Cells producing their own nemesis: understanding methylglyoxal metabolism

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Cells producing their own nemesis: understanding methylglyoxal metabolism is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/IUB.1324
P698PubMed publication ID25380137
P5875ResearchGate publication ID267929563

P50authorDipshikha ChakravorttyQ47494288
P2093author name stringSangeeta Chakraborty
Kapudeep Karmakar
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LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cellsQ34214122
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Bacterial production of methylglyoxal: a survival strategy or death by misadventure?Q35594323
Focus on molecules: aldose reductaseQ36602108
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors.Q36887564
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Methylglyoxal, glyoxalase 1 and the dicarbonyl proteomeQ37801856
Bacterial glyoxalase enzymes.Q37839319
The glyoxalase system of malaria parasites--implications for cell biology and general glyoxalase researchQ37839320
Methylglyoxal metabolism in trypanosomes and leishmaniaQ37839329
Glyoxalase 1 is up-regulated in hepatocellular carcinoma and is essential for HCC cell proliferationQ39070710
Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.Q39097246
Methylglyoxal induces DNA crosslinks in ECV304 cells via a reactive oxygen species-independent protein carbonylation pathwayQ39185610
A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cellsQ39208002
Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic moleculesQ39316418
Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E.Q39485974
Activity of the Yap1 transcription factor in Saccharomyces cerevisiae is modulated by methylglyoxal, a metabolite derived from glycolysisQ39998794
Metabolism of methylglyoxal in microorganismsQ40078802
Ribose utilization with an excess of mutarotase causes cell death due to accumulation of methylglyoxalQ40212285
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Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.Q41148677
Distinct classes of glyoxalase I: metal specificity of the Yersinia pestis, Pseudomonas aeruginosa and Neisseria meningitidis enzymesQ41461864
Involvement of the detoxifying enzyme lactoylglutathione lyase in Streptococcus mutans aciduricityQ41908424
Production of aminoacetone by Rhodopseudomonas spheroidesQ41993316
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucoseQ42070713
AGEs secreted by bacteria are involved in the inflammatory responseQ42073893
The oxidation of aminoacetone by a species of ArthrobacterQ42156907
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Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death to insulin-producing RINm5f cells.Q42809103
P433issue10
P304page(s)667-678
P577publication date2014-10-01
P1433published inIUBMB LifeQ15764029
P1476titleCells producing their own nemesis: understanding methylglyoxal metabolism
P478volume66

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cites work (P2860)
Q39088773A Genome-Scale Modeling Approach to Quantify Biofilm Component Growth of Salmonella Typhimurium
Q58694598A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
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Q91725238The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes

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