfortune.
Q41978253Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations
Q42145797Improving polygenic risk prediction from summary statistics by an empirical Bayes approach
Q90453214Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome-wide association studies
Q40259459Letter to the Editor: Posttraumatic stress disorder has genetic overlap with cardiometabolic traits.
Q90341162Missing single nucleotide polymorphisms in Genetic Risk Scores: A simulation study
Q38840593Mortality selection in a genetic sample and implications for association studies
Q47703297No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease
Q50100394Novel Insights into the Pathogenesis of Monogenic Congenital Anomalies of the Kidney and Urinary Tract.
Q54079923On the use of genetic risk scores to predict cardiovascular disease in the general population.
Q90685954Polygenic Risk Scores for Psychiatric Disorders Reveal Novel Clues About the Genetics of Disordered Gambling
Q52630895Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences.
Q92859182Polygenic risk scores in psychiatry: Will they be useful for clinicians?
Q38798713Polygenic scores via penalized regression on summary statistics
Q57471049Prediction of treatment response in rheumatoid arthritis patients using genome-wide SNP data
Q47409320Predictive accuracy of combined genetic and environmental risk scores
Q58564518Provider bias as a function of patient genotype: polygenic score analysis among diabetics from the Health and Retirement Study
Q91989992Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies
Q91337965Rigor and reproducibility in genetic research on eating disorders
Q61755960The Genetic Sphygmomanometer: an argument for routine genome-wide genotyping in the population and a new view on its use to inform clinical practice
Q57789969The Role of Emergence in Genetically Informed Relationships Research: A Methodological Analysis
Q47619056The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders.
Q57170901Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density
Q97692972Tutorial: a guide to performing polygenic risk score analyses

Search more.