| scholarly article | Q13442814 |
| P50 | author | Heinz Wiendl | Q27583547 |
| Catharina C Gross | Q83479317 | ||
| Sven G Meuth | Q88461559 | ||
| Tilman Schneider-Hohendorf | Q48938829 | ||
| P2093 | author name string | Hubertus Lohmann | |
| Ingo W Husstedt | |||
| Doris Reichelt | |||
| Oliver M Grauer | |||
| Andreas Schulte-Mecklenbeck | |||
| Ute Grüneberg | |||
| P2860 | cites work | The neuropathogenesis of AIDS | Q28300983 |
| The CD4:CD8 ratio is associated with markers of age-associated disease in virally suppressed HIV-infected patients with immunological recovery | Q29307877 | ||
| PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression | Q29618956 | ||
| T cell exhaustion | Q29620463 | ||
| High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication | Q33406497 | ||
| Clinical, immunological and treatment-related factors associated with normalised CD4+/CD8+ T-cell ratio: effect of naïve and memory T-cell subsets | Q33591190 | ||
| HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality | Q33618542 | ||
| Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion | Q33882912 | ||
| Cognitive dysfunction in HIV patients despite long-standing suppression of viremia | Q58074796 | ||
| Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease | Q73470103 | ||
| Highly active antiretroviral therapy for patients with AIDS dementia complex: effect on MR imaging findings and clinical course | Q73715294 | ||
| HIV-associated neurocognitive disorder. | Q33939729 | ||
| Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression | Q34004816 | ||
| Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection | Q34072838 | ||
| Diffusion tensor and volumetric magnetic resonance measures as biomarkers of brain damage in a small animal model of HIV. | Q34075695 | ||
| HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study | Q34370880 | ||
| Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort | Q34497788 | ||
| Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction | Q34570127 | ||
| PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors | Q34574649 | ||
| Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection | Q34589265 | ||
| Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. | Q34891171 | ||
| Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection | Q35175447 | ||
| Neurocognitive impairment in HIV-infected naïve patients with advanced disease: the role of virus and intrathecal immune activation. | Q35872249 | ||
| Defining and evaluating HIV-related neurodegenerative disease and its treatment targets: a combinatorial approach to use of cerebrospinal fluid molecular biomarkers | Q37015519 | ||
| Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy | Q37066971 | ||
| Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection | Q37351669 | ||
| CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy | Q37402458 | ||
| Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection | Q37467991 | ||
| Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease | Q37499490 | ||
| Increased risk of serious non-AIDS-related events in HIV-infected subjects on antiretroviral therapy associated with a low CD4/CD8 ratio. | Q37534052 | ||
| HIV and neurocognitive dysfunction | Q38122104 | ||
| Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection | Q38128778 | ||
| Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh | Q39351562 | ||
| Influence of HAART on HIV-related CNS disease and neuroinflammation. | Q40411104 | ||
| HIV dementia. Incidence and risk factors. | Q40718431 | ||
| Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study. | Q41063277 | ||
| VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells | Q41966039 | ||
| Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection | Q41978842 | ||
| Spontaneous control of HIV replication, but not HAART-induced viral suppression, is associated with lower activation of immune cells | Q42224555 | ||
| Specific loss of cellular L-selectin on CD4(+) T cells is associated with progressive multifocal leukoencephalopathy development during HIV infection. | Q42242256 | ||
| The CD4/CD8 ratio as a marker T-cell activation, senescence and activation/exhaustion in treated HIV-infected children and young adults | Q42273640 | ||
| Persisting inflammation and chronic immune activation but intact cognitive function in HIV-infected patients after long-term treatment with combination antiretroviral therapy | Q42275845 | ||
| Cerebral signal intensity abnormalities on T2-weighted MR images in HIV patients with highly active antiretroviral therapy: relationship with clinical parameters and interval changes | Q42490532 | ||
| PD-1 and its ligand PD-L1 are progressively up-regulated on CD4 and CD8 T-cells in HIV-2 infection irrespective of the presence of viremia. | Q43698833 | ||
| The prevalence and incidence of neurocognitive impairment in the HAART era. | Q44520627 | ||
| The CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression | Q44701988 | ||
| Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction | Q45402229 | ||
| Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy | Q46812278 | ||
| Cognitive impairment in HIV infection is associated with MRI and CSF pattern of neurodegeneration | Q48323194 | ||
| Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF. | Q48789449 | ||
| P433 | issue | 9 | |
| P921 | main subject | cerebrospinal fluid | Q54196 |
| P304 | page(s) | 906-919 | |
| P577 | publication date | 2015-08-18 | |
| P1433 | published in | Annals of clinical and translational neurology | Q27725312 |
| P1476 | title | Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid | |
| P478 | volume | 2 |
| Q40463006 | A decreasing CD4/CD8 ratio over time and lower CSF-penetrating antiretroviral regimens are associated with a higher risk of neurocognitive deterioration, independently of viral replication. |
| Q90636595 | Altered Brain Function in Young HIV Patients with Syphilis Infection: A Voxel-Wise Degree Centrality Analysis |
| Q40262441 | Blood-Brain Barrier Disruption Is Initiated During Primary HIV Infection and Not Rapidly Altered by Antiretroviral Therapy |
| Q38892073 | CROI 2016: Neurologic Complications of HIV Infection. |
| Q54218501 | Characterization of Cellular Immune Responses in Thai Individuals with and without HIV-Associated Neurocognitive Disorders. |
| Q39417239 | Childhood maltreatment and HIV-associated neurocognitive disorders share similar pathophysiology: a potential sensitisation mechanism? |
| Q38836472 | Cognitive Impairment and Persistent CNS Injury in Treated HIV. |
| Q94544520 | Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV |
| Q64076635 | Glial Cell Expression of PD-L1 |
| Q88660087 | HIV-associated neurocognitive disorder |
| Q51743775 | Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection. |
| Q38433342 | High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection |
| Q38694693 | Immune activation in the central nervous system throughout the course of HIV infection |
| Q38887687 | Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activation |
| Q52774286 | Neurological Complications of HIV Infection. |
| Q89483369 | Peripheral and cerebrospinal fluid immune activation and inflammation in chronically HIV-infected patients before and after virally suppressive combination antiretroviral therapy (cART) |
| Q59134956 | Single-cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid during virologically suppressed HIV |
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