scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.NEUROSCIENCE.2015.03.015 |
P8608 | Fatcat ID | release_eitu43h4vjcptee7q7z5xthtdm |
P932 | PMC publication ID | 4524512 |
P698 | PubMed publication ID | 25796140 |
P5875 | ResearchGate publication ID | 273790423 |
P2093 | author name string | Y Jiao | |
R J Smeyne | |||
I Dragatsis | |||
M Smeyne | |||
P Sladen | |||
P2860 | cites work | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 |
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation | Q24291783 | ||
A conserved family of prolyl-4-hydroxylases that modify HIF | Q24291794 | ||
The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes | Q80738743 | ||
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway | Q85047994 | ||
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation | Q24294741 | ||
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells | Q24314526 | ||
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia | Q24315006 | ||
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 | Q24320257 | ||
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development | Q24595910 | ||
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
HIF-1: mediator of physiological and pathophysiological responses to hypoxia | Q28140835 | ||
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha | Q28259513 | ||
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis | Q28279053 | ||
Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms | Q28361631 | ||
Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling | Q28394742 | ||
Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factors | Q28578496 | ||
Hypoxia inducible factor (HIF)-2 alpha is required for the development of the catecholaminergic phenotype of sympathoadrenal cells | Q28579611 | ||
Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1 | Q28581618 | ||
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling | Q28592049 | ||
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice | Q28594703 | ||
Purification and characterization of hypoxia-inducible factor 1 | Q28678375 | ||
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription | Q29614203 | ||
Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease | Q33201042 | ||
Exercise protects against MPTP-induced neurotoxicity in mice. | Q33907587 | ||
Exercise: a behavioral intervention to enhance brain health and plasticity | Q33959877 | ||
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. | Q34351068 | ||
Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice. | Q34389461 | ||
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension | Q34582873 | ||
Exercise, oxidative stress and hormesis | Q34687654 | ||
Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegeneration | Q34812895 | ||
Integration of CNS survival and differentiation by HIF2α. | Q35302094 | ||
GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism | Q35616756 | ||
Anti-inflammatory effects of physical activity in relationship to improved cognitive status in humans and mouse models of Alzheimer's disease | Q35652616 | ||
Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice | Q35839143 | ||
Structural and functional adaptation to hypoxia in the rat brain. | Q35857993 | ||
The MPTP model of Parkinson's disease | Q36080019 | ||
Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity | Q36081569 | ||
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. | Q36081630 | ||
MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview | Q36129331 | ||
Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta | Q36156158 | ||
Environment, physical activity, and neurogenesis: implications for prevention and treatment of Alzhemier's disease | Q36393764 | ||
The cellular basis for diverse responses to oxygen | Q36692777 | ||
Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis | Q36835517 | ||
Glutathione metabolism and Parkinson's disease | Q37078480 | ||
A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse | Q37248811 | ||
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning | Q37781873 | ||
Exercise: is it a neuroprotective and if so, how does it work? | Q38164870 | ||
The effects of exercise on cognition in Parkinson's disease: a systematic review. | Q38190119 | ||
A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor. | Q38315547 | ||
Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1. | Q38340206 | ||
Exercise exerts neuroprotective effects on Parkinson's disease model of rats | Q39777204 | ||
The redox state of glutathione regulates the hypoxic induction of HIF-1. | Q39859743 | ||
The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse | Q40917798 | ||
Detection of hypoxic cells with the 2-nitroimidazole, EF5, correlates with early redox changes in rat brain after perinatal hypoxia-ischemia. | Q41671014 | ||
Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus. | Q42471915 | ||
Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. | Q42492807 | ||
Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse. | Q42713050 | ||
Adenosine A(2)A receptor but not HIF-1 mediates Tyrosine hydroxylase induction in hypoxic PC12 cells. | Q43167606 | ||
Role of nitric oxide in the regulation of HIF-1alpha expression during hypoxia | Q44021409 | ||
HIF-1alpha in endurance training: suppression of oxidative metabolism | Q46102076 | ||
Glia cell number modulates sensitivity to MPTP in mice | Q46514011 | ||
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation | Q46626427 | ||
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia | Q48072985 | ||
Preischemic exercise reduces brain damage by ameliorating metabolic disorder in ischemia/reperfusion injury | Q48098313 | ||
Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia | Q48144169 | ||
Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2. | Q48341361 | ||
The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. | Q48421828 | ||
Exercise pre-conditioning reduces brain inflammation in stroke via tumor necrosis factor-alpha, extracellular signal-regulated kinase 1/2 and matrix metalloproteinase-9 activity | Q48485210 | ||
Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity | Q48810066 | ||
Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. | Q52119910 | ||
Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. | Q52187450 | ||
Substrains of inbred mice differ in their physical activity as a behavior. | Q55003838 | ||
Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia | Q73128142 | ||
CaMKIIalpha-Cre transgene expression and recombination patterns in the mouse brain | Q73473631 | ||
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia | Q74232986 | ||
Increased astrocyte proliferation in rats after running exercise | Q80384445 | ||
Genetic influence on daily wheel running activity level | Q80597460 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | dopamine | Q170304 |
substantia nigra | Q753278 | ||
dopaminergic neuron | Q66591220 | ||
P1104 | number of pages | 16 | |
P304 | page(s) | 23-38 | |
P577 | publication date | 2015-03-19 | |
P1433 | published in | Neuroscience | Q15708571 |
P1476 | title | HIF1α is necessary for exercise-induced neuroprotection while HIF2α is needed for dopaminergic neuron survival in the substantia nigra pars compacta | |
P478 | volume | 295 |