S-Nitrosylation in Alzheimer's disease

scientific article published on 25 March 2014

S-Nitrosylation in Alzheimer's disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1027830391
P356DOI10.1007/S12035-014-8672-2
P698PubMed publication ID24664522
P5875ResearchGate publication ID261069651

P50authorLan TanQ66911182
Jin-Tai YuQ37837814
P2093author name stringQing-Fei Zhao
P2860cites workInfluence of APOE genotype and the presence of Alzheimer's pathology on synaptic membrane lipids of human brains.Q53348326
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.Q53381705
Nitrite-Mediated S -Nitrosylation of Caspase-3 Prevents Hypoxia-Induced Endothelial Barrier DysfunctionQ63370764
S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retractionQ80808704
Nitric oxide vs insulin secretion, action and clearanceQ86548007
Detection and localization of methionine sulfoxide residues of specific proteins in brain tissueQ86979647
Site-specific and redox-controlled S-nitrosation of thioredoxinQ24603869
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptideQ24612303
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosisQ24652801
Structural basis of tubulin tyrosination by tubulin tyrosine ligaseQ27676036
Hsp90 is regulated by a switch point in the C-terminal domainQ27933174
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegenerationQ28242222
Mitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer's diseaseQ28260038
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapyQ28282855
Mitochondrial fragmentation in neurodegenerationQ28284588
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic lossQ28293023
Difficulties in generating specific antibodies for immunohistochemical detection of nitrosylated tubulinsQ28534425
GAPDH mediates nitrosylation of nuclear proteinsQ28569676
GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylationQ28570143
Impaired balance of mitochondrial fission and fusion in Alzheimer's diseaseQ28854335
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeuticsQ29614972
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injuryQ29616550
S-Nitrosylation of mitochondrial caspasesQ30441958
MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cellsQ30539497
Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndromeQ30654401
Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylationQ33553407
GPS-SNO: computational prediction of protein S-nitrosylation sites with a modified GPS algorithmQ33619142
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activityQ33673430
Resin-assisted enrichment of thiols as a general strategy for proteomic profiling of cysteine-based reversible modificationsQ33684459
Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted captureQ33936994
Superoxide dismutases: role in redox signaling, vascular function, and diseasesQ34176532
GAPDH regulates cellular heme insertion into inducible nitric oxide synthaseQ34241252
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse modelQ34276376
Identification of S-nitrosylated targets of thioredoxin using a quantitative proteomic approachQ34433626
Chaperones increase association of tau protein with microtubulesQ34470626
Carbonic anhydrase gating of attention: memory therapy and enhancementQ34519405
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductaseQ34583665
Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formationQ34608269
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and diseaseQ34651972
S-nitrosylation of ApoE in Alzheimer's diseaseQ34861154
Hsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent processQ35003199
Proteomics screening of molecular targets of curcumin in mouse brainQ35084098
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95Q35234999
Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formationQ35421560
Post-translational modifications of Hsp90 and their contributions to chaperone regulationQ35581165
Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiationQ35647685
Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motifQ35758244
Mitochondrial ubiquitin ligase MITOL blocks S-nitrosylated MAP1B-light chain 1-mediated mitochondrial dysfunction and neuronal cell deathQ35787066
Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular functionQ35837215
Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic functionQ35839831
Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortexQ36115080
Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradationQ36335851
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's diseaseQ36375845
Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer's disease mice modelQ36541713
Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stressQ36620873
S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic strokeQ36637278
Isoforms of nitric oxide synthase Characterization and purification from different cell typesQ36700509
S-Nitrosylation and uncompetitive/fast off-rate (UFO) drug therapy in neurodegenerative disorders of protein misfoldingQ36790561
Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylationQ36792131
nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challengeQ36847715
X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axisQ37012399
The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?Q37134820
