T-cell selection and intestinal homeostasis

scientific article published on May 2014

T-cell selection and intestinal homeostasis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/IMR.12171
P932PMC publication ID4028094
P698PubMed publication ID24712459

P50authorChyi-Song HsiehQ38323816
Benjamin SolomonQ59667795
P2093author name stringTeresa L Ai
P2860cites workFOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndromeQ84761786
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cellsQ85634389
A frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat functionQ24314628
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient miceQ24523182
Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestineQ24609125
Human nutrition, the gut microbiome and the immune systemQ24620449
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversityQ24622687
Generation of pathogenic T(H)17 cells in the absence of TGF-β signallingQ24625230
Essential role for CD103 in the T cell-mediated regulation of experimental colitisQ24646106
Innate immunity and intestinal microbiota in the development of Type 1 diabetesQ24647312
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestineQ24648636
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanismsQ24673863
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune systemQ24680733
OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subsetQ24682576
Plasticity of T reg at infected sites.Q27691747
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
Induction of intestinal Th17 cells by segmented filamentous bacteriaQ28131638
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseasesQ28131810
Regulatory T cells exert checks and balances on self tolerance and autoimmunityQ28267935
T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2Q28274670
Herpesvirus latency confers symbiotic protection from bacterial infectionQ28302729
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogensQ28509751
GPR15-mediated homing controls immune homeostasis in the large intestine mucosaQ28510063
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptorQ28593665
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 geneQ28593669
Induction of colonic regulatory T cells by indigenous Clostridium speciesQ29547701
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cellsQ29614271
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiotaQ29614272
Differentiation of effector CD4 T cell populations (*)Q29614838
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidQ29615586
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasisQ29616351
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cellsQ29618126
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiotaQ29618128
Retinoic acid imprints gut-homing specificity on T cellsQ29619126
Molecular antagonism and plasticity of regulatory and inflammatory T cell programsQ29619478
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acidQ29619479
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteriaQ29619620
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiotaQ29619977
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generationQ29620116
Intestinal homeostasis and its breakdown in inflammatory bowel diseaseQ29620336
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearanceQ29620412
Regulatory T cells: mechanisms of differentiation and functionQ29620731
Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph nodeQ30438088
Regulation of intestinal epithelial barrier function by TGF-beta 1. Evidence for its role in abrogating the effect of a T cell cytokine.Q30465882
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagementQ33265418
German outbreak of Escherichia coli O104:H4 associated with sproutsQ33397821
Commensal bacteria at the interface of host metabolism and the immune systemQ33578547
Microbial control of regulatory and effector T cell responses in the gut.Q33699119
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responsesQ33830564
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fateQ33908130
Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentationQ33970555
Immune adaptations that maintain homeostasis with the intestinal microbiotaQ34100501
The human gut microbiome: ecology and recent evolutionary changesQ34193464
A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiotaQ34243359
Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-toleranceQ34503328
Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanismsQ34570917
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulationQ34580976
Antigen-specific peripheral shaping of the natural regulatory T cell populationQ34601484
Intraclonal competition limits the fate determination of regulatory T cells in the thymusQ34607464
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cellsQ34617154
Plasticity of CD4+ T cell lineage differentiation.Q34982725
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.Q35006074
Modulation of immune homeostasis by commensal bacteriaQ35069784
Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.Q35091226
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cellsQ35102340
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi CellsQ35117509
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppressionQ37273329
Pattern recognition receptors and control of adaptive immunityQ37361471
TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizesQ37377465
How diverse--CD4 effector T cells and their functionsQ37502276
Role of autophagy and autophagy genes in inflammatory bowel diseaseQ37608036
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signalsQ37734574
Bacteroides spp. and diarrheaQ37778975
Regulatory T cell lineage commitment in the thymusQ37898295
Intestinal dendritic cells: their role in intestinal inflammation, manipulation by the gut microbiota and differences between mice and men.Q38076962
Transepithelial antigen delivery in the small intestine: different paths, different outcomesQ38079085
Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defenseQ38080684
Transcriptional control of dendritic cell developmentQ38144241
Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbesQ38163162
An essential role of the transcription factor GATA-3 for the function of regulatory T cellsQ38586280
FoxP3+RORgammat+ T helper intermediates display suppressive function against autoimmune diabetesQ39752246
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammationQ41762357
Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.Q43081763
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.Q45299244
Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.Q46099764
Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.Q47777664
Regulatory T cells: recommendations to simplify the nomenclature.Q48624465
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.Q48819558
Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells.Q50530610
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.Q51769095
Expression of Helios in Peripherally Induced Foxp3+ Regulatory T CellsQ56888758
Impaired regulatory T cell function in germ-free miceQ56901969
Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell ResponsesQ60556933
Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient miceQ63363242
Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigensQ72803264
Arthritis provoked by linked T and B cell recognition of a glycolytic enzymeQ73216181
Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipientsQ73271356
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptideQ73688337
CD4+ T-cells in the regulation of inflammatory responses in the intestineQ74552673
Control of intestinal inflammation by regulatory T cellsQ77291202
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammationQ77855399
Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditionsQ80242000
Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasisQ80430658
Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cellsQ81224627
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responsesQ81305086
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cellsQ35197906
Peripheral education of the immune system by colonic commensal microbiota.Q35341308
GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in miceQ35484886
Influence of intestinal bacteria on induction of regulatory T cells: lessons from a transfer model of colitisQ35597887
Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.Q35679555
Immune responses that adapt the intestinal mucosa to commensal intestinal bacteriaQ36122642
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alphaQ36151999
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.Q36193512
Thymic emigration revisitedQ36229138
A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.Q36275699
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivoQ36278029
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cellsQ36278051
Induction and molecular signature of pathogenic TH17 cellsQ36283752
Extrathymically generated regulatory T cells control mucosal TH2 inflammationQ36359813
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
Peripheral autoantigen induces regulatory T cells that prevent autoimmunityQ36367859
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetesQ36399048
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.Q36399104
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cellsQ36509846
Th17: an effector CD4 T cell lineage with regulatory T cell tiesQ36510274
Regulatory T cells in the peripheryQ36563523
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.Q36693820
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cellsQ36699777
Re(de)fining the dendritic cell lineage.Q36818027
Thymus-derived regulatory T cells contribute to tolerance to commensal microbiotaQ37011757
Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cellsQ37013654
CD4(+) T-cell subsets in intestinal inflammationQ37076943
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticityQ37100901
mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell functionQ37137541
Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism.Q37194987
Acute gastrointestinal infection induces long-lived microbiota-specific T cell responsesQ37200518
P433issue1
P304page(s)60-74
P577publication date2014-05-01
P1433published inImmunological ReviewsQ15724582
P1476titleT-cell selection and intestinal homeostasis
P478volume259

Reverse relations

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