Invadopodia, regulation, and assembly in cancer cell invasion

scientific article

Invadopodia, regulation, and assembly in cancer cell invasion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/15419061.2014.923845
P698PubMed publication ID24930891
P5875ResearchGate publication ID263131416

P50authorBechara A SaykaliQ60198602
P2093author name stringMirvat El-Sibai
P2860cites workNovel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activityQ24316184
Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motilityQ24338202
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The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formationQ24647032
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Cellular motility driven by assembly and disassembly of actin filamentsQ27860676
The phosphoinositide 3-kinase pathwayQ27860738
The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cellsQ28180409
Inhibition of calpain stabilises podosomes and impairs dendritic cell motilityQ28242155
Rho GTPases and actin dynamics in membrane protrusions and vesicle traffickingQ28261534
Assembly and biological role of podosomes and invadopodiaQ28272503
Mapping proteolytic cancer cell-extracellular matrix interfacesQ37207020
FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasionQ37237616
The cytoskeleton and cancerQ37372562
Actin dynamics at the leading edge: from simple machinery to complex networks.Q37598394
Fascin: Invasive filopodia promoting metastasisQ37780451
Life at the leading edgeQ37894186
PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxisQ39516931
Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assemblyQ39971306
Actin dynamics at sites of extracellular matrix degradation.Q40225791
Lamellipodia architecture: actin filament turnover and the lateral flow of actin filaments during motilityQ40627386
Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomesQ41676407
Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasisQ42127808
A signalling cascade involving PKC, Src and Cdc42 regulates podosome assembly in cultured endothelial cells in response to phorbol esterQ46921342
PI(3)Kγ has an important context-dependent role in neutrophil chemokinesisQ57006266
Local degradation of fibronectin at sites of expression of the transforming gene product pp60srcQ59056943
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodiaQ28300785
Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cellsQ28301550
Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110Q28391904
Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashionQ28511276
N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cellsQ28571875
Arg interacts with cortactin to promote adhesion-dependent cell edge protrusionQ28585696
A nucleator arms race: cellular control of actin assemblyQ29616146
The WASP-WAVE protein network: connecting the membrane to the cytoskeletonQ29616493
Two distinct actin networks drive the protrusion of migrating cellsQ29617078
Phosphoinositide kinasesQ29618047
Spatiotemporal dynamics of RhoA activity in migrating cellsQ29618433
Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradationQ30157203
Sequential signals toward podosome formation in NIH-src cells.Q30157646
The SRC substrate Tks5, podosomes (invadopodia), and cancer cell invasionQ30159706
The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cellsQ30160317
RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cellsQ30487430
Molecular mechanism of Ena/VASP-mediated actin-filament elongation.Q30498103
Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axisQ30536784
Breaking away: matrix remodeling from the leading edgeQ31099586
Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivoQ34090534
Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomesQ34377019
Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cellsQ34452930
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodiaQ34565948
Podosomes in adhesion, migration, mechanosensing and matrix remodeling.Q34785129
Temporal and spatial regulation of chemotaxisQ34984894
Distant metastasis in breast cancer: molecular mechanisms and therapeutic targetsQ35097826
Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formationQ35550765
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathwayQ35670711
Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complexQ35744526
The actin cytoskeleton in normal and pathological cell motilityQ35808816
The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclastsQ36325944
Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virusQ36415878
Mechanisms of gradient sensing and chemotaxis: conserved pathways, diverse regulation.Q36499903
Podosome-type adhesions and focal adhesions, so alike yet so differentQ37140194
The actin cytoskeleton in cancer cell motilityQ37170851
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectinvadopodiaQ3498029
P304page(s)207-212
P577publication date2014-06-16
P1433published inCell Communication & AdhesionQ15709519
P1476titleInvadopodia, regulation, and assembly in cancer cell invasion
P478volume21

Reverse relations

cites work (P2860)
Q89456698A novel function of AAA-ATPase p97/VCP in the regulation of cell motility
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Q90479065Metformin Treatment Inhibits Motility and Invasion of Glioblastoma Cancer Cells
Q48236257PHLDA1 (pleckstrin homology-like domain, family A, member 1) knockdown promotes migration and invasion of MCF10A breast epithelial cells.
Q38293612Pivotal role of pervasive neoplastic and stromal cells reprogramming in circulating tumor cells dissemination and metastatic colonization.
Q38742851Talin2-mediated traction force drives matrix degradation and cell invasion.
Q48010163Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer
Q37306549The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition
Q38671718Tweety-Homolog 1 Drives Brain Colonization of Gliomas.

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