Pathogenesis of graft-versus-host disease: innate immunity amplifying acute alloimmune responses

scientific article published on 28 August 2013

Pathogenesis of graft-versus-host disease: innate immunity amplifying acute alloimmune responses is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1009114599
P356DOI10.1007/S12185-013-1421-X
P698PubMed publication ID23982970

P2093author name stringYoshinobu Maeda
P2860cites workIndoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethalityQ28509235
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responsesQ28588300
Molecular identification of a danger signal that alerts the immune system to dying cellsQ29619497
Divergence of quaternary structures among bacterial flagellar filamentsQ30446018
Heat shock protein 70: correlation of expression with degree of graft-versus-host response and clinical graft-versus-host disease1Q33193121
Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathiesQ33401314
Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantationQ33615249
Innate immunity and transplantation tolerance: the potential role of TLRs/NLRs in GVHDQ35084400
Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation modelQ35525740
Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantationQ35673668
Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunityQ35691842
Deficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host diseaseQ35995245
LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantationQ36028584
Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharideQ36078180
An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissuesQ36228795
Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantationQ36305350
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.Q36330867
Implications of TNF-α in the pathogenesis and management of GVHDQ36370782
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejectionQ36941127
Activation of the innate immune system by the endogenous ligand hyaluronanQ37228248
NOD2 regulates hematopoietic cell function during graft-versus-host diseaseQ37377427
Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host diseaseQ37388077
Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethalityQ37460355
The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancerQ37487325
Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptorsQ37665086
Improved outcome of hematopoietic SCT in patients with homozygous gene variant of Toll-like receptor 9.Q39878275
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantationQ40516766
Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R.Q42794018
MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host diseaseQ42966829
Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Q44848328
High-mobility group box 1 (HMGB1) as a master regulator of innate immunityQ45863504
Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in childrenQ46297998
Host dendritic cells alone are sufficient to initiate acute graft-versus-host diseaseQ47371499
The biology of graft-versus-host reactionsQ47809350
Association of HMGB1 polymorphisms with outcome after allogeneic hematopoietic cell transplantation.Q51785979
P2X7 receptor polymorphism and clinical outcomes in HLA-matched sibling allogeneic hematopoietic stem cell transplantation.Q53571198
Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Q54620738
Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.Q54636018
Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory CellsQ57447880
Salivary Proteomic Analysis and Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell TransplantationQ60464156
Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantationQ62658643
Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantationQ62658651
Association of TLR4 mutations and the risk for acute GVHD after HLA-matched-sibling hematopoietic stem cell transplantationQ74444949
Prevention of graft versus host disease by inactivation of host antigen-presenting cellsQ78016071
CD44-hyaluronic acid interactions mediate shear-resistant binding of lymphocytes to dermal endothelium in acute cutaneous GVHDQ79077287
"Secondary disease" of radiation chimeras: a syndrome due to lymphoid aplasiaQ79585828
Critical role of TLR9 in acute graft-versus-host diseaseQ79675206
No impact of NOD2/CARD15 on outcome after SCTQ80813551
HSP70-hom gene polymorphism in allogeneic hematopoietic stem-cell transplant recipients correlates with the development of acute graft-versus-host diseaseQ81628613
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontaminationQ82312167
Successful treatment of refractory acute GVHD complicated by severe intestinal transplant-associated thrombotic microangiopathy using recombinant thrombomodulinQ83286523
Steroid-refractory GVHD: T-cell attack within a vulnerable endothelial systemQ84260223
P433issue3
P921main subjectpathogenesisQ372016
P1104number of pages7
P304page(s)293-299
P577publication date2013-08-28
P1433published inInternational Journal of HematologyQ6051416
P1476titlePathogenesis of graft-versus-host disease: innate immunity amplifying acute alloimmune responses
P478volume98

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cites work (P2860)
Q41070167A donor thrombomodulin gene variation predicts graft-versus-host disease development and mortality after bone marrow transplantation.
Q38689056Associations between acute GVHD-related biomarkers and endothelial cell activation after allogeneic hematopoietic stem cell transplantation
Q39013210Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease.
Q91010169Effects of recombinant thrombomodulin on long-term prognosis after allogeneic hematopoietic stem cell transplantation
Q33618681Endothelial microparticles delivering microRNA-155 into T lymphocytes are involved in the initiation of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
Q55311740Eosinophils from Physiology to Disease: A Comprehensive Review.
Q44128066Guest editorial: new basic and clinical aspects of graft-versus-host disease: what can we do without ‘‘Doc’’ Brown’s help?
Q57466793Host MyD88 signaling protects against acute graft-versus-host disease after allogeneic bone marrow transplantation
Q57818274Infection Complications in Hematopoietic Stem Cells Transplant Recipients: Do Genetics Really Matter?
Q38309267Innate immunity for better or worse govern the allograft response
Q35587907Intestinal microbiota-related effects on graft-versus-host disease.
Q34487408Methotrexate for the Treatment of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.
Q38502469Non-HLA genomics: does it have a role in predicting haematopoietic stem cell transplantation outcome?
Q38753771Potential of glycosylation research in graft versus host disease after allogeneic hematopoietic stem cell transplantation
Q38416371Prophylactic and therapeutic treatment of graft-versus-host disease in Japan
Q50062411TAK1 inhibition ameliorates survival from graft-versus-host disease in an allogeneic murine marrow transplantation model
Q35609254The Free Radical Scavenger NecroX-7 Attenuates Acute Graft-versus-Host Disease via Reciprocal Regulation of Th1/Regulatory T Cells and Inhibition of HMGB1 Release.
Q59130037Toll-Like Receptor Stimulation by MicroRNAs in Acute Graft-vs.-Host Disease
Q40209654Toll-like receptor genetic variations in bone marrow transplantation.

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