β-Glucuronidase activity and mitochondrial dysfunction: the sites where flavonoid glucuronides act as anti-inflammatory agents

scientific article published on 12 April 2014

β-Glucuronidase activity and mitochondrial dysfunction: the sites where flavonoid glucuronides act as anti-inflammatory agents is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3164/JCBN.14-9
P8608Fatcat IDrelease_2dc3djtwzjaujivgtjpvdkazmm
P932PMC publication ID4042145
P698PubMed publication ID24895476
P5875ResearchGate publication ID262844579

P2093author name stringYoshichika Kawai
P2860cites workThe selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1Q24300456
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
A role for mitochondria in NLRP3 inflammasome activationQ28131794
Loss of autophagy in the central nervous system causes neurodegeneration in miceQ28131804
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasomeQ29547419
A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic propertiesQ31121766
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagyQ33588721
Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetinQ33947719
Beneficial effects of green tea--a review.Q33994592
Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux areaQ34065159
Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.Q34199948
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failureQ34270939
Flavonoid metabolites in human plasma and urine after the consumption of red onions: analysis by liquid chromatography with photodiode array and full scan tandem mass spectrometric detectionQ34553367
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly StudyQ34726987
Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophagesQ35049292
In vitro biological properties of flavonoid conjugates found in vivo.Q36203524
Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulationQ37022244
Distribution and functions of catechol-O-methyltransferase proteins: do recent findings change the picture?Q37811520
Antioxidant capacity of albumin-bound quercetin metabolites after onion consumption in humansQ38504428
(-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechinsQ39957019
Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries: implication in the anti-atherosclerotic mechanism of dietary flavonoidsQ40024441
Potential health effects of the dietary flavonol quercetinQ40993456
Autophagy-deficient mice develop multiple liver tumorsQ42099409
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemiaQ42442810
Protein kinase C and intracellular pH regulate zymosan-induced lysosomal enzyme secretion in macrophagesQ42478630
Suppressive effect of cocoa powder on atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbitsQ43562499
Flavonoid glucuronides are substrates for human liver beta-glucuronidaseQ43713502
Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammationQ43805176
Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetinQ43866518
Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries studyQ43885250
Effect of quercetin conjugates on vascular permeability and expression of adhesion moleculesQ45210227
Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbitsQ46389944
Chocolate as a source of tea flavonoidsQ46573827
Glucuronidase deconjugation in inflammationQ46884258
Determination of green tea catechins in human plasma using liquid chromatography-electrospray ionization mass spectrometryQ46972788
Effects of lysophosphatidylcholine on monolayer cell permeability of human coronary artery endothelial cells.Q50752517
Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging.Q53354093
Analysis of plasma and urinary tea polyphenols in human subjectsQ53463485
Dietary flavonoids and cancer risk in the Zutphen elderly studyQ53474829
Effects of cacao liquor polyphenols on the susceptibility of low-density lipoprotein to oxidation in hypercholesterolemic rabbits.Q54000303
PGBX, a prostagandin derivative, mimics the action of the calcium ionophore A23187 on human neutrophilsQ57731299
Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen studyQ71077406
Preventive effects of green tea against liver oxidative DNA damage and hepatotoxicity in rats treated with 2-nitropropaneQ71818477
Intake of flavonoids and lung cancerQ73365478
Effect of a conjugated quercetin metabolite, quercetin 3-glucuronide, on lipid hydroperoxide-dependent formation of reactive oxygen species in differentiated PC-12 cellsQ79173299
Chemically modified low density lipoproteins as inducers of enzyme release from macrophagesQ93573067
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectflavonoid glucuronideQ116034820
P304page(s)145-150
P577publication date2014-04-12
P1433published inJournal of Clinical Biochemistry and NutritionQ24039135
P1476titleβ-Glucuronidase activity and mitochondrial dysfunction: the sites where flavonoid glucuronides act as anti-inflammatory agents
P478volume54

Reverse relations

cites work (P2860)
Q336789035,7-Dihydroxyflavone Analogues May Regulate Lipopolysaccharide-Induced Inflammatory Responses by Suppressing IκBα-Linked Akt and ERK5 Phosphorylation in RAW 264.7 Macrophages
Q28071627At the interface of antioxidant signalling and cellular function: Key polyphenol effects
Q92359638Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence
Q48161759Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis
Q39504039Natural Biflavonoids Modulate Macrophage-Oxidized LDL Interaction In Vitro and Promote Atheroprotection In Vivo
Q38450512Proinflammatory Pathways: The Modulation by Flavonoids.
Q90755253The Influence of In Vivo Metabolic Modifications on ADMET Properties of Green Tea Catechins-In Silico Analysis
Q49951711Therapeutic charm of quercetin and its derivatives: a review of research and patents.

Search more.