scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.275.3.2147 |
P698 | PubMed publication ID | 10636920 |
P2093 | author name string | R A Bradshaw | |
Y Y Wu | |||
P2860 | cites work | Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6 | Q24297617 |
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis | Q24316448 | ||
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway | Q24531184 | ||
Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology | Q24564233 | ||
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation | Q24644334 | ||
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality | Q24685515 | ||
High-efficiency transformation of mammalian cells by plasmid DNA | Q27860469 | ||
Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860628 | ||
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
Jak2 is essential for signaling through a variety of cytokine receptors | Q28270987 | ||
Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction | Q28278147 | ||
Cytokines and the nervous system. I: Expression and recognition | Q28287817 | ||
Cytokines and the nervous system II: Actions and mechanisms of action | Q28301619 | ||
Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements | Q28571255 | ||
Requirement of serine phosphorylation for formation of STAT-promoter complexes | Q28637366 | ||
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 | Q28637521 | ||
Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation | Q28637692 | ||
STATs and gene regulation | Q29547796 | ||
Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease | Q29615967 | ||
Jaks and STATs: biological implications | Q29619657 | ||
STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase | Q34087183 | ||
Neuroendocrine-immune system interactions and autoimmunity | Q34300053 | ||
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses | Q34468309 | ||
Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. | Q34629986 | ||
Sympathetic neurons can produce and respond to interleukin 6 | Q35985223 | ||
Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds | Q36432406 | ||
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis | Q36571893 | ||
Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells | Q36728456 | ||
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro | Q37385294 | ||
Reflections on STAT3, STAT5, and STAT6 as fat STATs | Q37508544 | ||
STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line | Q37625031 | ||
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain | Q38354217 | ||
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase | Q39575287 | ||
Stat3 activation by Src induces specific gene regulation and is required for cell transformation | Q39583802 | ||
Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages | Q40016551 | ||
Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase | Q40023873 | ||
Cytokine receptor signalling | Q40416594 | ||
Neuronal differentiation factors/cytokines and synaptic plasticity | Q40873394 | ||
STATs: signal transducers and activators of transcription | Q40974978 | ||
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases | Q41075291 | ||
STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727. | Q41090036 | ||
The neurotrophins and CNTF: two families of collaborative neurotrophic factors | Q41132721 | ||
Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways | Q41150318 | ||
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. | Q41153893 | ||
Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: modulation by tumor necrosis factor alpha (TNF-alpha). | Q41240165 | ||
PC12-E2 cells: a stable variant with altered responses to growth factor stimulation | Q41306757 | ||
CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons | Q41449903 | ||
Interleukin 6 and its receptor: ten years later | Q41722189 | ||
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor | Q41978360 | ||
Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6. | Q42628720 | ||
Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains | Q45227108 | ||
Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line | Q46485002 | ||
Synergistic induction of neurite outgrowth by nerve growth factor or epidermal growth factor and interleukin-6 in PC12 cells | Q46545637 | ||
STATs as activators of apoptosis | Q47721568 | ||
Increasing complexity of the Ras signaling pathway | Q47762067 | ||
Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death | Q48139177 | ||
Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin | Q48375261 | ||
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway | Q48617330 | ||
Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 | Q56690299 | ||
Not just another meeting: the coming of age of JAKs and STATs | Q56933132 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | interleukins | Q194908 |
P304 | page(s) | 2147-2156 | |
P577 | publication date | 2000-01-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells | |
P478 | volume | 275 |
Q43073859 | Activation of STAT3 by pituitary adenylate cyclase-activating polypeptide (PACAP) during PACAP-promoted neurite outgrowth of PC12 cells |
Q60594494 | Activation of Stat-3 as one of the early events in tobacco chewing-mediated oral carcinogenesis |
Q30650799 | An automated fluorescence based assay of neurite formation |
Q36713529 | An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis |
Q28582726 | An essential role of the Jak-2/STAT-3/cytosolic phospholipase A(2) axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motility |
Q28566936 | Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth |
Q35003859 | Chemical genetic screening approaches to neurobiology |
Q64904616 | Chemotherapy-Induced Peripheral Neuropathy and Changes in Cytoskeleton. |
Q33919760 | Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats |
Q44279253 | Cytosolic phospholipase A2 is an effector of Jak/STAT signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells |
Q39439940 | Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons |
Q35780674 | Effects of Reducing Suppressors of Cytokine Signaling-3 (SOCS3) Expression on Dendritic Outgrowth and Demyelination after Spinal Cord Injury |
Q44658021 | Expression of galectin‐3 in neuronally differentiating PC12 cells is regulated both via Ras/MAPK‐dependent and –independent signalling pathways |
Q38290665 | Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3. |
Q42836193 | Functional whole-genome analysis identifies Polo-like kinase 2 and poliovirus receptor as essential for neuronal differentiation upstream of the negative regulator alphaB-crystallin. |
Q34334392 | Impact of cell swelling on proliferative signal transduction in the liver |
Q38361170 | Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor. |
Q42798316 | Insulin induces epidermal growth factor (EGF) receptor clustering and potentiates EGF-stimulated DNA synthesis in swiss 3T3 cells: a mechanism for costimulation in mitogenic synergy |
Q37331339 | Interleukin-10 provides direct trophic support to neurons. |
Q28344474 | Interleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP |
Q42508217 | Interleukin-6 protects rat PC12 cells from serum deprivation or chemotherapeutic agents through the phosphatidylinositol 3-kinase and STAT3 pathways |
Q28571934 | Leukemia inhibitory factor receptor signaling negatively modulates nerve growth factor-induced neurite outgrowth in PC12 cells and sympathetic neurons |
Q36026076 | Mechanisms of action of antidepressants: from neurotransmitter systems to signaling pathways |
Q33955275 | Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth |
Q43746975 | Nerve growth factor uses Ras/ERK and phosphatidylinositol 3-kinase cascades to up-regulate the N-methyl-D-aspartate receptor 1 promoter |
Q48187789 | Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function |
Q40345587 | ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation. |
Q28115789 | Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation |
Q33969194 | Regulation of Id gene expression by type I insulin-like growth factor: roles of Stat3 and the tyrosine 950 residue of the receptor |
Q34746354 | Regulation of neurite outgrowth by G(i/o) signaling pathways |
Q36602612 | Role of the Go/i signaling network in the regulation of neurite outgrowth. |
Q45153426 | STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility |
Q47074089 | STAT3-dependent pathfinding and control of axonal branching and target selection |
Q36007499 | Suppression of activation of signal transducer and activator of transcription-5B signaling in the vessel wall reduces balloon injury-induced neointima formation |
Q40232250 | Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. |
Q46186932 | TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity |
Q37237506 | The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8. |
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