Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3.

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Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.NEO.7900207
P932PMC publication ID1503316
P698PubMed publication ID11922392

P2093author name stringRaymond B Nagle
Thirupandiyur S Udayakumar
George Timothy Bowden
Mimi Suzanne Stratton
P2860cites workA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1Q24310428
Receptor specificity of the fibroblast growth factor familyQ24320178
Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinaseQ24598122
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylationQ24644334
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomasQ28116420
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cellsQ28146127
Structural and functional diversity in the FGF receptor multigene familyQ28265126
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylationQ28288257
Interleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaPQ28344474
A synthetic inhibitor of the mitogen-activated protein kinase cascadeQ28367955
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblastsQ28609143
Requirement of serine phosphorylation for formation of STAT-promoter complexesQ28637366
The mitogen-activated protein kinase signal transduction pathwayQ29620226
Transmodulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes.Q31942383
Serine phosphorylation of STATsQ33941422
Complexity of FGF receptors: genetic basis for structural diversity and functional specificityQ35595596
Deciphering the MAP kinase pathwayQ36719391
Extracellular signal-regulated kinases: ERKs in progressQ36746413
Control of protein exit from the endoplasmic reticulumQ38737565
Protein oligomerization in the endoplasmic reticulumQ38737584
MAP kinase kinase kinase, MAP kinase kinase and MAP kinaseQ40757575
Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factorsQ40833644
Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cellsQ40906010
Matrilysin: an epithelial matrix metalloproteinase with potentially novel functionsQ41053282
Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysisQ41360988
Prostate tumor cell invasion: a comparison of orthotopic and ectopic models.Q41587083
The heparan sulfate-fibroblast growth factor family: diversity of structure and function.Q41680432
Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 elementQ42440746
Extracellular signal-regulated protein kinase (ERK)-dependent and ERK-independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokinesQ42994196
Fibroblast growth factor-2 and -9 regulate proliferation and production of matrix metalloproteinases in human gliomas.Q48456076
bFGF and LIF signaling activates STAT3 in proliferating myoblastsQ50113529
Structural and Functional Diversity in the FGf Receptor Multigene FamilyQ55919452
Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth FactorQ58197226
Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomasQ67863004
Expression of metalloproteinase genes in human prostate cancerQ67914534
Endogenous basic fibroblast growth factor-dependent induction of collagenase and interleukin-6 in tumor necrosis factor-treated human microvascular endothelial cellsQ68257280
Effect of growth factors on collagen metabolism in cultured human heart fibroblastsQ68266203
In vitro changes in plasma membrane heparan sulfate proteoglycans and in perlecan expression participate in the regulation of fibroblast growth factor 2 mitogenic activityQ70890126
Matrilysin expression in human prostate carcinomaQ70900890
Stimulation of gelatinase B and tissue inhibitors of metalloproteinase (TIMP) production in co-culture of human osteosarcoma cells and human fibroblasts: gelatinase B production was stimulated via up-regulation of fibroblast growth factor (FGF) receQ71019291
Biosynthesis and secretion of laminin and S-laminin by human prostate carcinoma cell linesQ72072337
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesisQ72145804
Mitogen-activated protein kinases mediate matrix metalloproteinase-9 expression in vascular smooth muscle cellsQ73295316
Basic fibroblast growth factor regulates matrix metalloproteinases production and in vitro invasiveness in human bladder cancer cell linesQ73330012
PSA thresholds for prostate cancer detectionQ73673555
[Localization and expression of matrix metalloproteinase-7 in human prostate]Q73920159
Independent role of p38 and ERK1/2 mitogen-activated kinases in the upregulation of matrix metalloproteinase-1Q74060513
Emerging roles for proteinases in cancerQ77755681
Signal transduction by fibroblast growth factor receptorsQ78171822
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)60-67
P577publication date2002-01-01
P1433published inNeoplasiaQ2962042
P1476titleFibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3.
P478volume4

Reverse relations

cites work (P2860)
Q509645103D-spheroids: What can they tell us about pancreatic ductal adenocarcinoma cell phenotype?
Q35230410Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251.
Q46799876Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinases
Q48645834Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells
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Q35144719Dimerumic acid inhibits SW620 cell invasion by attenuating H₂O₂-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner.
Q40301635Dobesilate inhibits the activation of signal transducer and activator of transcription 3, and the expression of cyclin D1 and bcl-XL in glioma cells.
Q36180363Enhanced anti-apoptosis and gut epithelium protection function of acidic fibroblast growth factor after cancelling of its mitogenic activity
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Q34360616Human prostate cancer risk factors
Q53610905Matrix metalloproteinase-7 and epidermal growth factor receptor mediate hypoxia-induced extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase activation and subsequent proliferation in bladder smooth muscle cells.
Q30437556Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment
Q24802614Mitogen Activated Protein kinase signal transduction pathways in the prostate
Q33710074OSU-A9 inhibits pancreatic cancer cell lines by modulating p38-JAK-STAT3 signaling
Q79075846Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression
Q112653326Retracted Article: Gm5820, an antisense RNA of FGF1, suppresses FGF1 expression at the posttranscriptional level to inactivate the ERK/STAT3 pathway and alleviates neuropathic pain in mice
Q42847300Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction
Q39715263Signal transducers and activators of transcription-3 binding to the fibroblast growth factor receptor is activated by receptor amplification.
Q34786695Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Q37512303The role of fibroblast growth factors in tumor growth

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