| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M105711200 |
| P698 | PubMed publication ID | 11694526 |
| P50 | author | Hirohito Sone | Q39956334 |
| Naoya Yahagi | Q42403191 | ||
| Hitoshi Shimano | Q87968959 | ||
| Shun Ishibashi | Q88218386 | ||
| Takashi Matsuzaka | Q90787935 | ||
| Yoshiaki Tamura | Q98200597 | ||
| Akimitsu Takahashi | Q114444335 | ||
| Michiyo Amemiya-Kudo | Q114444338 | ||
| Tomohiro Ide | Q114444339 | ||
| Masanori Nakakuki | Q114444340 | ||
| Tomohiro Yoshikawa | Q114444355 | ||
| Yoko Iizuka | Q114444356 | ||
| Sachiko Tomita | Q114444358 | ||
| Jun-ichi Osuga Ji | Q114444359 | ||
| Takanari Gotoda | Q114444360 | ||
| P2093 | author name string | Hiroaki Okazaki | |
| Ken Ohashi | |||
| Nobuhiro Yamada | |||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | fatty acid | Q61476 |
| P304 | page(s) | 1705-1711 | |
| P577 | publication date | 2001-11-02 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements | |
| P478 | volume | 277 |
| Q30438268 | 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1. |
| Q35890742 | A Phospholipid-Protein Complex from Krill with Antioxidative and Immunomodulating Properties Reduced Plasma Triacylglycerol and Hepatic Lipogenesis in Rats |
| Q37463276 | A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1. |
| Q50931635 | A corn oil-based diet protects against combined ethanol and iron-induced liver injury in a mouse model of hemochromatosis. |
| Q38091672 | A pathway approach to investigate the function and regulation of SREBPs |
| Q37594297 | A plural role for lipids in motor neuron diseases: energy, signaling and structure |
| Q54978460 | Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents. |
| Q37441602 | Activation of testicular orphan receptor 4 by fatty acids |
| Q37157344 | Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm. |
| Q43258438 | Arachidonic acid induces acetyl-CoA carboxylase 1 expression via activation of CREB1. |
| Q39921610 | Atorvastatin decreases stearoyl-CoA desaturase gene expression in THP-1 macrophages incubated with oxidized LDL. |
| Q44366212 | Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP-1 interaction with a specific SCD1 promoter element. |
| Q49365640 | Biomarkers of Amyotrophic Lateral Sclerosis: Current Status and Interest of Oxysterols and Phytosterols |
| Q34545181 | Bone muscle crosstalk targets muscle regeneration pathway regulated by core circadian transcriptional repressors DEC1 and DEC2. |
| Q49379954 | CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. |
| Q42772839 | Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice |
| Q51380703 | Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndrome. |
| Q61862690 | Conjugated linoleic acid and obesity control: efficacy and mechanisms |
| Q46708533 | Consumption of polyunsaturated fat improves the saturated fatty acid-mediated impairment of HDL antioxidant potential |
| Q43273804 | Control of adipogenesis by fatty acids |
| Q41137063 | Coronary heart disease: Significance of liver X receptor α genomics |
| Q84040643 | DHA regulates lipogenesis and lipolysis genes in mice adipose and liver |
| Q50952043 | Dietary Omega-3 Fatty Acids Prevented Adipocyte Hypertrophy by Downregulating DGAT-2 and FABP-4 in a Sex-Dependent Fashion. |
| Q24793805 | Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression |
| Q22251218 | Dietary fats and prevention of type 2 diabetes |
| Q44785856 | Dietary n-3 polyunsaturated fatty acids decrease hepatic triglycerides in Fischer 344 rats |
| Q35812881 | Dietary n-6 polyunsaturated fatty acid deprivation increases docosahexaenoic acid metabolism in rat brain |
| Q35054156 | Dietary omega-3 polyunsaturated fatty acids alter the fatty acid composition of hepatic and plasma bioactive lipids in C57BL/6 mice: a lipidomic approach |
| Q92543202 | Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy |
| Q37145836 | Differential anti-atherosclerotic effects in the innominate artery and aortic sinus by the liver X receptor agonist T0901317 |
| Q53287396 | Diosgenin, the main aglycon of fenugreek, inhibits LXRα activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice. |
| Q48425806 | Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. |
| Q59050854 | Diverse Functions of Secretory Phospholipases A2 |
