Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen

scientific article

Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M112215200
P698PubMed publication ID11823467

P2093author name stringLi Zhong
Changqing Zhao
Debra F Skafar
Janice A Schwartz
Sarah Deighton-Collins
P2860cites workHelix cappingQ24673351
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Molecular basis of agonism and antagonism in the oestrogen receptorQ27746278
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifenQ27766417
The steroid and thyroid hormone receptor superfamilyQ27861095
Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonistsQ33888199
State of the arg: protein methylation at arginine comes of age.Q34084396
The PROSITE database, its status in 1997.Q34622236
Positive cooperativity of the estrogen receptorQ35460526
Unique protein determinants of the subtype-selective ligand responses of the estrogen receptors (ERalpha and ERbeta ) at AP-1 sitesQ38307076
An assessment of the role of domain F and PEST sequences in estrogen receptor half-life and bioactivityQ38313711
Estrogen receptor domains E and F: role in dimerization and interaction with coactivator RIP-140.Q38328418
Sequence determinants of the capping box, a stabilizing motif at the N-termini of alpha-helicesQ41825033
Phosphorylation of serine-46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure.Q41959152
Function of estrogen receptor tyrosine 537 in hormone binding, DNA binding, and transactivation.Q42614325
The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonistsQ42826611
Conformational preferences of amino acids in globular proteinsQ44870543
GOR method for predicting protein secondary structure from amino acid sequence.Q52319038
An algorithm for protein secondary structure prediction based on class prediction.Q52591620
Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis.Q54160126
Influence of N-cap mutations on the structure and stability of Escherichia coli HPr.Q54581092
Structural consequences of histidine phosphorylation: NMR characterization of the phosphohistidine form of histidine-containing protein from Bacillus subtilis and Escherichia coli.Q54622046
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)13202-13209
P577publication date2002-01-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleMutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen
P478volume277

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