Differential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies.

scientific article published on January 2014

Differential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/10408398.2011.565456
P698PubMed publication ID24188302
P5875ResearchGate publication ID258280325

P50authorCinta BladéQ56826370
Josepa SalvadóQ59689486
Francesc PuiggrósQ117224042
Lluís ArolaQ39724540
P2860cites workAntiradical capacity and induction of apoptosis on HeLa cells by a Phaseolus vulgaris extractQ46839882
Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.Q47296339
Grape seed extract given three hours after injury suppresses lipid peroxidation and reduces hypoxic-ischemic brain injury in neonatal ratsQ48266543
Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis.Q53359482
Mitochondrial activation of apoptosisQ55920332
SEK1/MKK4-Mediated SAPK/JNK Signaling Participates in Embryonic Hepatoblast Proliferation via a Pathway Different from NF-κB-Induced Anti-ApoptosisQ57185172
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12Q24300914
Induction of apoptosis in human leukemia cells by grape seed extract occurs via activation of c-Jun NH2-terminal kinaseQ24654047
H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.Q40657727
Procyanidins protect Fao cells against hydrogen peroxide-induced oxidative stressQ40707482
Dietary grape seed proanthocyanidins inhibit UVB-induced cyclooxygenase-2 expression and other inflammatory mediators in UVB-exposed skin and skin tumors of SKH-1 hairless miceQ43167719
Delphinidin attenuates stress injury induced by oxidized low-density lipoprotein in human umbilical vein endothelial cellsQ43264227
The mitochondrion: is it central to apoptosis?Q43593108
Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cellsQ43680829
Protective effects of antioxidants against smokeless tobacco-induced oxidative stress and modulation of Bcl-2 and p53 genes in human oral keratinocytesQ43791202
Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor modelQ43835455
Epicatechin, procyanidins, and phenolic microbial metabolites after cocoa intake in humans and ratsQ43898256
Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in ratsQ44043006
Composition of phenolic compounds in a Portuguese pear (Pyrus communis L. var. S. Bartolomeu) and changes after sun-drying.Q44076497
Studies in polyphenol chemistry and bioactivity. 4.(1) Synthesis of trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having all-4beta,8-interflavan connectivity and their inhibition of cancer cell growth throuQ44331175
Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosisQ44347010
Measurement of plasma procyanidin B-2 and procyanidin B-3 levels after oral administration in ratQ44425955
Protective effect of S-allyl-l-cysteine, a garlic compound, on amyloid β-protein-induced cell death in nerve growth factor-differentiated PC12 cellsQ44426291
Grape seed proanthocyanidin extract attenuates oxidant injury in cardiomyocytesQ44437523
Grape seed proanthocyanidins induce pro-oxidant toxicity in cardiomyocytesQ44735948
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitroQ44782704
Epidermal interleukin-1 is increased in cutaneous T-cell lymphomaQ44922353
Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell deathQ45230783
Proanthocyanidin prevents methotrexate-induced intestinal damage and oxidative stressQ46071245
Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat dietQ46500697
Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deathsQ46730439
Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK.Q46755946
Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's diseaseQ46812957
Both ERK and JNK are required for enhancement of MD-2 gene expression during differentiation of HL-60 cellsQ46817882
A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacologyQ28216875
Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathwayQ28222550
Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8Q28238607
Principles of tumor suppressionQ28240740
Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cellsQ28270316
Multiple levels of cyclin specificity in cell-cycle controlQ28284728
Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juicesQ28293845
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.Q28567147
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosisQ28588618
Cocoa and chocolate flavonoids: Implications for cardiovascular healthQ29011719
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesQ29614338
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathwayQ29616436
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosisQ29616513
Cancer chemoprevention with dietary phytochemicalsQ29617743
Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extractQ33394484
Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ miceQ33588312
Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c releaseQ33962301
