| scholarly article | Q13442814 |
| P50 | author | Ajai K. Tripathi | Q42773496 |
| P2093 | author name string | Neena Singh | |
| Matthew K McElwee | |||
| Amber Beserra | |||
| Swati Haldar | |||
| Katharine Horback | |||
| P2860 | cites work | DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation | Q21146396 |
| Missing pieces in the Parkinson's disease puzzle | Q22251063 | ||
| Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
| Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 | Q24290518 | ||
| Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration | Q24298689 | ||
| Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function | Q24306074 | ||
| Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism | Q24309753 | ||
| Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism | Q24321359 | ||
| Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease | Q24336655 | ||
| Hereditary early-onset Parkinson's disease caused by mutations in PINK1 | Q24337084 | ||
| Generating a prion with bacterially expressed recombinant prion protein | Q24626352 | ||
| Prions | Q24633319 | ||
| Mechanisms of rotenone-induced proteasome inhibition | Q24633912 | ||
| Formation of native prions from minimal components in vitro | Q24676353 | ||
| The Steap proteins are metalloreductases | Q24681553 | ||
| Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders | Q26850298 | ||
| Update on genetics of parkinsonism | Q27022841 | ||
| Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
| alpha-Synuclein locus triplication causes Parkinson's disease | Q27860533 | ||
| Alpha-synuclein in Lewy bodies | Q27860680 | ||
| Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase | Q28116395 | ||
| Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice | Q28131756 | ||
| Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure | Q28145614 | ||
| Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology | Q28478072 | ||
| Development and characterization of a new Parkinson's disease model resulting from impaired autophagy | Q28511536 | ||
| Mitochondrial dysfunction and oxidative damage in parkin-deficient mice | Q28593859 | ||
| The ferritins: molecular properties, iron storage function and cellular regulation | Q28609366 | ||
| Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease | Q28610102 | ||
| The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
| Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease | Q29547175 | ||
| Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin | Q29547423 | ||
| Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy | Q29614178 | ||
| Alpha-synuclein locus duplication as a cause of familial Parkinson's disease | Q29614762 | ||
| Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin | Q29615684 | ||
| Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice | Q29620597 | ||
| Effect of mitochondrial complex I inhibition on Fe-S cluster protein activity | Q30402672 | ||
| Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. | Q30440422 | ||
| Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions | Q30492360 | ||
| Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic | Q30525658 | ||
| Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort | Q33249091 | ||
| Neuroprotective effect of the natural iron chelator, phytic acid in a cell culture model of Parkinson's disease | Q33318606 | ||
| Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells | Q33323232 | ||
| Abnormal brain iron homeostasis in human and animal prion disorders | Q33417668 | ||
| Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport | Q33476856 | ||
| Paradoxical role of prion protein aggregates in redox-iron induced toxicity | Q33631161 | ||
| GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein | Q36825286 | ||
| Redox imbalance in Parkinson's disease | Q36899782 | ||
| Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease | Q36985218 | ||
| Twenty years of metallo-neurobiology: where to now? | Q36997762 | ||
| A delicate balance: Iron metabolism and diseases of the brain. | Q37023585 | ||
| Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis | Q37087487 | ||
| Comparative profiling of highly enriched 22L and Chandler mouse scrapie prion protein preparations | Q37091434 | ||
| A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. | Q37258755 | ||
| Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein | Q37285506 | ||
| Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis | Q37315448 | ||
| Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases | Q37376532 | ||
| Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila. | Q37408628 | ||
| Autophagy, prion infection and their mutual interactions | Q37600571 | ||
| Prion protein and metal interaction: physiological and pathological implications | Q37600574 | ||
| Prions: protein aggregation and infectious diseases | Q37605469 | ||
| Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics | Q37742819 | ||
| Could a dysfunction of ferritin be a determinant factor in the aetiology of some neurodegenerative diseases? | Q37743788 | ||
| Milestones in PD genetics | Q37882589 | ||
| The neuropathology of genetic Parkinson's disease | Q37997386 | ||
| Molecular mechanisms of amyloid oligomers toxicity | Q38005284 | ||
| Kinases and kinase signaling pathways: potential therapeutic targets in Parkinson's disease | Q38019676 | ||
| Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences | Q38021865 | ||
| Prion propagation, toxicity and degradation | Q38021894 | ||
| Mutant prion protein D202N associated with familial prion disease is retained in the endoplasmic reticulum and forms 'curly' intracellular aggregates | Q38601340 | ||
