Hox genes and region-specific sensorimotor circuit formation in the hindbrain and spinal cord

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Hox genes and region-specific sensorimotor circuit formation in the hindbrain and spinal cord is …
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scholarly articleQ13442814

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P356DOI10.1002/DVDY.24055
P698PubMed publication ID23996673
P5875ResearchGate publication ID256333151

P2093author name stringMichèle Studer
Joel C Glover
Maria Di Bonito
P2860cites workZebrafish Hoxb1a regulates multiple downstream genes including prickle1bQ47073778
Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.Q47808579
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genesQ48077000
Regional patterning of reticulospinal and vestibulospinal neurons in the hindbrain of mouse and rat embryosQ48164518
Responses of medial olivocochlear neurons. Specifying the central pathways of the medial olivocochlear reflexQ48172799
Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genesQ48182288
Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneuronsQ48208403
Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning.Q48273125
Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1.Q48365861
Origin and plasticity of the subdivisions of the inferior olivary complexQ48384260
Vestibular-mediated synaptic inputs and pathways to sympathetic preganglionic neurons in the neonatal mouseQ48389649
Development of the olivocerebellar projection in the rat: II. Matching of the developmental compartmentations of the cerebellum and inferior olive through the projection map.Q48430755
Hoxa2- and rhombomere-dependent development of the mouse facial somatosensory map.Q48449713
Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate mapsQ48573299
Math1 is essential for genesis of cerebellar granule neuronsQ48594976
Origin of cuneate projections to the anterior and posterior lobes of the rat cerebellumQ48672129
HoxB8 in noradrenergic specification and differentiation of the autonomic nervous systemQ48717217
Proprioceptor pathway development is dependent on Math1.Q48854506
Migratory pathways and selective aggregation of the lateral reticular neurons in the rat embryo: a horseradish peroxidase in vitro study, with special reference to migration patterns of the precerebellar nucleiQ49034020
Feedback control of the auditory periphery: anti-masking effects of middle ear muscles vs. olivocochlear efferents.Q50503187
Hox gene colinear expression in the avian medulla oblongata is correlated with pseudorhombomeric domains.Q51949409
Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.Q52030939
A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity.Q52034963
Motor neuron columnar fate imposed by sequential phases of Hox-c activity.Q52098449
Development of order in the rat trigeminal system.Q52282803
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbxQ52537224
Segmental patterning of rat and chicken sympathetic preganglionic neurons: correlation between soma position and axon projection pathway.Q52884591
Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina.Q53753517
Segmentation in the vertebrate nervous systemQ59051768
The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nucleiQ59205638
Development of the precerebellar nuclei in the rat: I. The precerebellar neuroepithelium of the rhombencephalonQ69473779
Development of the precerebellar nuclei in the rat: II. The intramural olivary migratory stream and the neurogenetic organization of the inferior oliveQ69473782
Development of the precerebellar nuclei in the rat: III. The posterior precerebellar extramural migratory stream and the lateral reticular and external cuneate nucleiQ69473783
Morphological fate of rhombomeres in quail/chick chimeras: a segmental analysis of hindbrain nucleiQ71795898
Rostrocaudal nuclear relationships in the avian medulla oblongata: a fate map with quail chick chimerasQ73135643
The derivatives of the Wnt3a lineage in the central nervous systemQ80802362
Mapping cell fate and function using recombinase-based intersectional strategiesQ84713043
Rautenlippe Redux -- toward a unified view of the precerebellar rhombic lipQ24634639
Genetic dissection of the function of hindbrain axonal commissuresQ27324810
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptorsQ28118661
Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrainQ28143128
Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complexQ28203651
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) geneQ28236533
Compartments and their boundaries in vertebrate brain developmentQ28256915
Vestibular system: the many facets of a multimodal senseQ28272563
Segmentation in the chick embryo hindbrain is defined by cell lineage restrictionsQ28280395
Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signalingQ28472970
Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellumQ28508334
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axonsQ28509522
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellumQ28510132
Math1: an essential gene for the generation of inner ear hair cellsQ28513764
Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neuronsQ28587120
Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesisQ28588303
The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axonsQ28593361
Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1Q28593607
Chromatin signatures of pluripotent cell linesQ29614675
Neuronal specification in the spinal cord: inductive signals and transcriptional codesQ29616039
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous systemQ29616040
Hox genes in vertebrate developmentQ29618109
Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem.Q30458263
HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- miceQ30459147
Math5 expression and function in the central auditory systemQ30481442
Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nucleiQ30486773
Cochlear amplification, outer hair cells and prestinQ30487712
Selective removal of lateral olivocochlear efferents increases vulnerability to acute acoustic injuryQ30497090
Medial olivocochlear reflex interneurons are located in the posteroventral cochlear nucleus: a kainic acid lesion study in guinea pigsQ30499671
Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins.Q31814871
Cerebellar nuclei and the nucleocortical projections in the rat: retrograde tracing coupled to GABA and glutamate immunohistochemistryQ33190035
Central auditory pathways mediating the rat middle ear muscle reflexesQ33237135
Segment-specific pattern of sympathetic preganglionic projections in the chicken embryo spinal cord is altered by retinoidsQ33560599
Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.Q33564062
Math1 is essential for the development of hindbrain neurons critical for perinatal breathingQ33637710
Slit proteins: key regulators of axon guidance, axonal branching, and cell migrationQ33840691
Extension of long leading processes and neuronal migration in the mammalian brain directed by the chemoattractant netrin-1.Q33883487
Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoterQ33926057
The rhombic lip and early cerebellar developmentQ33933604
Neuroepithelial 'compartments' and the specification of vestibular projectionsQ34003249
Correlated patterns of neuron differentiation and Hox gene expression in the hindbrain: a comparative analysisQ34094631
The relationship between hodological and cytoarchitectonic organization in the vestibular complex of the 11-day chicken embryoQ34172190
Hoxb1 controls anteroposterior identity of vestibular projection neuronsQ34224992
The development of vestibulo-ocular circuitry in the chicken embryoQ34287820
Patterning the vertebrate neuraxisQ34405115
Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1.Q34411125
Embryonic origins of the mouse superior olivary complexQ34443441
Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.Q34464666
Long-term effects of sectioning the olivocochlear bundle in neonatal cats.Q34466416
The relationship between rhombomeres and vestibular neuron populations as assessed in quail-chicken chimerasQ34473759
The sensory and motor roles of auditory hair cellsQ34478832
Segmental patterns of neuronal development in the chick hindbrainQ34497251
Hox cofactors in vertebrate developmentQ34499501
A distinct Hox code for the branchial region of the vertebrate headQ34545764
Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neuronsQ34566349
Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrainQ34572061
Comparative aspects of the hodological organization of the vestibular nuclear complex and related neuron populationsQ34581615
Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain developmentQ34664018
Fate-mapping the mammalian hindbrain: segmental origins of vestibular projection neurons assessed using rhombomere-specific Hoxa2 enhancer elements in the mouse embryoQ34679925
Origin of climbing fiber neurons and their developmental dependence on Ptf1aQ34700132
Hox genes and spinal cord developmentQ34764976
Development of the inner ear efferent system across vertebrate speciesQ34968753
Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fatesQ35202057
Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expressionQ35691115
Somite polarity and segmental patterning of the peripheral nervous systemQ35857135
Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors.Q35964537
GABAergic neuron specification in the spinal cord, the cerebellum, and the cochlear nucleusQ36090789
Patterning in the vertebrate limbQ36552546
Olivocochlear efferents: anatomy, physiology, function, and the measurement of efferent effects in humansQ36645702
Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neuronsQ36775375
Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architectureQ36942794
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.Q37288224
Hox genes and segmentation of the vertebrate hindbrainQ37570818
Hox genes in neural patterning and circuit formation in the mouse hindbrainQ37570822
Mapping the face in the somatosensory brainstemQ37697491
Patterning of pre-thalamic somatosensory pathwaysQ38011197
Distinct transcriptomes define rostral and caudal serotonin neuronsQ38507715
Segmental patterns of vestibular-mediated synaptic inputs to axial and limb motoneurons in the neonatal mouse assessed by optical recordingQ39825672
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cellsQ39840959
The specificity of homeotic gene functionQ40375266
Hox homeobox genes and regionalisation of the nervous system.Q40618310
Origin of the precerebellar system.Q40741359
Development of second-order vestibular projections in the chicken embryoQ41023858
Hox transcription factors influence motoneuron identity through the integrated actions of both homeodomain and non-homeodomain regionsQ42026912
Sustained Hox5 gene activity is required for respiratory motor neuron developmentQ42048499
Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.Q42142594
Global control of motor neuron topography mediated by the repressive actions of a single hox gene.Q42409696
Role of Shh in the development of molecularly characterized tegmental nuclei in mouse rhombomere 1.Q42435713
The development of vestibulocochlear efferents and cochlear afferents in miceQ42442978
Development of the nuclei and cell migration in the medulla oblongata. Application of the quail-chick chimera systemQ42471631
Polycomb repressive complex 1 activities determine the columnar organization of motor neuronsQ42475844
Development of the precerebellar nuclei in the rat: IV. The anterior precerebellar extramural migratory stream and the nucleus reticularis tegmenti pontis and the basal pontine grayQ42524531
Efferent protection from acoustic injury is mediated via alpha9 nicotinic acetylcholine receptors on outer hair cells.Q44251943
Regional specificity of developing reticulospinal, vestibulospinal, and vestibulo-ocular projections in the chicken embryoQ44671457
Embryonic origins of auditory brain-stem nuclei in the chick hindbrainQ44874606
Conditioning-related protection from acoustic injury: effects of chronic deefferentation and sham surgeryQ46266370
Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitorsQ46734167
Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal hornQ46807717
P433issue12
P304page(s)1348-1368
P577publication date2013-11-08
P1433published inDevelopmental DynamicsQ59752
P1476titleHox genes and region-specific sensorimotor circuit formation in the hindbrain and spinal cord
P478volume242

Reverse relations

cites work (P2860)
Q30357260Cellular and Molecular Underpinnings of Neuronal Assembly in the Central Auditory System during Mouse Development.
Q47104912Conditional Loss of Hoxa5 Function Early after Birth Impacts on Expression of Genes with Synaptic Function
Q39718025HOX gene complement and expression in the planarian Schmidtea mediterranea
Q48444762HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons
Q47243963Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
Q36419065Loss of Projections, Functional Compensation, and Residual Deficits in the Mammalian Vestibulospinal System of Hoxb1-Deficient Mice
Q47123751Nuclear derivatives and axonal projections originating from rhombomere 4 in the mouse hindbrain.
Q30397856Organization of pontine reticulospinal inputs to motoneurons controlling axial and limb muscles in the neonatal mouse
Q90175827Regionally Distinct Astrocytes Display Unique Transcription Factor Profiles in the Adult Brain
Q49049486Revisiting the segmental organization of the human spinal cord.
Q34171320Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development.
Q41665665Systematic expression analysis of Hox genes at adulthood reveals novel patterns in the central nervous system
Q38337997The emerging framework of mammalian auditory hindbrain development
Q33630153Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis.
Q49971231Wilhelm His' lasting insights into hindbrain and cranial ganglia development and evolution.

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