Molecular basis of anthracycline-induced cardiotoxicity and its preventionQ34043229
Potential health impacts of excessive flavonoid intakeQ34062734
The cellular and molecular basis of health benefits of grape seed proanthocyanidin extractQ34085503
Free radicals and brain damage in the newbornQ34199199
Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cellsQ34400210
The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats.Q34444736
Green tea and its polyphenolic catechins: medicinal uses in cancer and noncancer applicationsQ34489512
Protecting against anthracycline-induced myocardial damage: a review of the most promising strategiesQ34563378
Low molecular proanthocyanidin dietary biofactor Oligonol: Its modulation of oxidative stress, bioefficacy, neuroprotection, food application and chemoprevention potentialsQ34570455
Chemoprevention with phytochemicals targeting inducible nitric oxide synthaseQ34606521
Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanismsQ34680097
Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathwaysQ34725013
Dietary phenolics: chemistry, bioavailability and effects on healthQ34994426
The role of mitogen-activated protein kinase pathways in Alzheimer's diseaseQ35059550
Mitochondria in cell death: novel targets for neuroprotection and cardioprotectionQ35134634
Targeting the PI3K-Akt pathway in human cancer: rationale and promiseQ35571372
Neuroprotection by bioactive components in medicinal and food plant extractsQ35596026
Coupling endoplasmic reticulum stress to the cell death programQ35649891
Mitogen-activated protein kinases in apoptosis regulationQ35743118
Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseasesQ35820578
Mitogen-activated protein kinases and the evolution of Alzheimer's: a revolutionary neurogenetic axis for therapeutic intervention?Q35863566
STRESS signaling pathways that modulate cardiac myocyte apoptosisQ35995681
Phosphoinositide 3-kinases as drug targets in cancerQ36166811
Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration.Q36380401
The role of cell cycle regulatory proteins in the pathogenesis of melanoma.Q36568961
Procyanidin effects on adipocyte-related pathologies.Q36586055
Tumor-targeted induction of oxystress for cancer therapyQ36900213
Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cellsQ37003146
Flavan-3-ols: nature, occurrence and biological activityQ37032487
CDK inhibitors: cell cycle regulators and beyondQ37081857
Vascular action of polyphenols.Q37339907
Flavonoids with gastroprotective activity.Q37420344
Tannins: current knowledge of food sources, intake, bioavailability and biological effects.Q37479432
Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms.Q37644349
Healthy properties of proanthocyanidins.Q37709934
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathwaysQ39680978
Apple procyanidins activate apoptotic signaling pathway in human colon adenocarcinoma cells by a lipid-raft independent mechanismQ39814830
Procyanidin induces apoptosis and necrosis of prostate cancer cell line PC-3 in a mitochondrion-dependent mannerQ39922951
Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerizationQ39953483
Catechin and proanthocyanidin B4 from grape seeds prevent doxorubicin-induced toxicity in cardiomyocytesQ39963667
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targetsQ39995376
Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell lineQ40070483
Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3.Q40083071
The importance of polymerization and galloylation for the antiproliferative properties of procyanidin-rich natural extractsQ40083604
Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potentialQ40145242
Grape seed polyphenols protect cardiac cells from apoptosis via induction of endogenous antioxidant enzymesQ40171962
Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levelsQ40232287
Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cellsQ40295284
Chemopreventive activity of polyphenolics from black Jamapa bean (Phaseolus vulgaris L.) on HeLa and HaCaT cells.Q40305269
Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems.Q40395941
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosisQ40509474
P433issue3
P921main subjectapoptotic processQ14599311
P304page(s)277-291
P577publication date2014-01-01
P1433published inCritical Reviews in Food Science and NutritionQ15716669
P1476titleDifferential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies
P478volume54

Reverse relations

cites work (P2860)
Q55069884Proanthocyanidins against Oxidative Stress: From Molecular Mechanisms to Clinical Applications.
Q64267872Protect against -Induced Oxidative Damage in Bovine Endometrial Cells
Q90636118Surface Functionalization with Proanthocyanidins Provides an Anti-Oxidant Defense Mechanism That Improves the Long-Term Stability and Osteogenesis of Titanium Implants

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