| Prions disturb post-Golgi trafficking of membrane proteins | Q39152094 | ||
| Prion protein conversion induced by trivalent iron in vesicular trafficking | Q39193299 | ||
| The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1. | Q39402118 | ||
| α-Synuclein aggregation and transmission are enhanced by leucine-rich repeat kinase 2 in human neuroblastoma SH-SY5Y cells | Q39514955 | ||
| Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease | Q39524732 | ||
| Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. | Q39655865 | ||
| Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent | Q39744987 | ||
| The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy | Q39754547 | ||
| Ferroportin 1 but not hephaestin contributes to iron accumulation in a cell model of Parkinson's disease | Q39774883 | ||
| Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells | Q39848404 | ||
| Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy | Q39889005 | ||
| Autophagy induction by trehalose counteracts cellular prion infection | Q39889113 | ||
| Pathogenic mutations in the glycosylphosphatidylinositol signal peptide of PrP modulate its topology in neuroblastoma cells | Q40004860 | ||
| Mitochondrial association of alpha-synuclein causes oxidative stress | Q40005336 | ||
| Hemin interactions and alterations of the subcellular localization of prion protein | Q40070117 | ||
| The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery. | Q40082182 | ||
| The anticancer drug imatinib induces cellular autophagy. | Q40165123 | ||
| Increased susceptibility to oxidative stress in scrapie-infected neuroblastoma cells is associated with intracellular iron status | Q40386248 | ||
| Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells | Q40415370 | ||
| Changed iron regulation in scrapie-infected neuroblastoma cells. | Q40458622 | ||
| Doxycycline and protein folding agents rescue the abnormal phenotype of familial CJD H187R in a cell model | Q40573182 | ||
| Prion peptide 106-126 as a model for prion replication and neurotoxicity | Q40744268 | ||
| Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro | Q41646793 | ||
| alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease | Q41676981 | ||
| Mitochondrial complex I deficiency in Parkinson's disease | Q41821730 | ||
| Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice | Q42181538 | ||
| Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo | Q42391404 | ||
| Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1. | Q43188522 | ||
| Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
| Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis | Q43579795 | ||
| Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease | Q43624453 | ||
| Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells | Q43758292 | ||
| Conformational behavior of human alpha-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T. | Q44214168 | ||
| Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity | Q44251270 | ||
| Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons | Q44258606 | ||
| Aggresome formation by mutant prion proteins: the unfolding role of proteasomes in familial prion disorders | Q44318037 | ||
| Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system | Q44438522 | ||
| LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity | Q44483853 | ||
| Redox metals and oxidative abnormalities in human prion diseases | Q44823992 | ||
| A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's d | Q33644307 | ||
| Binding of alpha-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes. | Q33665421 | ||
| Prion protein regulates iron transport by functioning as a ferrireductase | Q33744807 | ||
| The transgenic overexpression of alpha-synuclein and not its related pathology associates with complex I inhibition. | Q33748087 | ||
| Alpha-synuclein is a cellular ferrireductase | Q33798034 | ||
| Redox control of prion and disease pathogenesis | Q33830151 | ||
| Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders | Q33847248 | ||
| Iron content of ferritin modulates its uptake by intestinal epithelium: implications for co-transport of prions | Q33864786 | ||
| Protein aggregation diseases: pathogenicity and therapeutic perspectives | Q34101110 | ||
| Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. | Q34309906 | ||
| Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis | Q34407914 | ||
| In vitro generation of infectious scrapie prions. | Q34413661 | ||
| Cell-specific metabolism and pathogenesis of transmembrane prion protein | Q34520060 | ||
| Deadly encounter: ubiquitin meets apoptosis | Q34522855 | ||
| Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging | Q34556311 | ||
| Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics | Q34621634 | ||
| TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease | Q34692945 | ||
| Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro. | Q34781079 | ||
| alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity | Q34980191 | ||
| α-Synuclein impairs macroautophagy: implications for Parkinson's disease. | Q35005567 | ||
| Prion propagation in cultured cells. | Q35548980 | ||
| How to make a glycoinositol phospholipid anchor | Q35557536 | ||
| Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology | Q35745646 | ||
| alpha-synuclein promotes mitochondrial deficit and oxidative stress | Q35745729 | ||
| Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains | Q35777814 | ||
| Mitochondrial dysfunction in genetic animal models of Parkinson's disease | Q35799109 | ||
| Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis | Q35949128 | ||
| Chelators in the treatment of iron accumulation in Parkinson's disease | Q36056203 | ||
