Activation of STAT3 by pituitary adenylate cyclase-activating polypeptide (PACAP) during PACAP-promoted neurite outgrowth of PC12 cells

scientific article published on 5 May 2010

Activation of STAT3 by pituitary adenylate cyclase-activating polypeptide (PACAP) during PACAP-promoted neurite outgrowth of PC12 cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1003043122
P356DOI10.1007/S12031-010-9376-3
P698PubMed publication ID20443077

P2093author name stringMasami Ishido
P2860cites workDicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivityQ45067542
PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathwayQ48295219
Multiple routes to astrocytic differentiation in the CNS.Q48455897
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Pituitary adenylyl cyclase-activating peptide stimulates extracellular signal-regulated kinase 1 or 2 (ERK1/2) activity in a Ras-independent, mitogen-activated protein Kinase/ERK kinase 1 or 2-dependent manner in PC12 cellsQ48638484
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Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cellsQ58328441
The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowthQ64972473
Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cellsQ69772725
The 38-amino-acid form of pituitary adenylate cyclase-activating polypeptide induces neurite outgrowth in PC12 cells that is dependent on protein kinase C and extracellular signal-regulated kinase but not on protein kinase A, nerve growth factor recQ77217477
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathwayQ24305237
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Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylationQ24632832
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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6Q28637521
Stats: transcriptional control and biological impactQ29547776
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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cellsQ29618480
Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions.Q33903904
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cellsQ33940377
The Stat family in cytokine signalingQ34180677
Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.Q34624638
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Pituitary adenylate cyclase-activating polypeptide is an autocrine inhibitor of mitosis in cultured cortical precursor cellsQ36085551
Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptorQ36408013
Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylationQ37467580
STAT3 as a downstream mediator of Trk signaling and functionsQ38314297
Interleukin-6 inhibits receptor activator of nuclear factor kappaB ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine727 phosphorylation of signal transducer and activator of transcription 3.Q39993181
Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancerQ40079462
A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress.Q40521156
cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6.Q40593822
Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cellsQ40906010
STATs: signal transducers and activators of transcriptionQ40974978
Transcriptome of pituitary adenylate cyclase-activating polypeptide-differentiated PC12 cellsQ42169838
PACAP stimulates dopamine neuronal activity in the medial basal hypothalamus and inhibits prolactinQ42455462
PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells.Q44816143
Bisphenol A causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivityQ44840517
P433issue3
P921main subjectneuriteQ1534415
P304page(s)349-358
P577publication date2010-05-05
P1433published inJournal of Molecular NeuroscienceQ15708870
P1476titleActivation of STAT3 by pituitary adenylate cyclase-activating polypeptide (PACAP) during PACAP-promoted neurite outgrowth of PC12 cells
P478volume42

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Q39568185Neurotrophic effects of leukemia inhibitory factor on neural cells derived from human embryonic stem cellscites workP2860