Amyotrophic lateral sclerosis: applications of stem cells - an update.

scientific article published on 27 October 2010

Amyotrophic lateral sclerosis: applications of stem cells - an update. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/SCCAA.S8662
P8608Fatcat IDrelease_6e6ivvjpqzbtfloucv2rln7dte
P932PMC publication ID3781739
P698PubMed publication ID24198520

P50authorLidia CovaQ57008113
P2093author name stringVincenzo Silani
P2860cites workDose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS miceQ44472268
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Human neural precursor cells continue to proliferate and exhibit low cell death after transplantation to the injured rat spinal cordQ48655205
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GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.Q33292690
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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).Q34010341
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.Q34044401
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Nuclear factor TDP-43 can affect selected microRNA levelsQ34112413
The skin in amyotrophic lateral sclerosisQ34314425
Autologous mesenchymal stem cells: clinical applications in amyotrophic lateral sclerosisQ34568739
Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS modelQ34596280
Transplanted mouse embryonic stem-cell-derived motoneurons form functional motor units and reduce muscle atrophy.Q50612517
Reestablishment of damaged adult motor pathways by grafted embryonic cortical neurons.Q50666206
Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues.Q50790361
Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans.Q51653840
High frequency of TARDBP gene mutations in Italian patients with amyotrophic lateral sclerosis.Q51815155
Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis.Q51868850
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.Q51986995
Role of matrix metalloproteinase-9 in a mouse model for amyotrophic lateral sclerosisQ57244961
Motoneuron Transplantation Rescues the Phenotype of SMARD1 (Spinal Muscular Atrophy with Respiratory Distress Type 1)Q61943890
Skin abnormalities and autonomic involvement in the early stage of amyotrophic lateral sclerosisQ72469137
Matrix metalloproteinases MMP-2, MMP-7 and MMP-9 in denervated human muscleQ73053509
Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosisQ73234498
Collagen abnormalities in the spinal cord from patients with amyotrophic lateral sclerosisQ77669214
Matrix metalloproteinases--a conceptional alternative for disease-modifying strategies in ALS/MND?Q79814466
Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosisQ79960014
Dyslipidemia is a protective factor in amyotrophic lateral sclerosisQ80503053
Stem cell treatment in Amyotrophic Lateral SclerosisQ80507987
Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS)Q80856779
Temporal response of neural progenitor cells to disease onset and progression in amyotrophic lateral sclerosis-like transgenic miceQ81037241
Stem-cell therapy in amyotrophic lateral sclerosisQ81065129
The pro and the active form of matrix metalloproteinase-9 is increased in serum of patients with amyotrophic lateral sclerosisQ81277193
Metalloproteinase alterations in the bone marrow of ALS patientsQ82595342
The matrix metalloproteinases inhibitor Ro 28-2653 [correction of Ro 26-2853] extends survival in transgenic ALS miceQ82725703
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Human stem cells and drug screening: opportunities and challengesQ83910679
Stem cell renegades or pioneers?Q84161552
A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosisQ84520182
Numerous FUS-positive inclusions in an elderly woman with motor neuron diseaseQ84608229
Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosisQ84612193
Serum markers of type I collagen synthesis and degradation in amyotrophic lateral sclerosisQ95811029
Neurodegenerative disease-specific induced pluripotent stem cell researchQ37737385
The adult neural stem and progenitor cell niche is altered in amyotrophic lateral sclerosis mouse brainQ38312756
TARDBP mutations in motoneuron disease with frontotemporal lobar degenerationQ38382616
Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up.Q39311874
Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice.Q39759649
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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cellsQ39910905
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutationQ39910909
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Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosisQ40035096
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Short-term outcome of olfactory ensheathing cells transplantation for treatment of amyotrophic lateral sclerosisQ40437067
Functional properties of motoneurons derived from mouse embryonic stem cells.Q40517622
Altered expression of the glutamate transporter EAAT2b in neurological diseaseQ40572506
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Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron diseaseQ42188656
Intrathecal application of neuroectodermally converted stem cells into a mouse model of ALS: limited intraparenchymal migration and survival narrows therapeutic effectsQ42512822
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in miceQ42722532
Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosisQ42962080
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake.Q43014458
Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein.Q43028561
Human adipose-derived stem cells enhance the glutamate uptake function of GLT1 in SOD1(G93A)-bearing astrocytesQ43163559
Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson's disease.Q43234179
Fetal olfactory ensheathing cells transplantation in amyotrophic lateral sclerosis patients: a controlled pilot studyQ43513937
Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS modelQ43628011
Cell therapy and stem cells in animal models of motor neuron disorders.Q34693599
Variation in the safety of induced pluripotent stem cell linesQ34991636
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosisQ35094527
Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.Q35633071
Stem-cell therapy for amyotrophic lateral sclerosis.Q35832769
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.Q35928006
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosisQ35987553
Overlap between neurodegenerative disordersQ36117422
Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cellsQ36158013
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Molecular biology of amyotrophic lateral sclerosis: insights from geneticsQ36573336
The RNA-binding protein HuD: a regulator of neuronal differentiation, maintenance and plasticityQ36574657
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.Q36677109
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS.Q36899833
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease.Q36991962
Combining growth factor and stem cell therapy for amyotrophic lateral sclerosisQ37105854
Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeuticsQ37134134
The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis.Q37254394
Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small moleculesQ37254921
Research in motion: the enigma of Parkinson's disease pathology spreadQ37260288
Is it too soon for mesenchymal stem cell trials in people with ALS?Q37279972
Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice.Q37290026
Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: differentiation and structural integration into the segmental motor circuitryQ37307371
Cervical spinal cord therapeutics delivery: preclinical safety validation of a stabilized microinjection platformQ37393215
Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohortQ37393988
Rethinking ALS: the FUS about TDP-43.Q37419912
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.Q37444336
Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic modelsQ37455509
MicroRNA and stem cell regulation.Q37500194
Stem cells in amyotrophic lateral sclerosis: state of the art.Q37575591
The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS).Q37617743
Neurogenesis of corticospinal motor neurons extending spinal projections in adult miceQ37621803
MicroRNA control of signal transductionQ37706077
Molecular pathways of frontotemporal lobar degenerationQ37736479
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P921main subjectamyotrophic lateral sclerosisQ206901
P304page(s)145-156
P577publication date2010-10-27
P1433published inStem Cells and Cloning: advances and applicationsQ15817523
P1476titleAmyotrophic lateral sclerosis: applications of stem cells - an update
P478volume3

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cites work (P2860)
Q36861763Differentiation of CD133+ stem cells from amyotrophic lateral sclerosis patients into preneuron cells
Q34182540Longitudinal tracking of human fetal cells labeled with super paramagnetic iron oxide nanoparticles in the brain of mice with motor neuron disease
Q45845978NMR Metabolomics for Stem Cell type discrimination.

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