Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction

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Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1033121719
P356DOI10.1080/13550280701327038
P698PubMed publication ID17613711

P2093author name stringMahendra Kumar
Adarsh M Kumar
Louis Gonzalez
Benny Fernandez
Irina Borodowsky
P2860cites workReal-time PCR in virologyQ24514920
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/mlQ24545015
A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected childrenQ24620746
Pathogenesis of human immunodeficiency virus infectionQ24634681
Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymeraseQ28291219
CCR3 and CCR5 are co-receptors for HIV-1 infection of microgliaQ28303212
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study InvestigatorsQ29547281
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infectionQ29619738
Gene expression profiling in the post-mortem human brain--no cause for dismay.Q30996882
Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.Q33649460
Ultrasensitive reverse transcription-PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasmaQ33678850
Chemokine receptors and virus entry in the central nervous systemQ33797103
Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapyQ33932746
Quantification of human immunodeficiency virus type 1 proviral load by a TaqMan real-time PCR assayQ33971820
Pathways to neuronal injury and apoptosis in HIV-associated dementia.Q34223078
In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissuesQ35878219
Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: association with dementia and multinucleated giant cells in the brains of patients with AIDS.Q35880742
Transendothelial migration of monocytes: the underlying molecular mechanisms and consequences of HIV-1 infectionQ36297771
Evidence of CNS impairment in HIV infection: clinical, neuropsychological, EEG, and MRI/MRS study.Q36318621
Neuropathology of Human Immunodeficiency Virus InfectionQ36476918
Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequencesQ36637273
Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patientsQ37400137
The latent reservoir for HIV-1 in resting CD4+ T cells: a barrier to cureQ37446807
Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatmentQ37492836
Human immunodeficiency virus (HIV)-induced disease of the central nervous system: pathology and implications for pathogenesisQ38266133
Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: application to acute retroviral infection.Q38311594
The role of mRNA and protein stability in gene expressionQ38696474
HIV-1-related neurological disease.Q38920918
Expression directed from HIV long terminal repeats in the central nervous system of transgenic miceQ38953163
Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brainQ39310058
Pre‐and Postmortem Influences on Brain RNAQ40487622
Neuroglial-specific factors and the regulation of retrovirus transcriptionQ40603318
Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndromeQ40604776
Accumulation of unintegrated circular viral DNA in monocytes and growth-arrested T cells following infection with HIV-1.Q40701543
Residual HIV-RNA levels persist for up to 2.5 years in peripheral blood mononuclear cells of patients on potent antiretroviral therapyQ40751379
Neuronal loss in the frontal cortex in HIV infectionQ41151569
Chemokine receptors: gateways to inflammation and infectionQ41193992
Characterisation of messenger RNA extracted post-mortem from the brains of schizophrenic, depressed and control subjectsQ41893032
Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical methodQ42465505
Quantification of human immunodeficiency virus type 1 proviral DNA by the TaqMan real-time PCR assayQ42789109
The National NeuroAIDS Tissue Consortium: a new paradigm in brain banking with an emphasis on infectious diseaseQ43639344
High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patientsQ44019946
Distribution of brain HIV load in AIDS.Q44706094
CNS as an HIV-1 reservoir; BBB and drug deliveryQ44823285
HIV in the brain: RNA levels and patterns of zidovudine resistanceQ45027990
Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patientsQ45415194
Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samplesQ45744551
Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brainQ45759163
Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center GroupQ45759166
Cognitive performance and regional brain volume in human immunodeficiency virus type 1 infectionQ45770654
Magnetic resonance imaging morphometric analysis of cerebral volume loss in human immunodeficiency virus infection. The HNRC GroupQ45773831
Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects.Q45775929
Application of branched DNA signal amplification to monitor human immunodeficiency virus type 1 burden in human plasmaQ45782351
Cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) p24 antigen levels in HIV-1-related dementiaQ45783177
Spectrum of human immunodeficiency virus-associated neocortical damageQ45871285
Brain viral burden in HIV infection.Q46003548
Neocortical damage during HIV infectionQ46301054
Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridizationQ46960543
Early penetration of the blood-brain-barrier by HIV.Q48125248
The AIDS dementia complex: II. NeuropathologyQ48340087
Extensive postmortem stability of RNA from rat and human brainQ48423893
Treating AIDS dementiaQ48684058
A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitisQ48743313
Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid.Q54036208
Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavirQ57176775
The isolation and in vitro translation of undegraded messenger RNAs from human postmortem brainQ70932306
Neurological complications of HIV infectionQ71264589
Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistryQ71467046
The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteinsQ73142043
HIV mediates a productive infection of the brainQ73145576
Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapyQ74770724
P433issue3
P304page(s)210-224
P577publication date2007-06-01
P1433published inJournal of NeuroVirologyQ6295640
P1476titleHuman immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction
P478volume13

