Abstract is: Frank Dudbridge is Professor of Statistical Genetics in the Department of Health Sciences at the University of Leicester, where he has worked since 2016. His research focuses on the fields of statistical genetics and genetic epidemiology as they relate to common human diseases. Before joining the University of Leicester, he served first as a senior statistician at the MRC Biostatistics Unit at the University of Cambridge, then as Reader and Professor of Statistical Genetics at the London School of Hygiene and Tropical Medicine.
| human | Q5 |
| P2671 | Google Knowledge Graph ID | /g/11f0lw6z44 |
| P496 | ORCID iD | 0000-0002-8817-8908 |
| P69 | educated at | Imperial College London | Q189022 |
| King's College London | Q245247 | ||
| P108 | employer | University of Oxford | Q34433 |
| University of Cambridge | Q35794 | ||
| University of California, San Diego | Q622664 | ||
| London School of Hygiene & Tropical Medicine | Q1126189 | ||
| University of Leicester | Q1333399 | ||
| University of Bath | Q1422458 | ||
| MRC Biostatistics Unit | Q30280314 | ||
| P735 | given name | Frank | Q220546 |
| Frank | Q220546 | ||
| P106 | occupation | researcher | Q1650915 |
| P21 | sex or gender | male | Q6581097 |
| Q37169873 | 9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium |
| Q24646314 | A HaemAtlas: characterizing gene expression in differentiated human blood cells |
| Q57316463 | A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects |
| Q92066484 | A flexible and parallelizable approach to genome-wide polygenic risk scores |
| Q33795146 | A flexible model for association analysis in sibships with missing genotype data |
| Q46017492 | A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. |
| Q34160962 | A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis |
| Q42418628 | A note on permutation tests in multistage association scans. |
| Q41738233 | A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis |
| Q88233265 | Accuracy of Gene Scores when Pruning Markers by Linkage Disequilibrium |
| Q39313673 | Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis |
| Q57719174 | Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation |
| Q40189510 | An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD. |
| Q44020514 | Application of the optimal discovery procedure to genetic case-control studies: comparison with p values and asymptotic Bayes factors. |
| Q59768967 | Are Your Covariates Under Control? How Normalization Can Re-introduce Covariate Effects |
| Q35144308 | Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? |
| Q88506822 | Are your covariates under control? How normalization can re-introduce covariate effects |
| Q35633247 | Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs |
| Q28655857 | Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data |
| Q33490625 | Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia |
| Q92528135 | Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events |
| Q31172041 | Association of common genetic variants with lipid traits in the Indian population |
| Q46531741 | Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. |
| Q34562472 | Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs |
| Q35113828 | Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier |
| Q101564213 | Author Correction: Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival |
| Q26849726 | Candidate gene-environment interactions in breast cancer |
| Q39271487 | Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI. |
| Q55064805 | Capture Hi-C identifies putative target genes at 33 breast cancer risk loci. |
| Q63352885 | Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design |
| Q30252417 | Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis |
| Q90683722 | Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts |
| Q112297529 | Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment |
| Q31031884 | Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods |
| Q47397596 | Commentary: Tobacco consumption and body weight: Mendelian randomization across a range of exposure |
| Q44498564 | Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro |
| Q24641881 | Common variants on chromosome 6p22.1 are associated with schizophrenia |
| Q31079387 | Comparison of methods for competitive tests of pathway analysis |
| Q33688537 | Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia. |
| Q35029582 | Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal |
| Q39217627 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects |
| Q28304430 | Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications |
| Q37571557 | Copy number variation of the APC gene is associated with regulation of bone mineral density |
| Q96773652 | Criteria for evaluating risk prediction of multiple outcomes |
| Q36696957 | Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer |
| Q40278898 | Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms |
| Q36440632 | Detecting multiple associations in genome-wide studies |
| Q37202894 | Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study |
| Q115022040 | Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1L |
| Q42533237 | Erratum: Whole-genome sequence-based analysis of thyroid function |
| Q34057960 | Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases |
| Q46263944 | Estimation of a significance threshold for epigenome-wide association studies |
| Q24289532 | Estimation of significance thresholds for genomewide association scans |
| Q81105171 | Evaluation of Nyholt's procedure for multiple testing correction |
| Q36686448 | Evaluation of seven common lipid associated loci in a large Indian sib pair study |
| Q52374241 | Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts. |
| Q82865348 | Family-based association studies |
| Q42411960 | Fast and robust association tests for untyped SNPs in case-control studies |
