scholarly article | Q13442814 |
P50 | author | Steven G. E. Marsh | Q7615026 |
Neema P Mayor | Q60366069 | ||
Bronwen E Shaw | Q89210680 | ||
P2093 | author name string | J Alejandro Madrigal | |
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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection | Q24292675 | ||
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Crohn's disease-associated Nod2 mutants reduce IL10 transcription | Q47975511 | ||
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Interleukin 12 is associated with reduced relapse without increased incidence of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. | Q53644897 | ||
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Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement | Q28266531 | ||
Mapping of a susceptibility locus for Crohn's disease on chromosome 16 | Q28275042 | ||
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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses | Q28588300 | ||
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation | Q29615617 | ||
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry | Q29615618 | ||
Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15. | Q30351790 | ||
GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support | Q31991500 | ||
Crohn's disease and the NOD2 gene: a role for paneth cells | Q33187690 | ||
T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii | Q33577143 | ||
Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation | Q33839876 | ||
The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation | Q33898254 | ||
CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis | Q33906401 | ||
A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1. | Q34084039 | ||
NODs: intracellular proteins involved in inflammation and apoptosis | Q34199862 | ||
The NOD: a signaling module that regulates apoptosis and host defense against pathogens | Q34405567 | ||
Improving the outcome of unrelated donor stem cell transplantation by molecular matching | Q34494952 | ||
CARD15 mutations in Blau syndrome | Q34517310 | ||
Nods: a family of cytosolic proteins that regulate the host response to pathogens | Q34521834 | ||
Prevalence of CARD15/NOD2 mutations in Caucasian healthy people | Q34576207 | ||
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation | Q34582448 | ||
Mechanisms of action of antithymocyte globulin: T-cell depletion and beyond | Q34616147 | ||
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. | Q34870666 | ||
Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages | Q35128167 | ||
Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis | Q35596103 | ||
Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation? | Q35760212 | ||
LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation | Q36028584 | ||
T cell-mediated graft-versus-leukemia reactions after allogeneic stem cell transplantation | Q36123756 | ||
Chronic stimulation of Nod2 mediates tolerance to bacterial products | Q36288640 | ||
Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis. | Q36330867 | ||
Differential tumor surveillance by natural killer (NK) and NKT cells. | Q36375962 | ||
Hematopoietic stem-cell transplantation | Q36461248 | ||
NOD2/CARD15 disease associations other than Crohn's disease | Q36700677 | ||
Risk assessment in haematopoietic stem cell transplantation: histocompatibility | Q36797744 | ||
Risk assessment in haematopoietic stem cell transplantation: GvHD prevention and treatment | Q36797778 | ||
NLR proteins: integral members of innate immunity and mediators of inflammatory diseases | Q36944426 | ||
NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease | Q37172148 | ||
Polymorphisms of cytokine and innate immunity genes and GVHD. | Q37173452 | ||
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease | Q37216685 | ||
Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study | Q37268004 | ||
HLA-A disparities illustrate challenges for ranking the impact of HLA mismatches on bone marrow transplant outcomes in the United States | Q37354960 | ||
NOD2 regulates hematopoietic cell function during graft-versus-host disease | Q37377427 | ||
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition | Q37544531 | ||
Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors | Q37665086 | ||
Activation of human NK cells by the bacterial pathogen-associated molecular pattern muramyl dipeptide. | Q40005450 | ||
Use of natural killer cells as immunotherapy for leukaemia. | Q40047650 | ||
The NOD2-RICK complex signals from the plasma membrane. | Q40159855 | ||
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists | Q40382410 | ||
Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells | Q40382473 | ||
Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease | Q40411745 | ||
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation | Q40516766 | ||
Infevers: an evolving mutation database for auto-inflammatory syndromes | Q40528366 | ||
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan | Q40679561 | ||
Cytokine dysregulation as a mechanism of graft versus host disease | Q40780265 | ||
Graft-versus-leukemia reactions after bone marrow transplantation | Q41198977 | ||
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression | Q41917631 | ||
NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes | Q42526336 | ||
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease | Q43437819 | ||
Polymorphisms in innate immunity genes and risk of non-Hodgkin lymphoma | Q43897803 | ||
NOD2/CARD15 polymorphisms in allogeneic stem-cell transplantation from unrelated donors: T depletion matters | Q44625050 | ||
Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors. | Q44848328 | ||
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing | Q45251378 | ||
NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation | Q46108727 | ||
Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes | Q46240206 | ||
Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children | Q46297998 | ||
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release | Q46477488 | ||
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease | Q46504948 | ||
NOD2/CARD15 variants are not a risk factor for clinical outcome after nonmyeloablative allogeneic stem cell transplantation | Q46588677 | ||
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists | Q46602287 | ||
The effect of NOD2 activation on TLR2-mediated cytokine responses is dependent on activation dose and NOD2 genotype | Q46702416 | ||
Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation | Q46930661 | ||
Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome | Q47359749 | ||
Host dendritic cells alone are sufficient to initiate acute graft-versus-host disease | Q47371499 | ||
Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles. | Q47587797 | ||
NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype- phenotype analysis | Q47737388 | ||
CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease | Q47876286 | ||
NOD2/CARD15 polymorphisms impair innate immunity and increase susceptibility to gastric cancer in an Italian population. | Q47931892 | ||
Association between NOD2/CARD15 polymorphisms and coronary artery disease: a case-control study. | Q54373423 | ||
Elimination of graft-versus-host disease by in-vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (CAMPATH-1). | Q54469837 | ||
Common NOD2 mutations are absent in patients with Crohn's disease in India. | Q54501277 | ||
Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation. | Q54620738 | ||
The prevalence of genetic and serologic markers in an unselected European population-based cohort of IBD patients | Q57265428 | ||
Role ofNOD2 variants in spondylarthritis | Q57667873 | ||
High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism | Q57918712 | ||
Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation | Q59383486 | ||
Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G | Q61651674 | ||
Prevalence of the NOD2 3020insC mutation in aggregations of breast and lung cancer | Q61946726 | ||
Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation | Q62658651 | ||
Prevention of infection and graft-versus-host disease by suppression of intestinal microflora in children treated with allogeneic bone marrow transplantation | Q67271055 | ||
Hematopoietic stem cell transplantation: contrasting the outcome of transplantations from HLA-identical siblings, partially HLA-mismatched related donors, and HLA-matched unrelated donors | Q73256350 | ||
Is there a graft-versus-leukaemia effect in the absence of graft-versus-host disease in patients undergoing bone marrow transplantation for acute leukaemia? | Q73416370 | ||
Evidence that continued remission in patients treated for acute leukaemia is dependent upon autologous natural killer cells | Q74284510 | ||
The role of cytokines in acute graft-versus-host disease | Q77309371 | ||
Role of interleukin-12 in the development of acute graft-versus-host disease in bone marrow transplant patients | Q78094062 | ||
The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation | Q79768217 | ||
Clinical importance of HLA-DPB1 in haematopoietic cell transplantation | Q80184175 | ||
T-cell depletion prevents from bronchiolitis obliterans and bronchiolitis obliterans with organizing pneumonia after allogeneic hematopoietic stem cell transplantation with related donors | Q80292500 | ||
Impact of NOD2/CARD15 haplotypes on the outcome after kidney transplantation | Q80323241 | ||
Limits of HLA mismatching in unrelated hematopoietic cell transplantation | Q80337240 | ||
Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation | Q80408010 | ||
HLA Association with hematopoietic stem cell transplantation outcome: the number of mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 is strongly associated with overall survival | Q80640486 | ||
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome | Q80809518 | ||
No impact of NOD2/CARD15 on outcome after SCT | Q80813551 | ||
The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation | Q80860433 | ||
HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants | Q81370374 | ||
CARD15 mutations are rare in Swedish pediatric Crohn disease | Q81585225 | ||
No impact of NOD2/CARD15 on outcome after SCT: a reply | Q81770552 | ||
The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease | Q81880908 | ||
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination | Q82312167 | ||
Impact of high-resolution matching in allogeneic unrelated donor stem cell transplantation in Switzerland | Q82975022 | ||
Genetic variations of interleukin-23R (1143A>G) and BPI (A645G), but not of NOD2, are associated with acute graft-versus-host disease after allogeneic transplantation | Q84390923 | ||
Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors | Q84561203 | ||
NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation | Q84615437 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P304 | page(s) | 180391 | |
P577 | publication date | 2012-10-18 | |
P1433 | published in | Bone Marrow Research | Q26842195 |
P1476 | title | NOD2 Polymorphisms and Their Impact on Haematopoietic Stem Cell Transplant Outcome | |
P478 | volume | 2012 |
Q42376157 | Associations of interactions between NLRP3 SNPs and HLA mismatch with acute and extensive chronic graft-versus-host diseases |
Q86653462 | Can determination of gene polymorphism be of practical value in tailoring the treatment of HSCT patients? |
Q28080914 | Identification and utilization of donor and recipient genetic variants to predict survival after HCT: are we ready for primetime? |
Q38502469 | Non-HLA genomics: does it have a role in predicting haematopoietic stem cell transplantation outcome? |
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