Specific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells

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Specific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JNR.10252
P698PubMed publication ID12111836

P2093author name stringJohn M Wells
Richard E Fine
M David Ullman
Patricia B Eisenhauer
Kelly J Conn
Catherine McKeon-O'Malley
Wen-Wu Gao
P2860cites workEffect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in goldfish brainQ48858048
Effects of MPTP on the fine structure of neurons in substantia nigra of dogsQ49051349
1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particlesQ68474033
Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ionQ68818368
Expression of dopamine transporter at the tips of growing neurites of PC12 cellsQ71444368
CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteinsQ22010670
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesisQ22242250
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activityQ24290192
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of ParkinQ24291412
DNA damage-inducible transcripts in mammalian cellsQ24644830
Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesisQ28138279
Emerging roles of caspase-3 in apoptosisQ28141417
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcriptionQ28287446
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulumQ28509611
The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nucleiQ28568895
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control elementQ28570085
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox stateQ28572472
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controlsQ29547730
Chronic systemic pesticide exposure reproduces features of Parkinson's diseaseQ29614763
MPP+ induced apoptotic cell death in SH-SY5Y neuroblastoma cells: an electron microscope studyQ30470518
Role of mitochondria in Parkinson diseaseQ33737269
Does neuronal loss in Parkinson's disease involve programmed cell death?Q34312949
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).Q36561426
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicityQ37683630
CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding elementQ39607669
Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanismsQ40796296
Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cellsQ41157654
Oxidative stress and the pathogenesis of Parkinson's diseaseQ41262986
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonismQ42216349
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.Q42801637
CHOP/GADD153 gene expression response to cellular stresses inhibited by prior exposure to ultraviolet light wavelength band C (UVC). Inhibitory sequence mediating the UVC response localized to exon 1.Q42835434
Decreased expression of the NADH:ubiquinone oxidoreductase (complex I) subunit 4 in 1-methyl-4-phenylpyridinium -treated human neuroblastoma SH-SY5Y cellsQ43640148
Basal lipid peroxidation in substantia nigra is increased in Parkinson's diseaseQ44808814
The acute histopathology of MPTP in the mouse CNS.Q46607010
Neuropathological study on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of the crab-eating monkeyQ48139739
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.Q48310314
P433issue6
P304page(s)755-760
P577publication date2002-06-01
P1433published inJournal of Neuroscience ResearchQ6295654
P1476titleSpecific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells
P478volume68

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cites work (P2860)
Q30310797Dependence on electron transport chain function and intracellular signaling of genomic responses in SH-SY5Y cells to the mitochondrial neurotoxin MPP+
Q38757158Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation
Q30310945Functional genomics and proteomics in control of breathing
Q39448529Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson's disease
Q48485896Intranigral dopamine toxicity and alpha-synuclein response in rats
Q30312031MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways
Q47648929Manganese- and 1-methyl-4-phenylpyridinium-induced neurotoxicity display differences in morphological, electrophysiological and genome-wide alterations: implications for idiopathic Parkinson's disease
Q28573057Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease
Q34263323Neurotoxin-induced pathway perturbation in human neuroblastoma SH-EP cells
Q40025713Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism.
Q24302012The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals
Q38024534The Parkinson's disease-related genes act in mitochondrial homeostasis
Q38347492cDNA microarray analysis of changes in gene expression associated with MPP+ toxicity in SH-SY5Y cells

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