Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation

scientific article

Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2009-09-243840
P932PMC publication ID2867270
P698PubMed publication ID20177049
P5875ResearchGate publication ID41532459

P50authorStephanie J. LeeQ55979666
Michael HaagensonQ89026448
Stephen SpellmanQ111077182
P2093author name stringTao Wang
Nicholas O Davidson
Ellen Li
Elizabeth Gorbe
Yume Nguyen
Abed Al-Lehibi
P2860cites workA frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's diseaseQ24681096
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
Twenty years of unrelated donor hematopoietic cell transplantation for adult recipients facilitated by the National Marrow Donor ProgramQ28291559
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tractQ28587612
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityQ29614872
The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantationQ33898254
Prevalence of CARD15/NOD2 mutations in Caucasian healthy peopleQ34576207
Recent understanding of IBD pathogenesis: implications for future therapiesQ36639759
Randomised trials of Graft versus Host Disease prophylaxis in haemopoietic stem cell transplantationQ37161359
The genetics and immunopathogenesis of inflammatory bowel diseaseQ37171800
GWA studies: rewriting the story of IBD.Q37393352
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantationQ40516766
Chronic graft-versus-host disease after allogeneic blood stem cell transplantationQ43727815
Relation of an interleukin-23 receptor gene polymorphism to graft-versus-host disease after hematopoietic-cell transplantationQ44241092
Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.Q44848328
Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in childrenQ46297998
NOD2 polymorphisms predict severe acute graft-versus-host and treatment-related mortality in T-cell-depleted haematopoietic stem cell transplantation.Q51819756
Influence of intestinal bacterial decontamination using metronidazole and ciprofloxacin or ciprofloxacin alone on the development of acute graft-versus-host disease after marrow transplantation in patients with hematologic malignancies: final resultQ53932647
Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.Q54620738
Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD.Q54628324
Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantationQ62658651
Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donorsQ70051817
The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantationQ79768217
No impact of NOD2/CARD15 on outcome after SCTQ80813551
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's diseaseQ81407622
Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontaminationQ82312167
Intestinal bacteria and inflammatory bowel diseaseQ83081820
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectinflammatory bowel diseasesQ917447
P304page(s)3625-3631
P577publication date2010-02-22
P1433published inBloodQ885070
P1476titleInsufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation
P478volume115

Reverse relations

cites work (P2860)
Q27021123Advances in predicting acute GVHD
Q54636018Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
Q28248522Association between NOD2 single nucleotide polymorphisms and Grade III-IV acute graft-versus-host disease: A meta-analysis
Q38134785Blau syndrome-associated uveitis and the NOD2 gene
Q28075204Danger Signals and Graft-versus-host Disease: Current Understanding and Future Perspectives
Q37875779Danger signals activating innate immunity in graft-versus-host disease
Q35224947Defining genetic risk for graft-versus-host disease and mortality following allogeneic hematopoietic stem cell transplantation.
Q86518787Donor TLR9 gene tagSNPs influence susceptibility to aGVHD and CMV reactivation in the allo-HSCT setting without polymorphisms in the TLR4 and NOD2 genes
Q37985519Genomic studies of GVHD-lessons learned thus far.
Q28080914Identification and utilization of donor and recipient genetic variants to predict survival after HCT: are we ready for primetime?
Q61955081NLR functions beyond pathogen recognition
Q38057238NOD2 Polymorphisms and Their Impact on Haematopoietic Stem Cell Transplant Outcome
Q34973978Recipient's genetic R702W NOD2 variant is associated with an increased risk of bacterial infections after orthotopic liver transplantation
Q38623211Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant
Q64257524The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease
Q37973866The IL-17 differentiation pathway and its role in transplant outcome
Q42252766The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation
Q41218452The role of bacteria and pattern recognition receptors in GVHD
Q26824436The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantation
Q38712496Translational opportunities for targeting the Th17 axis in acute graft-vs.-host disease

Search more.