| Molecular pathophysiology of Parkinson's disease | Q36196507 | ||
| Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation | Q36383567 | ||
| Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases | Q36543922 | ||
| Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain | Q36727241 | ||
| Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells | Q36820108 | ||
| ??? | Q64767196 | ||
| Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. | Q45188909 | ||
| Individual dopaminergic neurons show raised iron levels in Parkinson disease. | Q45305197 | ||
| Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease | Q46084408 | ||
| Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid (DA) on the conversion of PrPC to PrPres | Q46367797 | ||
| α-Synuclein expression is modulated at the translational level by iron | Q46496494 | ||
| Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers | Q46765690 | ||
| Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function | Q46797053 | ||
| Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. | Q46884563 | ||
| Identification of a proteinase K resistant protein for use as an internal positive control marker in PrP Western blotting | Q48253971 | ||
| Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication | Q48298527 | ||
| Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy | Q48342277 | ||
| Identification of cryptic nuclear localization signals in the prion protein | Q48350176 | ||
| Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease | Q48353748 | ||
| Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism | Q48742196 | ||
| Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains | Q48789036 | ||
| Expression of divalent metal transporter 1 in primary hippocampal neurons: reconsidering its role in non-transferrin-bound iron influx. | Q50507011 | ||
| Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. | Q51387140 | ||
| Copper- and iron-induced differential fibril formation in α-synuclein: TEM study | Q57459956 | ||
| Prion protein expression level alters regional copper, iron and zinc content in the mouse brain | Q57610257 | ||
| Interaction of α-Synuclein with Divalent Metal Ions Reveals Key Differences: A Link between Structure, Binding Specificity and Fibrillation Enhancement | Q58484316 | ||
| The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome | Q59505868 | ||
| Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein | Q59505870 | ||
| Prion Protein Aggregation Reverted by Low Temperature in Transfected Cells Carrying a Prion Protein Gene Mutation | Q59505876 | ||
| The Pivotal Role of Iron in NF-kappaB Activation and Nigrostriatal Dopaminergic Neurodegeneration: Prospects for Neuroprotection in Parkinson's Disease with Iron Chelators | Q59508530 | ||
| Mitochondrial dysfunction in Parkinson's disease | Q60290965 | ||
| Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains | Q61714001 | ||
| Sequestration of iron by Lewy bodies in Parkinson's disease | Q64771847 | ||
| Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro | Q64865343 | ||
| Abnormalities of the electron transport chain in idiopathic Parkinson's disease | Q69361952 | ||
| Neuroprotective effect of the iron chelator desferrioxamine against MPP+ toxicity on striatal dopaminergic terminals | Q72996386 | ||
| Increased ferric iron content and iron-induced oxidative stress in the brains of scrapie-infected mice | Q73200093 | ||
| Association study between iron-related genes polymorphisms and Parkinson's disease | Q74519525 | ||
| Prion peptide 106-126 modulates the aggregation of cellular prion protein and induces the synthesis of potentially neurotoxic transmembrane PrP | Q77079983 | ||
| The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element | Q79838827 | ||
| Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage | Q80107802 | ||
| Midbrain iron content in early Parkinson disease: a potential biomarker of disease status | Q80437646 | ||
| The relevance of iron in the pathogenesis of Parkinson's disease | Q82785179 | ||
| P433 | issue | 3 | |
| P921 | main subject | neurodegeneration | Q1755122 |
| prion protein family | Q24724413 | ||
| P304 | page(s) | 471-484 | |
| P577 | publication date | 2014-02-27 | |
| P1433 | published in | Antioxidants & Redox Signaling | Q4775078 |
| P1476 | title | Iron in neurodegenerative disorders of protein misfolding: a case of prion disorders and Parkinson's disease | |
| P478 | volume | 21 |
| Q38915163 | Coherent and Contradictory Facts, Feats and Fictions Associated with Metal Accumulation in Parkinson's Disease: Epicenter or Outcome, Yet a Demigod Question |
| Q34081999 | Deficiency of prion protein induces impaired autophagic flux in neurons |
| Q58740022 | Differential expression of miRNA 155 and miRNA 146a in Parkinson's disease patients |
| Q34585744 | Eryptosis as a marker of Parkinson's disease |
| Q49388205 | Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases |
| Q41957300 | Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease |
| Q40075661 | Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders. |
| Q55285231 | Prion protein modulates glucose homeostasis by altering intracellular iron. |
| Q64105372 | Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity |
| Q30973484 | The Chemistry of Neurodegeneration: Kinetic Data and Their Implications |
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| Q38241438 | α-Synuclein Misfolding Versus Aggregation Relevance to Parkinson's Disease: Critical Assessment and Modeling |
| Q42373959 | α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's disease |
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