Dual renin-angiotensin-aldosterone blockade: promises and pitfalls

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Dual renin-angiotensin-aldosterone blockade: promises and pitfalls is …
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P6179Dimensions Publication ID1004527104
P356DOI10.1007/S11906-014-0511-3
P698PubMed publication ID25447989

P2093author name stringGeorge S Chrysant
Steven G Chrysant
P2860cites work2009 focused update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaborationQ22306346
Standards of medical care in diabetes--2012Q24632533
Telmisartan, ramipril, or both in patients at high risk for vascular eventsQ33156143
Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers for ischemic heart diseaseQ33158176
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failureQ34106793
Proinflammatory actions of angiotensins.Q34244757
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trialQ34246891
Vascular remodeling: the role of angiotensin-converting enzyme inhibitorsQ34458849
ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with theQ34640762
Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertensionQ36088984
The role of renin-angiotensin-aldosterone system in the progression of chronic kidney diseaseQ36335340
The pleiotropic effects of angiotensin receptor blockersQ36440956
Angiotensin-converting enzyme inhibitors in coronary artery disease and preserved left ventricular systolic function: a systematic review and meta-analysis of randomized controlled trialsQ36456291
Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trialsQ36564282
Efficacy and safety of dual blockade of the renin-angiotensin system: meta-analysis of randomised trialsQ36567554
Bayesian meta-analysis of tissue angiotensin-converting enzyme inhibitors for reduction of adverse cardiovascular events in patients with diabetes mellitus and preserved left ventricular functionQ37104532
Safety and tolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: a systematic review and meta-analysiQ37125268
Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) studyQ37368689
Effects of dual blockade of the renin-angiotensin system on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy and hypertension in the ORIENT: a post-hoc analysis (ORIENT-Hypertension).Q37369476
Pleiotropic effects of drugs inhibiting the renin-angiotensin-aldosterone systemQ37387558
The treatment of cardiovascular disease continuum: focus on prevention and RAS blockadeQ37692452
Current status of dual Renin Angiotensin aldosterone system blockade for the treatment of cardiovascular diseasesQ37704702
The antihypertensive effectiveness and safety of dual RAAS blockade with aliskiren and valsartanQ37751926
Renin Angiotensin Aldosterone System Blockade: Little to No Rationale for ACE Inhibitor and ARB CombinationsQ37824165
Combination inhibition of the renin-angiotensin system: is more better?Q37883908
Combinations of renin-angiotensin-aldosterone system antagonists: true advantages?Q37979298
Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trialQ38454911
Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertensionQ38497893
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or bothQ39669015
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular diseaseQ39895582
Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failureQ43266277
Efficacy of candesartan cilexetil as add-on therapy in hypertensive patients uncontrolled on background therapy: a clinical experience trial. ACTION Study InvestigatorsQ43644352
Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trialQ44280775
Dual blockade of the renin-angiotensin system versus maximal recommended dose of ACE inhibition in diabetic nephropathyQ44390528
Renoprotective effects of adding angiotensin II receptor blocker to maximal recommended doses of ACE inhibitor in diabetic nephropathy: a randomized double-blind crossover trialQ44526964
Hyperkalemia and renal function during monotherapy and dual renin-angiotensin blockade in the community settingQ44581514
Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failureQ44824452
Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trialQ45027934
Antihypertensive efficacy of candesartan-lisinopril in combination vs. up-titration of lisinopril: the AMAZE trialsQ45057353
Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruptionQ45173412
Long-term dual blockade with candesartan and lisinopril in hypertensive patients with diabetes: the CALM II study.Q45242324
Effect of dual blockade of the renin-angiotensin system on the progression of type 2 diabetic nephropathy: a randomized trial.Q46016219
Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophyQ46157336
Renin inhibition improves cardiac function and remodeling after myocardial infarction independent of blood pressureQ46291373
Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial.Q46426098
The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety studyQ46579672
Synergistic effects of ACE inhibition and Ang II antagonism on blood pressure, cardiac weight, and renin in spontaneously hypertensive ratsQ47298474
Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study InvestigatorsQ48118604
Tissue angiotensin-converting enzyme inhibitors for the prevention of cardiovascular disease in patients with diabetes mellitus without left ventricular systolic dysfunction or clinical evidence of heart failure: a pooled meta-analysis of randomizedQ50653081
Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide.Q55042793
Angiotensin-Converting Enzyme Inhibitors in Patients With Coronary Artery Disease and Absence of Heart Failure or Left Ventricular Systolic DysfunctionQ57243489
Effect of the direct renin inhibitor aliskiren on left ventricular remodelling following myocardial infarction with systolic dysfunctionQ57396225
Blood pressure-dependent and independent effects of agents that inhibit the renin–angiotensin systemQ57583262
Pathophysiology of Progressive NephropathiesQ57703963
Dual RAAS suppression: recent developments and implications in light of the ALTITUDE studyQ61455603
Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: Results of the IMPROVE trialQ61455820
Effects of benazepril and hydrochlorothiazide, given alone and in low- and high-dose combinations, on blood pressure in patients with hypertensionQ70838730
Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartanQ79470523
Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta-analysisQ79969450
Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trialQ80688403
Tissue ACE inhibitors for secondary prevention of cardiovascular disease in patients with preserved left ventricular function: a pooled meta-analysis of randomized placebo-controlled trialsQ81310848
P433issue1
P304page(s)511
P577publication date2015-01-01
P1433published inCurrent Hypertension ReportsQ15746362
P1476titleDual renin-angiotensin-aldosterone blockade: promises and pitfalls
P478volume17

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Q37347190New agents modulating the renin-angiotensin-aldosterone system-Will there be a new therapeutic option?cites workP2860

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