Endoglin for targeted cancer treatment

scientific article published on February 2014

Endoglin for targeted cancer treatment is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1023480768
P356DOI10.1007/S11912-013-0365-X
P698PubMed publication ID24445497

P50authorDaniela E. MateiQ79322621
P2093author name stringMichael S Gordon
Francisco Robert
Lee S Rosen
P2860cites workComparative evaluation of microvessel density determined by CD34 or CD105 in benign and malignant gastric lesionsQ79753668
Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in prostatic adenocarcinomaQ79973857
Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in esophageal adenocarcinomaQ81192902
Preoperative plasma endoglin levels predict biochemical progression after radical prostatectomyQ81385868
Differential expression and cytoplasm/membrane distribution of endoglin (CD105) in human tumour cell lines: Implications in the modulation of cell proliferationQ81612146
Endoglin (CD105) as a prognostic factor in head and neck squamous cell carcinomaQ83151095
The risk of developing metastatic disease in colorectal cancer is related to CD105-positive vessel countQ83155632
Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanomaQ24300402
Modes of resistance to anti-angiogenic therapyQ24608005
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasisQ24608039
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Sorafenib in advanced hepatocellular carcinomaQ27861075
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementQ27861120
Defective angiogenesis in mice lacking endoglinQ28144833
Antiangiogenic therapy of established tumors in human skin/severe combined immunodeficiency mouse chimeras by anti-endoglin (CD105) monoclonal antibodies, and synergy between anti-endoglin antibody and cyclophosphamideQ28203483
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancerQ28278736
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
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Regional effects of an antivascular endothelial growth factor receptor monoclonal antibody on receptor phosphorylation and apoptosis in human 253J B-V bladder cancer xenograftsQ31087014
Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinomaQ33241639
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206Q33813718
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survivalQ34021957
Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodiesQ34540047
Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria.Q34579127
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.Q34633525
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Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent miceQ35157425
Anti-endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculatureQ35201283
Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growthQ35314203
Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105.Q35587248
A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancerQ36205086
Hereditary Haemorrhagic Telangiectasia (HHT): genetic and molecular aspects.Q36447285
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic disseminationQ36694132
The VHL/HIF axis in clear cell renal carcinomaQ36872295
Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic miceQ36941168
Endoglin (CD105): a marker of tumor vasculature and potential target for therapyQ37125562
Mean overall survival gain with aflibercept plus FOLFIRI vs placebo plus FOLFIRI in patients with previously treated metastatic colorectal cancerQ37214304
Benign mesenchymal stromal cells in human sarcomas.Q37287076
ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumoursQ37295765
Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosisQ37340349
Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6.Q37404033
Pathways mediating VEGF-independent tumor angiogenesisQ37652164
Endoglin for tumor imaging and targeted cancer therapy.Q38074721
In vitro and in vivo effects of an anti-mouse endoglin (CD105)-immunotoxin on the early stages of mouse B16MEL4A5 melanoma tumoursQ39257411
Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesodermQ39747265
Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.Q39753483
Assessment of the prognostic significance of endoglin (CD105) in clear cell renal cell carcinoma using automated image analysisQ40013934
Sarcoma derived from cultured mesenchymal stem cellsQ40220522
CD105 prevents apoptosis in hypoxic endothelial cellsQ42441203
Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathwaysQ42525897
CD105 expression is an independent predictor of survival in patients with endometrial cancerQ43405195
Endoglin expression is associated with poor oncologic outcome in oral and oropharyngeal carcinomaQ43625943
Elevated plasma endoglin (CD105) predicts decreased response and survival in a metastatic breast cancer trial of hormone therapyQ46179881
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancerQ46892024
Differential vascular and transcriptional responses to anti-vascular endothelial growth factor antibody in orthotopic human pancreatic cancer xenograftsQ47594304
Hereditary hemorrhagic telangiectasia: clinical features in ENG and ALK1 mutation carriers.Q48227582
Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: comparison with an anti-CD31 monoclonal antibody.Q48760414
Endoglin has a crucial role in blood cell-mediated vascular repair.Q52002581
Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study.Q53424963
The prognostic value of endoglin (CD105) expression in ovarian carcinoma.Q53596396
Synergy between anti-endoglin (CD105) monoclonal antibodies and TGF-beta in suppression of growth of human endothelial cells.Q53647266
Identification of a tumor-initiating stem cell population in human renal carcinomasQ58831537
AngiogenesisQ67897095
Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell lineQ68098157
Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrowQ72169083
A case of angiosarcoma of the breastQ73342562
Breast carcinoma: vascular density determined using CD105 antibody correlates with tumor prognosisQ74462138
Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodiesQ74484401
Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibodyQ77161616
Expression of transforming growth factor beta and transforming growth factor beta receptors on AIDS-associated Kaposi's sarcomaQ77555172
Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapyQ77555510
P433issue2
P304page(s)365
P577publication date2014-02-01
P1433published inCurrent Oncology ReportsQ2264969
P1476titleEndoglin for targeted cancer treatment
P478volume16