NOD2 regulates hematopoietic cell function during graft-versus-host disease

scientific article published on 08 September 2009

NOD2 regulates hematopoietic cell function during graft-versus-host disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.20090623
P932PMC publication ID2757869
P698PubMed publication ID19737867
P5875ResearchGate publication ID26796710

P50authorMarcel R.M. van den BrinkQ17198821
P2093author name stringAmanda M Holland
Arnab Ghosh
George F Murphy
Odette M Smith
Chen Liu
Xin Liu
Robert R Jenq
Katharina Brandl
Il-Kang Na
Sydney X Lu
Olaf Penack
Nury Yim
Amy Cunningham-Bussel
Uttam Rao
P2860cites workA frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Tumor immunotherapy across MHC barriers using allogeneic T-cell precursorsQ24647124
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaBQ28142782
Signalling pathways and molecular interactions of NOD1 and NOD2Q28298636
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitisQ28511027
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tractQ28587612
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responsesQ28588300
Human Nod1 confers responsiveness to bacterial lipopolysaccharidesQ33923795
NODs: intracellular proteins involved in inflammation and apoptosisQ34199862
CARD15 mutations in Blau syndromeQ34517310
Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantationQ34561047
Toll-like receptors and T-helper-1/T-helper-2 responsesQ35160610
CCR2 is required for CD8-induced graft-versus-host disease.Q35848441
IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantationQ36001183
NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis inductionQ36259779
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.Q36330867
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantationQ40516766
NOD2/CARD15 polymorphisms in allogeneic stem-cell transplantation from unrelated donors: T depletion mattersQ44625050
Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Q44848328
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processingQ45251378
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's diseaseQ46504948
Induction of TNBS colitis in miceQ46630014
Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.Q51990275
Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs host disease.Q52511889
Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Q54620738
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndromeQ80809518
T cell activation by TLRs: a role for TLRs in the adaptive immune responseQ81039397
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontaminationQ82312167
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcell functionQ95674809
P304page(s)2101-2110
P577publication date2009-09-08
P1433published inJournal of Experimental MedicineQ3186912
P1476titleNOD2 regulates hematopoietic cell function during graft-versus-host disease
P478volume206

Reverse relations

cites work (P2860)
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