| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Nobuhito Goda | Q52357474 |
| P2093 | author name string | Satoko Shinjo | |
| Tomohiro Suzuki | |||
| Mai Kanai | |||
| Takatomo Arai | |||
| P2860 | cites work | ROS: really involved in oxygen sensing | Q80959540 |
| HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice | Q84900157 | ||
| Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
| Hypoxia-Inducible Factors and the Response to Hypoxic Stress | Q24629323 | ||
| SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells | Q24633565 | ||
| CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease | Q26996634 | ||
| HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression | Q27025886 | ||
| Alcoholic liver disease: pathogenesis and new therapeutic targets | Q27690220 | ||
| Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia | Q28208424 | ||
| Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site | Q28286400 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis | Q28582038 | ||
| Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice | Q28594703 | ||
| Targeting hypoxia in cancer therapy | Q29615491 | ||
| Protein sensors for membrane sterols | Q29617313 | ||
| Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway | Q29617805 | ||
| PPARs and the complex journey to obesity | Q29619271 | ||
| Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
| Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia | Q33312383 | ||
| Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells | Q33556480 | ||
| Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair | Q33565774 | ||
| A novel inhibitor of stearoyl-CoA desaturase-1 attenuates hepatic lipid accumulation, liver injury and inflammation in model of nonalcoholic steatohepatitis | Q44677145 | ||
| Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor | Q45165652 | ||
| Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia | Q45166534 | ||
| Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial | Q46575030 | ||
| Elevated serum aminotransferase levels in children at risk for obstructive sleep apnea | Q46813635 | ||
| Liver enzymes and histology in obese patients with obstructive sleep apnea | Q46843248 | ||
| Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha | Q46968793 | ||
| Obstructive sleep apnea is associated with fatty liver and abnormal liver enzymes: a meta-analysis | Q48173331 | ||
| Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese | Q48296229 | ||
| Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia | Q48420875 | ||
| Relationship between obstructive sleep apnea and liver abnormalities in morbidly obese patients: a prospective study | Q48463175 | ||
| Chronic intermittent hypoxia predisposes to liver injury | Q48473495 | ||
| Chronic liver injury during obstructive sleep apnea | Q48550777 | ||
| Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats | Q48886060 | ||
| ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver | Q50336015 | ||
| Polygraphic study of the episodic diurnal and nocturnal (hypnic and respiratory) manifestations of the pickwick syndrome | Q51239571 | ||
| Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells | Q59487770 | ||
| High Hepatic SCD1 Activity Is Associated with Low Liver Fat Content in Healthy Subjects under a Lipogenic Diet | Q61862442 | ||
| Control of fatty acid metabolism in ischemic and hypoxic hearts | Q67342168 | ||
| Effect of palmitate concentration on the relative contributions of the beta-oxidation pathway and citric acid cycle to total O2 consumption of isolated rat hepatocytes | Q70565846 | ||
| Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats | Q70618933 | ||
| Effect of acute and chronic ethanol consumption on hepatic tissue oxygen tension in rats | Q71237493 | ||
| On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction | Q71357736 | ||
| Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo | Q73208990 | ||
| Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene | Q79074189 | ||
| The role of hypoxia in the pathogenesis of alcoholic liver disease | Q80133686 | ||
| Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketones | Q33577124 | ||
| Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance | Q33604466 | ||
| Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis | Q33685179 | ||
| Oxygen: modulator of metabolic zonation and disease of the liver | Q33828310 | ||
| Macrophages: master regulators of inflammation and fibrosis | Q34076279 | ||
| Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. | Q34091273 | ||
| Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus | Q34139027 | ||
| Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells | Q34349638 | ||
| Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation | Q34512108 | ||
| Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism | Q34598057 | ||
| Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes | Q34835012 | ||
| Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis | Q34996476 | ||
| Fatty liver is associated with transcriptional downregulation of stearoyl-CoA desaturase and impaired protein dimerization. | Q35010425 | ||
| Xanthine oxidase mediates hypoxia-inducible factor-2α degradation by intermittent hypoxia | Q35016826 | ||
| Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes | Q35034353 | ||
| Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo | Q35065823 | ||
| Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation | Q35072131 | ||
| HIF hydroxylation and the mammalian oxygen-sensing pathway | Q35086143 | ||
| Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis | Q35131965 | ||
| Metabolic features of clear-cell renal cell carcinoma: mechanisms and clinical implications | Q35137857 | ||
| High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia | Q35216069 | ||
| Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice | Q35227126 | ||
| Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism | Q35529754 | ||
| Human fatty liver disease: old questions and new insights | Q35588477 | ||
| Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity | Q35702905 | ||
| Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells | Q35855600 | ||
| Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice | Q35913174 | ||
| Lipid accumulation of hypoxic tissue culture cells | Q36077757 | ||
| Stearoyl-CoA desaturase as a new drug target for obesity treatment. | Q36100781 | ||
| Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice | Q36243894 | ||
| Integration of oxygen signaling at the consensus HRE. | Q36290265 | ||
| Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice | Q36479005 | ||
| Alcohol and lipid metabolism | Q36588210 | ||
| Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes. | Q36596160 | ||
| The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells | Q43495714 | ||
| Obstructive sleep apnea is independently associated with insulin resistance. | Q43903080 | ||
| HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation | Q36907933 | ||
| Hypoxia-induced signaling in the cardiovascular system | Q36938391 | ||
| Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo | Q37060555 | ||
| Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities. | Q37061642 | ||
| Mitochondrial complex III regulates hypoxic activation of HIF. | Q37064874 | ||
| Obstructive sleep apnea, insulin resistance, and steatohepatitis in severe obesity | Q37077790 | ||
| Molecular mechanisms of alcoholic fatty liver | Q37078754 | ||
| High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo | Q37087840 | ||
| SREBPs: the crossroads of physiological and pathological lipid homeostasis | Q37091373 | ||
| Effect of Telmisartan or Losartan for Treatment of Nonalcoholic Fatty Liver Disease: Fatty Liver Protection Trial by Telmisartan or Losartan Study (FANTASY). | Q37127287 | ||
| Reduced liver fibrosis in hypoxia-inducible factor-1alpha-deficient mice | Q37138759 | ||
| NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha | Q37158836 | ||
| Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR. | Q37228613 | ||
| Insulin resistance, inflammation, and non-alcoholic fatty liver disease | Q37301920 | ||
| Hypoxia-inducible factor 2 regulates hepatic lipid metabolism | Q37302297 | ||
| Oxygen sensors at the crossroad of metabolism | Q37360663 | ||
| Regulation of oxygen homeostasis by hypoxia-inducible factor 1. | Q37443475 | ||
| Recent insights into fatty liver, metabolic dyslipidaemia and their links to insulin resistance | Q37768004 | ||
| Hypoxia: A Link between Fibrogenesis, Angiogenesis, and Carcinogenesis in Liver Disease | Q37776185 | ||
| Regulation of Nutrient Metabolism and Inflammation | Q37791883 | ||
| Hypoxia and inflammation | Q37842498 | ||
| Hypoxia and hypoxia inducible factors: diverse roles in liver diseases | Q37961603 | ||
| Hypoxia, hypoxia-inducible factors and fibrogenesis in chronic liver diseases | Q38133457 | ||
| Intermittent hypoxia induces hyperlipidemia in lean mice. | Q38321740 | ||
| Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice | Q38323357 | ||
| HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells | Q39722018 | ||
| Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction. | Q39760512 | ||
| Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1. | Q40012178 | ||
| Incomplete compensation of enhanced hepatic oxygen consumption in rats with alcoholic centrilobular liver necrosis | Q41349177 | ||
| Cytochrome P-4502E1: its physiological and pathological role | Q41441345 | ||
| Is hypoxia involved in the mechanism of alcohol-induced liver injury? | Q41595630 | ||
| Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death. | Q41765603 | ||
| Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice. | Q41988947 | ||
| Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity | Q42281596 | ||
| A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo | Q42614205 | ||
| A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance | Q42812210 | ||
| Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia | Q42817965 | ||
| Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan | Q42917230 | ||
| Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases | Q42935424 | ||
| Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, improves hepatic microcirculatory patency and oxygen availability in a high-fat-diet-induced fatty liver in mice | Q43142149 | ||
| Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity | Q43200840 | ||
| Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN. | Q43260810 | ||
| P433 | issue | 41 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 15087-15097 | |
| P577 | publication date | 2014-11-01 | |
| P1433 | published in | World Journal of Gastroenterology | Q15708885 |
| P1476 | title | Hypoxia and fatty liver | |
| P478 | volume | 20 |
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