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cites work (P2860)
Q92290404An Omics Approach to Extracellular Vesicles from HIV-1 Infected Cells
Q54209535Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells.
Q40391119Assays for precise quantification of total (including short) and elongated HIV-1 transcripts.
Q57793028BCL6 Inhibitor-mediated Downregulation of pSAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation
Q47666097Brain Structural Changes following HIV Infection: Meta-Analysis.
Q34720281Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient
Q38626559Cognitive impairment in HIV and HCV co-infected patients: a systematic review and meta-analysis
Q58240326Cognitive impairment in HIV and HCV co-infected patients: a systematic review and meta-analysis
Q34083315Comparison of HIV DNA and RNA in gut-associated lymphoid tissue of HIV-infected controllers and noncontrollers
Q34736406Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy
Q40447357Deformed Subcortical Structures Are Related to Past HIV Disease Severity in Youth With Perinatally Acquired HIV Infection.
Q89637539Differences in Transcriptional Dynamics Between T-cells and Macrophages as Determined by a Three-State Mathematical Model
Q92676513Different roles of frontal versus striatal atrophy in HIV-associated neurocognitive disorders
Q38930864Discordance between peripheral and colonic markers of inflammation during suppressive ART
Q64076926Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate
Q37513129Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques
Q34196506Drugs of abuse, dopamine, and HIV-associated neurocognitive disorders/HIV-associated dementia
Q37094265Early detection of simian immunodeficiency virus in the central nervous system following oral administration to rhesus macaques
Q34252905Early microstructural white matter changes in patients with HIV: a diffusion tensor imaging study
Q35965672Early minocycline treatment prevents a decrease in striatal dopamine in an SIV model of HIV-associated neurological disease
Q34141266Elevated brain monoamine oxidase activity in SIV- and HIV-associated neurological disease
Q57815643Exploration of the involvement of LncRNA in HIV-associated encephalitis using bioinformatics
Q39031641Genetic diversity and proviral DNA load in different neural compartments of HIV-1 subtype C infection
Q41107466HIV encephalopathy: glial activation and hippocampal neuronal apoptosis, but limited neural repair.
Q59357751HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy
Q45954015HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.
Q55309956HIV-1 proteins dysregulate motivational processes and dopamine circuitry.
Q36009246HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment
Q45370440Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance
Q45383832Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains
Q47600062Immune Interventions to Eliminate the HIV Reservoir
Q37181324Increases in brain white matter abnormalities and subcortical gray matter are linked to CD4 recovery in HIV infection
Q58557904Inflammation Relates to Poorer Complex Motor Performance among Adults Living with HIV on Suppressive Antiretroviral Therapy
Q37399037Inhibition of GABAergic Neurotransmission by HIV-1 Tat and Opioid Treatment in the Striatum Involves μ-Opioid Receptors.
Q92803873Laboratory surrogate markers of residual HIV replication among distinct groups of individuals under antiretroviral therapy
Q47201399Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART.
Q59349953Low-frequency fluctuation characteristics in rhesus macaques with SIV infection: a resting-state fMRI study
Q90705114Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy
Q34988471Micro-structural brain alterations in aviremic HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field
Q37308125Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter
Q37698620Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system
Q48141474National Institute on Drug Abuse symposium report: drugs of abuse, dopamine, and HIV-associated neurocognitive disorders/HIV-associated dementia.
Q36072424Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid.
Q38879533Neuropharmacologic Approaches to Restore the Brain's Microenvironment.
Q33781978Pathogenesis of HIV in the central nervous system
Q38247035Pharmacokinetics and pharmacodynamics of antiretrovirals in the central nervous system
Q35018065Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers
Q37041173Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ-NF-κB signaling
Q99207830Recommendations for measuring HIV reservoir size in cure-directed clinical trials
Q39427179Role of microglia in methamphetamine-induced neurotoxicity
Q35125996Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
Q35242182SIV/macaque model of HIV infection in cocaine users: minimal effects of cocaine on behavior, virus replication, and CNS inflammation
Q35271996Select host restriction factors are associated with HIV persistence during antiretroviral therapy
Q33893665Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA
Q42482128Structural gray and white matter changes in patients with HIV.
Q28546901Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation
Q27316403TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
Q54982714Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS.
Q37187497The distribution of HIV DNA and RNA in cell subsets differs in gut and blood of HIV-positive patients on ART: implications for viral persistence
Q34818798The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial
Q43505499The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure.
Q53828206The role of catecholamines in HIV neuropathogenesis.
Q37055454Tissue reservoirs of HIV
Q42157707Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs
Q39077816Treating HIV Infection in the Central Nervous System
Q56893328Viral diseases of the central nervous system
Q34990422fMRI brain activation during a delay discounting task in HIV-positive adults with and without cocaine dependence

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