review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Mesut Muyan | |
Gamze Ayaz | |||
Pelin Yaşar | |||
Gizem Güpür | |||
Sırma Damla User | |||
P2860 | cites work | Molecular determinants of the estrogen receptor-coactivator interface | Q22009427 |
Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elements | Q22253217 | ||
Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2. | Q24290966 | ||
Characterization of the physical interaction between estrogen receptor alpha and JUN proteins | Q24291491 | ||
Cloning and characterization of human estrogen receptor beta isoforms | Q24309303 | ||
Mitochondrial localization of estrogen receptor beta | Q24317220 | ||
Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor ofestrogen action in human | Q24317428 | ||
ER beta: identification and characterization of a novel human estrogen receptor | Q24317610 | ||
Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways | Q24562820 | ||
Genomic organization of the human oestrogen receptor gene | Q24564158 | ||
The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties | Q24567487 | ||
Cloning of a novel receptor expressed in rat prostate and ovary | Q24607949 | ||
Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding | Q24647300 | ||
Estrogenic control of mitochondrial function and biogenesis | Q24651145 | ||
Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling | Q24673409 | ||
Structural and functional domains of the estrogen receptor | Q68760010 | ||
Functional domains of the human estrogen receptor | Q69466265 | ||
Expression of estrogen receptor alpha exon 5 and 7 deletion variant in human breast cancers | Q73072971 | ||
The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens | Q73222352 | ||
Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system | Q73311903 | ||
Estrogen receptors alpha and beta form heterodimers on DNA | Q73555536 | ||
Functional differences between the amino-terminal domains of estrogen receptors alpha and beta | Q74206606 | ||
Interaction of estrogen receptors alpha and beta with estrogen response elements | Q74284425 | ||
Transcription activation by the human estrogen receptor subtype beta (ER beta) studied with ER beta and ER alpha receptor chimeras | Q77484181 | ||
A comparison of transcriptional activation by ER alpha and ER beta | Q78036257 | ||
Putative functional characteristics of human estrogen receptor-beta isoforms | Q78966420 | ||
Mitochondrial estrogen receptors--new insights into specific functions | Q79836225 | ||
AP-2 regulates the transcription of estrogen receptor (ER)-beta by acting through a methylation hotspot of the 0N promoter in prostate cancer cells | Q80382759 | ||
What's new in estrogen receptor action in the female reproductive tract | Q26772956 | ||
A bi-faceted role of estrogen receptor β in breast cancer | Q27025419 | ||
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist | Q27619550 | ||
Structural insights into corepressor recognition by antagonist-bound estrogen receptors | Q27643750 | ||
The 2.0 Å crystal structure of the ERα ligand-binding domain complexed with lasofoxifene | Q27644597 | ||
The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation | Q27730214 | ||
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements | Q27731441 | ||
Molecular basis of agonism and antagonism in the oestrogen receptor | Q27746278 | ||
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen | Q27766417 | ||
The steroid and thyroid hormone receptor superfamily | Q27861095 | ||
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase | Q28144544 | ||
Minireview: genomic organization of the human ERalpha gene promoter region | Q28208469 | ||
Estrogen production and action | Q28213624 | ||
Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha | Q28250835 | ||
Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern | Q28256533 | ||
The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro | Q28262532 | ||
Estrogen biology: new insights into GPER function and clinical opportunities | Q28307726 | ||
Response element sequence modulates estrogen receptor alpha and beta affinity and activity | Q28567336 | ||
Regulation of estrogen receptor α N-terminus conformation and function by peptidyl prolyl isomerase Pin1 | Q28569016 | ||
The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties | Q28909277 | ||
Nuclear receptor coregulators: cellular and molecular biology | Q29547588 | ||
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription | Q29547846 | ||
Importing mitochondrial proteins: machineries and mechanisms | Q29616477 | ||
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter | Q29616537 | ||
The human estrogen receptor has two independent nonacidic transcriptional activation functions | Q29617089 | ||
Estrogen receptors: how do they signal and what are their targets | Q29617958 | ||
AP-1 function and regulation | Q29618422 | ||
Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. | Q30329800 | ||
Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics | Q30418832 | ||
Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing | Q30438057 | ||
Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis | Q30444265 | ||
The ligand-mediated nuclear mobility and interaction with estrogen-responsive elements of estrogen receptors are subtype specific | Q30540362 | ||
Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions. | Q30565938 | ||
Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis | Q31065757 | ||
Whole-genome cartography of estrogen receptor alpha binding sites | Q33286418 | ||
Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection | Q33576510 | ||
Direct interactions with G α i and G βγ mediate nongenomic signaling by estrogen receptor α . | Q52578149 | ||
Estrogen receptor beta in breast cancer | Q57129171 | ||
Identification of Regions within the F Domain of the Human Estrogen Receptor α that Are Important for Modulating Transactivation and Protein-Protein Interactions | Q57266627 | ||
Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells | Q57849120 | ||
Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element | Q59070120 | ||
Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements | Q60956082 | ||
Variant human breast tumor estrogen receptor with constitutive transcriptional activity | Q68183370 | ||
Estrogen receptor-beta: recent lessons from in vivo studies | Q36429940 | ||
Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. | Q36487632 | ||
The genome landscape of ERalpha- and ERbeta-binding DNA regions | Q36497435 | ||
Estrogen hormone physiology: reproductive findings from estrogen receptor mutant mice | Q36649065 | ||
Plasma membrane estrogen receptors | Q36660250 | ||
Hormone-dependent nuclear export of estradiol receptor and DNA synthesis in breast cancer cells | Q36790500 | ||
New insights into the classical and non-classical actions of estrogen: evidence from estrogen receptor knock-out and knock-in mice | Q36925064 | ||
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways | Q36970038 | ||
Mitochondrial nuclear receptors and transcription factors: who's minding the cell? | Q37015652 | ||
Membrane association of estrogen receptor alpha and beta influences 17beta-estradiol-mediated cancer cell proliferation | Q37060635 | ||
Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse | Q37081899 | ||
Estrogen receptor α L543A,L544A mutation changes antagonists to agonists, correlating with the ligand binding domain dimerization associated with DNA binding activity | Q37175135 | ||
Estrogen actions on mitochondria--physiological and pathological implications | Q37197561 | ||
Phosphorylation: a fundamental regulator of steroid receptor action | Q37198642 | ||
Nuclear receptor coactivators: essential players for steroid hormone action in the brain and in behaviour. | Q37228583 | ||
Bidirectional Crosstalk between the Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Signaling Pathways in Breast Cancer: Molecular Basis and Clinical Implications | Q37255088 | ||
Marking time: the dynamic role of chromatin and covalent modification in transcription | Q37274848 | ||
Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications | Q37348421 | ||
Understanding nuclear receptor form and function using structural biology | Q37411882 | ||
Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer. | Q37430548 | ||
Transcriptional complexes engaged by apo-estrogen receptor-alpha isoforms have divergent outcomes | Q37524499 | ||
Structural and functional relationships of the steroid hormone receptors' N-terminal transactivation domain | Q37576700 | ||
Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover | Q37599824 | ||
Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility | Q37652763 | ||
Cracking the estrogen receptor's posttranslational code in breast tumors | Q37890710 | ||
The different roles of ER subtypes in cancer biology and therapy | Q37903655 | ||
Advances in the understanding of the structure and function of ER-α36,a novel variant of human estrogen receptor-alpha. | Q37925902 | ||
Estrogen carcinogenesis in breast cancer | Q37926105 | ||
Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy. | Q38186042 | ||
Identification and characterization of a functionally distinct form of human estrogen receptor beta | Q38291088 | ||
Mutations targeted to a predicted helix in the extreme carboxyl-terminal region of the human estrogen receptor-alpha alter its response to estradiol and 4-hydroxytamoxifen | Q38292426 | ||
Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. | Q38328627 | ||
Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors | Q38331026 | ||
Distinct classes of transcriptional activating domains function by different mechanisms | Q38339126 | ||
Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor | Q38346347 | ||
Structure of a biologically active estrogen receptor-coactivator complex on DNA. | Q35205425 | ||
Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses. | Q35338975 | ||
Estrogen receptor corepressors -- a role in human breast cancer? | Q35624506 | ||
Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators | Q35752145 | ||
Post-translational modifications of nuclear receptors and human disease | Q35842790 | ||
Estrogen receptor-beta and breast cancer: translating biology into clinical practice | Q35973424 | ||
Estrogen receptor mutations in human disease | Q35975453 | ||
Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological implications | Q36260069 | ||
Sp transcription factor family and its role in cancer | Q36279169 | ||
S-palmitoylation modulates estrogen receptor alpha localization and functions. | Q36308079 | ||
Nuclear control of respiratory gene expression in mammalian cells | Q36331586 | ||
Molecular basis of therapeutic strategies for breast cancer | Q36352235 | ||
Estrogen Receptor-α Promotes Breast Cancer Cell Motility and Invasion via Focal Adhesion Kinase and N-WASP | Q33637191 | ||
Minireview: Estrogen receptor-beta: mechanistic insights from recent studies | Q33637261 | ||
DNA binding by estrogen receptor-alpha is essential for the transcriptional response to estrogen in the liver and the uterus | Q33642080 | ||
Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor | Q33668322 | ||
Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse | Q33701376 | ||
Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1. | Q33756323 | ||
Membrane-localized estrogen receptor α is required for normal organ development and function | Q33772814 | ||
The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors | Q33881484 | ||
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation | Q33911291 | ||
Extranuclear estrogen receptor's roles in physiology: lessons from mouse models | Q33913090 | ||
Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor alpha-beta heterodimeric complex | Q33957429 | ||
A structural biologist's view of the oestrogen receptor. | Q34132640 | ||
Estrogen receptor pathways to AP-1. | Q34132667 | ||
Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions | Q34247103 | ||
DNA methylation in breast cancer | Q34304102 | ||
Estrogen receptor interaction with estrogen response elements | Q34307898 | ||
The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer | Q34311300 | ||
The multifaceted mechanisms of estradiol and estrogen receptor signaling. | Q34311547 | ||
Estrogen receptor and breast cancer | Q34372818 | ||
Estrogen Signaling via Estrogen Receptor β | Q34400742 | ||
What have we learned about GPER function in physiology and disease from knockout mice? | Q34485765 | ||
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway | Q34493228 | ||
Production and actions of estrogens | Q34513002 | ||
Functional estrogen receptors in the mitochondria of breast cancer cells | Q34559531 | ||
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer | Q34692670 | ||
Human estrogen receptor-alpha: regulation by synthesis, modification and degradation. | Q34712217 | ||
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions | Q34727705 | ||
Estrogen receptor mediates a distinct mitochondrial unfolded protein response | Q34808600 | ||
Structural insights into Resveratrol's antagonist and partial agonist actions on estrogen receptor alpha | Q35026250 | ||
Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions | Q35038193 | ||
Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor | Q35055471 | ||
Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing | Q35164579 | ||
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation | Q35189958 | ||
Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators | Q35202616 | ||
The cis decoy against the estrogen response element suppresses breast cancer cells via target disrupting c-fos not mitogen-activated protein kinase activity | Q38355056 | ||
Proximal events in signaling by plasma membrane estrogen receptors | Q38361235 | ||
Estrogen receptor alpha-36 (ER-α36): A new player in human breast cancer | Q38445141 | ||
Estrogen receptors similarly mediate the effects of 17β-estradiol on cellular responses but differ in their potencies | Q39633198 | ||
Binding of estrogen receptor alpha/beta heterodimers to chromatin in MCF-7 cells | Q39859307 | ||
Genomic responses from the estrogen-responsive element-dependent signaling pathway mediated by estrogen receptor alpha are required to elicit cellular alterations | Q39868294 | ||
Gene expression profiling reveals that the regulation of estrogen-responsive element-independent genes by 17 beta-estradiol-estrogen receptor beta is uncoupled from the induction of phenotypic changes in cell models | Q39988677 | ||
Transient cyclical methylation of promoter DNA. | Q40005345 | ||
Cyclical DNA methylation of a transcriptionally active promoter | Q40005351 | ||
Estrogen receptor DNA binding is not required for estrogen-induced breast cell growth | Q40083482 | ||
Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. | Q40151982 | ||
Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer | Q40198718 | ||
Epigenetic changes in estrogen receptor beta gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence | Q40207630 | ||
Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells | Q40261207 | ||
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. | Q40263593 | ||
Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66. | Q40373157 | ||
The nuclear hormone receptor gene superfamily | Q40436848 | ||
The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. | Q40448463 | ||
Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors alpha and beta to human mitochondrial DNA estrogen response elements | Q40515616 | ||
Targeting estrogen responsive elements (EREs): design of potent transactivators for ERE-containing genes | Q40558517 | ||
Expression of estrogen receptor beta isoforms in normal breast epithelial cells and breast cancer: regulation by methylation | Q40623346 | ||
A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor | Q40640074 | ||
Down but not out? A novel protein isoform of the estrogen receptor alpha is expressed in the estrogen receptor alpha knockout mouse. | Q40686513 | ||
Differences in the abilities of estrogen receptors to integrate activation functions are critical for subtype-specific transcriptional responses | Q40714908 | ||
The dynamic structure of the estrogen receptor | Q40720904 | ||
The effects of estrogen-responsive element- and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ER alpha and ER beta | Q40741473 | ||
ERalpha gene expression in human primary osteoblasts: evidence for the expression of two receptor proteins | Q40765356 | ||
Estrogen receptor binding to DNA is not required for its activity through the nonclassical AP1 pathway | Q40817246 | ||
On the mechanism of DNA binding by nuclear hormone receptors: a structural and functional perspective | Q40879984 | ||
The N-terminal DNA-binding 'zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity | Q41092852 | ||
Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue | Q41468779 | ||
Steroid signaling activation and intracellular localization of sex steroid receptors. | Q41497140 | ||
The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions | Q41695662 | ||
Cloning and characterization of human estrogen receptor beta promoter | Q41758375 | ||
A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses | Q41890192 | ||
What are comparative studies telling us about the mechanism of ERbeta action in the ERE-dependent E2 signaling pathway? | Q41952201 | ||
Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis | Q42505370 | ||
The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists | Q42826611 | ||
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent | Q43516734 | ||
Subcellular distribution of native estrogen receptor alpha and beta isoforms in rabbit uterus and ovary | Q43704443 | ||
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues | Q43799655 | ||
Mutations in the estrogen receptor DNA-binding domain discriminate between the classical mechanism of action and cross-talk with Stat5b and activating protein 1 (AP-1). | Q44201649 | ||
Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate | Q44232745 | ||
Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells | Q44294745 | ||
The naturally occurring variant of estrogen receptor (ER) ERDeltaE7 suppresses estrogen-dependent transcriptional activation by both wild-type ERalpha and ERbeta | Q44480616 | ||
Synergism between genomic and non genomic estrogen action mechanisms | Q44488593 | ||
Human estrogen receptor beta 548 is not a common variant in three distinct populations | Q44514613 | ||
S-palmitoylation modulates human estrogen receptor-alpha functions | Q44807022 | ||
Plasma membrane estrogen receptors exist and functions as dimers | Q44962115 | ||
Estrogen receptor activation function 1 works by binding p160 coactivator proteins | Q46064993 | ||
A conserved mechanism for steroid receptor translocation to the plasma membrane | Q46081038 | ||
Binding of estrogen receptor beta to estrogen response element in situ is independent of estradiol and impaired by its amino terminus | Q46564582 | ||
The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation | Q46779788 | ||
Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action | Q46818342 | ||
Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha | Q46928900 | ||
Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells | Q46944972 | ||
Untangling the human estrogen receptor gene structure | Q48554408 | ||
The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. | Q52514375 | ||
P433 | issue | 1 | |
P304 | page(s) | 4-20 | |
P577 | publication date | 2016-12-05 | |
P1433 | published in | Reproductive Medicine and Biology | Q15762965 |
P1476 | title | Molecular mechanism of estrogen-estrogen receptor signaling | |
P478 | volume | 16 |
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