HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta

scientific article published on 19 March 2015

HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta is …
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scholarly articleQ13442814

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P356DOI10.1016/J.NEUROSCIENCE.2015.03.015
P8608Fatcat IDrelease_eitu43h4vjcptee7q7z5xthtdm
P932PMC publication ID4524512
P698PubMed publication ID25796140
P5875ResearchGate publication ID273790423

P2093author name stringY Jiao
R J Smeyne
I Dragatsis
M Smeyne
P Sladen
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The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytesQ80738743
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathwayQ85047994
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activationQ24294741
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A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor.Q38315547
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The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouseQ40917798
Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia.Q41671014
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The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.Q48421828
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Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.Q52187450
Substrains of inbred mice differ in their physical activity as a behavior.Q55003838
Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxiaQ73128142
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P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
substantia nigraQ753278
dopaminergic neuronQ66591220
P1104number of pages16
P304page(s)23-38
P577publication date2015-03-19
P1433published inNeuroscienceQ15708571
P1476titleHIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta
P478volume295