Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection

scientific article published on 13 August 2013

Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1037242959
P356DOI10.1007/S11481-013-9491-3
P932PMC publication ID3889225
P698PubMed publication ID23943280
P5875ResearchGate publication ID255952858

P50authorRichard D. SmithQ7325058
Henrik ZetterbergQ6252048
Dietmar FuchsQ38801487
Magnus GisslénQ90302675
Thomas E AngelQ93154621
Lars HagbergQ97650293
Serena SpudichQ114411897
Richard W PriceQ124366832
Julia PetersonQ124366838
Jon M JacobsQ124366849
Joseph N. BrownQ124366850
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Cerebrospinal fluid and plasma biomarkers in Alzheimer diseaseQ34098866
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HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER StudyQ34370880
Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF.Q34402201
Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohortQ34497788
Differential effect of type I and type II interferons on neopterin production and amino acid metabolism in human astrocyte-derived cells.Q39985237
HIV-1 viral load and clinical outcome: review of recent studies.Q41694976
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Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infectionQ43477829
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Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.Q44028578
Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementiaQ44253971
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Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center GroupQ45759166
Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infectionQ46520858
Virologic, immunologic, and immune activation markers as predictors of HIV-associated weight loss prior to AIDS. Multicenter AIDS Cohort StudyQ47249301
Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replicationQ47672132
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Cerebrospinal fluid markers that predict SIV CNS diseaseQ48957436
HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatmentQ34644242
Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infectionQ34740804
Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected SubjectsQ34792090
Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burdenQ35164448
Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1 infection or immunoactivation in subjects on suppressive therapyQ35532868
Incidence of post-dural puncture headache in research volunteersQ35552718
Updated research nosology for HIV-associated neurocognitive disordersQ35755761
The cerebrospinal fluid proteome in HIV infection: change associated with disease severityQ35965332
Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infectionQ36060674
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Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infectionQ36796560
Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapyQ36854127
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Biomarkers of HIV-1 CNS infection and injuryQ36984776
Defining and evaluating HIV-related neurodegenerative disease and its treatment targets: a combinatorial approach to use of cerebrospinal fluid molecular biomarkersQ37015519
Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapyQ37066971
The role of HIV in serious diseases other than AIDS.Q37186467
Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infectionQ37351669
Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral loadQ37436136
CSF biomarkers of Alzheimer disease in HIV-associated neurologic diseaseQ37465068
Antiretroviral drug treatment of CNS HIV-1 infectionQ37967355
HIV and inflammation: mechanisms and consequencesQ38005046
Antiretroviral treatment reduces increased CSF neurofilament protein (NFL) in HIV-1 infectionQ38429930
CSF neurofilament protein (NFL) -- a marker of active HIV-related neurodegeneration.Q38433078
Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapyQ38460449
Changing incidence of central nervous system diseases in the EuroSIDA cohortQ38479888
HIV-1 chemokine coreceptor utilization in paired cerebrospinal fluid and plasma samples: a survey of subjects with viremiaQ39483826
The AIDS dementia complexQ39535506
The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complexQ39628230
Amyloid-related biomarkers and axonal damage proteins in parkinsonian syndromesQ39713596
Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trialQ50457244
Incidence and impact on mortality of severe neurocognitive disorders in persons with and without HIV infection: a Danish nationwide cohort study.Q50553161
Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections.Q53333738
Patients with Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases Have Increased Levels of Neurofilament Protein in CSFQ55952248
Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral TherapyQ57176735
Cognitive dysfunction in HIV patients despite long-standing suppression of viremiaQ58074796
Elevated levels of tumor necrosis factor (TNF) in the cerebrospinal fluid from patients with HIV-associated neurological disordersQ58480109
Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task ForceQ70181586
Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. AIDS Clinical Trials GroupQ70706038
Positive and sustained effects of highly active antiretroviral therapy on HIV-1-associated neurocognitive impairmentQ73064672
Cerebrospinal fluid S-100beta and its relationship with AIDS dementia complexQ74532087
Cerebrospinal fluid viral load, intrathecal immunoactivation, and cerebrospinal fluid monocytic cell count in HIV-1 infectionQ78066974
Elevated cerebrospinal fluid neurofilament light protein concentrations predict the development of AIDS dementia complexQ80306158
Cerebrospinal fluid interferon-gamma-inducible protein 10 (IP-10, CXCL10) in HIV-1 infectionQ81037707
Cerebrospinal fluid markers in central nervous system HIV infection and AIDS dementia complexQ82029827
Measurement of soluble inflammatory mediators in cerebrospinal fluid of human immunodeficiency virus-positive patients at distinct stages of infection by solid-phase protein arrayQ82206160
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcerebrospinal fluidQ54196
biomarkerQ864574
AIDS dementia complexQ3435504
P304page(s)1147-1158
P577publication date2013-08-13
2013-12-01
P1433published inJournal of Neuroimmune PharmacologyQ6295645
P1476titleApproach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection
P478volume8

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cites work (P2860)
Q40431064A comparison of HMGB1 concentrations between cerebrospinal fluid and blood in patients with neurological disease.
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Q37513800Biomarkers for NeuroAIDS: recent progress in the field
Q40455681Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection.
Q34776835Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection
Q33924678Changes in PINCH levels in the CSF of HIV+ individuals correlate with hpTau and CD4 count
Q64974601Clinical characteristics and cerebro-spinal fluid cytokine changes in patients with acquired immunodeficiency syndrome and central nervous system infection.
Q35219829Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection
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Q33995713Evolving character of chronic central nervous system HIV infection
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Q35154529Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders
Q36072424Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid.
Q38832560Neurologic Complications in Treated HIV-1 Infection
Q40607244No support for premature central nervous system aging in HIV-1 when measured by cerebrospinal fluid phosphorylated tau (p-tau).
Q33633451Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders
Q26824179Role of HIV in amyloid metabolism
Q35996619Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
Q40437527Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-related neuropathological conditions.