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's diseaseQ37140171
GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in ratsQ37148302
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.Q37200867
SOD2 in mitochondrial dysfunction and neurodegenerationQ37262897
Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: implications for synaptic dysfunction and neuronal damageQ37302845
Korean Red Ginseng protects endothelial cells from serum-deprived apoptosis by regulating Bcl-2 family protein dynamics and caspase S-nitrosylationQ37303179
Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degenerationQ37404781
Reduced VDAC1 protects against Alzheimer's disease, mitochondria, and synaptic deficienciesQ37586163
Estradiol and tamoxifen differentially regulate a plasmalemmal voltage-dependent anion channel involved in amyloid-beta induced neurotoxicityQ37847495
Cdk5: a multifaceted kinase in neurodegenerative diseasesQ37970544
Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiologyQ38010956
Emerging role of protein-protein transnitrosylation in cell signaling pathwaysQ38015510
Thioredoxin and thioredoxin reductase in relation to reversible S-nitrosylationQ38018964
S-nitrosation/denitrosation in cardiovascular pathologies: facts and concepts for the rational design of S-nitrosothiols.Q38037749
Endoplasmic reticulum dysfunction in neurological diseaseQ38067205
The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.Q38092945
Aberrant protein s-nitrosylation in neurodegenerative diseasesQ38110376
Autophagy and apoptosis dysfunction in neurodegenerative disordersQ38161278
S-nitrosylation of Cdk5: potential implications in amyloid-β-related neurotoxicity in Alzheimer diseaseQ39330967
Plasma aβ: a possible missing link between Alzheimer disease and diabetesQ39348524
Enhanced expression of the voltage-dependent anion channel 1 (VDAC1) in Alzheimer's disease transgenic mice: an insight into the pathogenic effects of amyloid-β.Q39647115
Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylationQ40910444
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's diseaseQ41945324
Improvements in a Mouse Model of Alzheimer's Disease Through SOD2 Overexpression are Due to Functional and Not Structural AlterationsQ42051594
Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2Q42132981
Cytoplasmic superoxide radical: a possible contributing factor to intracellular Aβ oligomerization in Alzheimer diseaseQ42276130
Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell DeathQ42530430
S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1-GAPDH death cascadeQ42545938
S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development.Q42845661
The unfolded protein response and proteostasis in Alzheimer disease: preferential activation of autophagy by endoplasmic reticulum stress.Q42854216
Temperature control can abolish anesthesia-induced tau hyperphosphorylation and partly reverse anesthesia-induced cognitive impairment in old miceQ43433287
Differential S-nitrosylation of proteins in Alzheimer's disease.Q44242702
TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han ChineseQ44624389
Characterization of the S-denitrosation activity of protein disulfide isomeraseQ45195802
XIAP regulates caspase activity in degenerating axonsQ46813160
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approachQ46868947
SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese populationQ48649324
Protective effects of intraperitoneal injection of TAT-SOD against focal cerebral ischemia/reperfusion injury in rats.Q48854392
Involvement of insulin-degrading enzyme in insulin- and atrial natriuretic peptide-sensitive internalization of amyloid-β peptide in mouse brain capillary endothelial cellsQ49155032
Potential effect of S-nitrosylated protein disulfide isomerase on mutant SOD1 aggregation and neuronal cell death in amyotrophic lateral sclerosis.Q51779212
Sting of Alzheimer's failures offset by upcoming prevention trials.Q53332313
P433issue1
P921main subjectAlzheimer's diseaseQ11081
P304page(s)268-280
P577publication date2014-03-25
P1433published inMolecular NeurobiologyQ15716645
P1476titleS-Nitrosylation in Alzheimer's disease
P478volume51

Reverse relations

cites work (P2860)
Q88406300Computational Prediction and Analysis of Associations between Small Molecules and Binding-Associated S-Nitrosylation Sites
Q39387054Cysteines as Redox Molecular Switches and Targets of Disease
Q58122164Fighting the Cause of Alzheimer's and GNE Myopathy
Q36997402High-throughput endogenous measurement of S-nitrosylation in Alzheimer's disease using oxidized cysteine-selective cPILOT.
Q38809142Nanoparticles as potential clinical therapeutic agents in Alzheimer's disease: focus on selenium nanoparticles
Q40027781Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice
Q30393354Proteomic approaches to quantify cysteine reversible modifications in aging and neurodegenerative diseases
Q38904876Reversible redox modifications in the microglial proteome challenged by beta amyloid.
Q55000550Roles of Gasotransmitters in Synaptic Plasticity and Neuropsychiatric Conditions.
Q93083881Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade
Q98513674Systems biology reveals reprogramming of the S-nitroso-proteome in the cortical and striatal regions of mice during aging process

Search more.