| Q35524465 | Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. |
| Q30487560 | Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins |
| Q47845822 | Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis |
| Q34146836 | Gene-environment dependence creates spurious gene-environment interaction |
| Q40610642 | Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam |
| Q28251861 | Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome |
| Q38058276 | Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis |
| Q53172448 | Genetic determinants of major blood lipids in Pakistanis compared with Europeans. |
| Q39579388 | Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores |
| Q102388878 | Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women |
| Q61805607 | Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget's disease of bone |
| Q28296286 | Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs |
| Q34031201 | Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men |
| Q35179897 | Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study |
| Q28297287 | Genome-wide association analysis identifies 13 new risk loci for schizophrenia |
| Q38803986 | Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation |
| Q29417080 | Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms |
| Q101133349 | Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival |
| Q35934634 | Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density |
| Q57697186 | Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes |
| Q117813333 | Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes |
| Q35065253 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials |
| Q59200321 | Haplotype tagging for the identification of common disease genes |
| Q36031139 | Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents |
| Q47312439 | How many cases of disease in a pedigree imply familial disease? |
| Q36719026 | Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis |
| Q49547935 | Impact of Selection Bias on Estimation of Subsequent Event Risk. |
| Q51914983 | Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations. |
| Q111312503 | Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia |
| Q57309613 | Interpreting Association Signals |
| Q31151241 | Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data |
| Q30670348 | Linkage analysis of Genetic Analysis Workshop 12 simulated data based on affected individuals only. |
| Q40593467 | Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes |
| Q51825592 | Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort. |
| Q57309615 | List of Contributors |
| Q111660895 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia |
| Q47277471 | Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus |
| Q37398952 | Marginal role for 53 common genetic variants in cardiovascular disease prediction |
| Q57304594 | Maximizing association statistics over genetic models |
| Q38939614 | Mendelian Randomisation study of the influence of eGFR on coronary heart disease |
| Q30407506 | Mendelian randomization of blood lipids for coronary heart disease |
| Q47290398 | Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors |
| Q30988023 | New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis |
| Q91908132 | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries |
| Q63352630 | New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries |
| Q33200785 | Pelican: pedigree editor for linkage computer analysis. |
| Q36724236 | Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis |
| Q26750522 | Polygenic Epidemiology |
| Q90766347 | Polygenic Mendelian Randomization |
| Q34577325 | Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome. |
| Q46772126 | Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome. |
| Q28681745 | Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium |
| Q34337027 | Power and predictive accuracy of polygenic risk scores. |
| Q36583004 | Prediction of breast cancer risk based on profiling with common genetic variants |
| Q47409320 | Predictive accuracy of combined genetic and environmental risk scores |
| Q52007500 | Rank truncated product of P-values, with application to genomewide association scans. |
| Q87154706 | Re: Is the Risk Difference Really a More Heterogeneous Measure? |
| Q61865038 | Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects” |
| Q37435432 | Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor |
| Q34434004 | Research review: Polygenic methods and their application to psychiatric traits |
| Q35794330 | Retrospective analysis of the quality of reports by author-suggested and non-author-suggested reviewers in journals operating on open or single-blind peer review models |
| Q35532317 | Sixty-five common genetic variants and prediction of type 2 diabetes |
| Q92522162 | Subsequent Event Risk in Individuals With Established Coronary Heart Disease |
| Q34769379 | Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits |
| Q35864053 | The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis |
| Q34374101 | Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function |
| Q36507059 | Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon |
| Q38996222 | Two novel pathway analysis methods based on a hierarchical model. |
| Q38849881 | Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1. |
| Q34439389 | Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C. |
| Q41894536 | Unbiased estimation of odds ratios: combining genomewide association scans with replication studies. |
| Q39368271 | Utilising family-based designs for detecting rare variant disease associations |
| Q38719386 | Variants in the fetal genome near FLT1 are associated with risk of preeclampsia |
| Q33695782 | What role for genetics in the prediction of multiple sclerosis? |
| Q30316724 | Whole-genome sequence-based analysis of thyroid function. |
| Frank Dudbridge | wikipedia |
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