Exercise: is it a neuroprotective and if so, how does it work?

scientific article published on January 2014

Exercise: is it a neuroprotective and if so, how does it work? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1353-8020(13)70030-0
P698PubMed publication ID24262162
P5875ResearchGate publication ID258827563

P50authorRichard J SmeyneQ42566386
P2093author name stringMichael J Zigmond
P2860cites workEffects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: Time course of protection and neurorestorationQ39634067
A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigraQ40247260
Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man.Q41334106
Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivoQ41428400
Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal gangliaQ42464444
Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine.Q43638930
Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors.Q44681088
Physical activity and the risk of Parkinson diseaseQ45296127
Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotectionQ46075149
Enriched environment induces cellular plasticity in the adult substantia nigra and improves motor behavior function in the 6-OHDA rat model of Parkinson's diseaseQ46855586
Repetitive vibrissae-elicited forelimb placing before and immediately after unilateral 6-hydroxydopamine improves outcome in a model of Parkinson's diseaseQ48234396
Enriched environment improves motor function in intact and unilateral dopamine-depleted rats.Q48552407
Neurotrophic factors in Alzheimer's and Parkinson's disease brainQ64768197
The effectiveness of exercise interventions for people with Parkinson's disease: A systematic review and meta-analysisQ22252884
Neural consequences of environmental enrichmentQ22337282
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson diseaseQ28187904
Effect of sublethal 6-hydroxydopamine on the response to subsequent oxidative stress in dopaminergic cells: evidence for preconditioningQ33256562
Exercise protects against MPTP-induced neurotoxicity in mice.Q33907587
Environmental enrichment in adulthood eliminates neuronal death in experimental ParkinsonismQ33985962
Physical activities and future risk of Parkinson diseaseQ34054934
Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundleQ34328723
Presymptomatic compensation in Parkinson's disease is not dopamine-mediatedQ35104797
Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidineQ36019710
Molecular pathophysiology of Parkinson's diseaseQ36196507
Enriched environments, experience-dependent plasticity and disorders of the nervous system.Q36573332
Compensations after lesions of central dopaminergic neurons: some clinical and basic implicationsQ36586049
Exercise builds brain health: key roles of growth factor cascades and inflammationQ36926512
Neurotoxin-based models of Parkinson's diseaseQ37959729
Neural and immune mechanisms in the pathogenesis of Parkinson's disease.Q38078895
P407language of work or nameEnglishQ1860
P304page(s)S123-7
P577publication date2014-01-01
P1433published inParkinsonism and Related DisordersQ15762600
P1476titleExercise: is it a neuroprotective and if so, how does it work?
P478volume20 Suppl 1

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cites work (P2860)
Q92753479A Stage-Based Approach to Therapy in Parkinson's Disease
Q35835050A comparison of dance interventions in people with Parkinson disease and older adults
Q60616835Ambulatory Activity in People with Early Parkinson's Disease
Q36925905Current Pharmaceutical Treatments and Alternative Therapies of Parkinson's Disease
Q39418858DNP, mitochondrial uncoupling, and neuroprotection: A little dab'll do ya.
Q47681828Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease: A Phase 2 Randomized Clinical Trial
Q96135942Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine -induced Parkinson in male NMRI mice
Q41884810Evaluating rehabilitation interventions in Parkinson's disease with functional MRI: a promising neuroprotective strategy
Q47260664Evaluation of exercise-induced modulation of glial activation and dopaminergic damage in a rat model of Parkinson's disease using [11C]PBR28 and [18F]FDOPA PET.
Q30371129Evidence for early and progressive ultrasonic vocalization and oromotor deficits in a PINK1 gene knockout rat model of Parkinson's disease
Q55409191Exercise Ameliorates Motor Deficits and Improves Dopaminergic Functions in the Rat Hemi-Parkinson's Model.
Q30383666Exercise Effects on Early Vocal Ultrasonic Communication Dysfunction in a PINK1 Knockout Model of Parkinson's Disease
Q89414984Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal PGC-1α/FNDC5/BDNF Pathway
Q37051146Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats
Q55278902Exercise-induced increase in brain-derived neurotrophic factor in human Parkinson's disease: a systematic review and meta-analysis.
Q35915111HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta
Q55175005How the Body Talks to the Brain; Peripheral Mediators of Physical Activity-Induced Proliferation in the Adult Hippocampus.
Q92308934Long-Term Voluntary Physical Exercise Exerts Neuroprotective Effects and Motor Disturbance Alleviation in a Rat Model of Parkinson's Disease
Q47805030Long-term effects of exercise and physical therapy in people with Parkinson disease
Q47975487Magnesium boosts the memory restorative effect of environmental enrichment in Alzheimer's disease mice.
Q37480232Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges
Q64761569N-Acetyl Cysteine Is Associated With Dopaminergic Improvement in Parkinson's Disease
Q30000089N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data
Q64081721Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson's Disease
Q30377906Nonpharmacological treatments for patients with Parkinson's disease.
Q39050215Physical therapy and occupational therapy in Parkinson's disease
Q42053472Restoration of MPTP-induced deficits by exercise and Milmed(®) co-treatment.
Q45178969Running wheel exercise before a binge regimen of methamphetamine does not protect against striatal dopaminergic damage
Q47260625Running wheel exercise reduces α-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease.
Q41449163Social and environmental enrichment has different effects on ethanol and sucrose consumption in mice
Q38805550Subthalamic nucleus deep brain stimulation is neuroprotective in the A53T α-synuclein Parkinson's disease rat model.
Q35555805The cyclical lower extremity exercise for Parkinson's trial (CYCLE): methodology for a randomized controlled trial
Q30244421The epidemiology of Parkinson's disease: risk factors and prevention
Q92713972The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson's disease
Q26745661The recommendations of Chinese Parkinson's disease and movement disorder society consensus on therapeutic management of Parkinson's disease
Q52623796The role of suboptimal mitochondrial function in vulnerability to post-traumatic stress disorder.
Q53667436The roles of motor activity and environmental enrichment in intellectual disability.
Q38925121Therapies for Parkinson's diseases: alternatives to current pharmacological interventions.
Q50117645Voluntary Physical Exercise Improves Subsequent Motor and Cognitive Impairments in a Rat Model of Parkinson's Disease
Q42314849What Goes Around Can Come Around: An Unexpected Deleterious Effect of Using Mouse Running Wheels for Environmental Enrichment

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