| Q48622009 | Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat. |
| Q28583521 | Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes |
| Q87305017 | Effect of PUFA-rich plant oil on risk factors of STZ-induced diabetes in Wistar rats |
| Q33321238 | Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics. |
| Q60950066 | Effective Food Ingredients for Fatty Liver: Soy Protein β-Conglycinin and Fish Oil |
| Q36567359 | Effects of Arsenite Exposure during Fetal Development on Energy Metabolism and Susceptibility to Diet-Induced Fatty Liver Disease in Male Mice |
| Q55012697 | Effects of Diets Differing in Composition of 18-C Fatty Acids on Adipose Tissue Thermogenic Gene Expression in Mice Fed High-Fat Diets. |
| Q104461516 | Effects of dietary oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) on cholesterol metabolism in obese type-II diabetic KK-Ay mice |
| Q34855807 | Effects of fatty acids on gene expression: role of peroxisome proliferator-activated receptor alpha, liver X receptor alpha and sterol regulatory element-binding protein-1c |
| Q38705146 | Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes |
| Q42944154 | Eicosapentaenoic acid improves hepatic steatosis independent of PPARα activation through inhibition of SREBP-1 maturation in mice |
| Q35049672 | Essential fatty acid synthesis and its regulation in mammals |
| Q46338428 | Establishment of a hepatocyte line for studying biosynthesis of long-chain polyunsaturated fatty acids from a marine teleost, the white-spotted spinefoot Siganus canaliculatus. |
| Q57373134 | Fatty Acid Regulation of Gene Transcription |
| Q36916109 | Fatty Acid modulation of the endocannabinoid system and the effect on food intake and metabolism. |
| Q43089720 | Fatty acid binding profile of the liver X receptor α. |
| Q40010183 | Fatty acid composition and development of hepatic lipidosis during food deprivation--mustelids as a potential animal model for liver steatosis |
| Q35139141 | Fatty acid signaling: the new function of intracellular lipases |
| Q40674487 | Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells |
| Q45281884 | Fish consumption is inversely associated with the metabolic syndrome |
| Q36584568 | Fish oil -- how does it reduce plasma triglycerides? |
| Q37193003 | Flavonoids as dietary regulators of nuclear receptor activity |
| Q51771664 | FoxO1 represses LXRα-mediated transcriptional activity of SREBP-1c promoter in HepG2 cells. |
| Q24299933 | Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages |
| Q34281664 | Group X secretory phospholipase A2 negatively regulates adipogenesis in murine models |
| Q33924348 | Group X secretory phospholipase A2 regulates the expression of steroidogenic acute regulatory protein (StAR) in mouse adrenal glands |
| Q38293471 | HDLs, diabetes, and metabolic syndrome |
| Q33997122 | Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets |
| Q29620653 | Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids |
| Q36089517 | Hepatocyte Nuclear Factor 4α (HNF4α) Is a Transcription Factor of Vertebrate Fatty Acyl Desaturase Gene as Identified in Marine Teleost Siganus canaliculatus |
| Q24322853 | Human apolipoprotein D overexpression in transgenic mice induces insulin resistance and alters lipid metabolism |
| Q51054009 | Hypolipidemic activity of okra is mediated through inhibition of lipogenesis and upregulation of cholesterol degradation. |
| Q46654257 | Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids |
| Q33432792 | Identification of novel genes and pathways regulating SREBP transcriptional activity |
| Q92052851 | Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease |
| Q82653340 | Influence of a fat overload on lipogenic regulators in metabolic syndrome patients |
| Q46972308 | Influence of an algal triacylglycerol containing docosahexaenoic acid (22 : 6n-3) and docosapentaenoic acid (22 : 5n-6) on cardiovascular risk factors in healthy men and women |
| Q44535882 | Inhibition of cholesterol absorption associated with a PPAR alpha-dependent increase in ABC binding cassette transporter A1 in mice |
| Q42947444 | Intake of n-3 polyunsaturated fatty acids and non-alcoholic fatty liver disease: a cross-sectional study in Japanese men and women |
| Q36244293 | Ligands of Therapeutic Utility for the Liver X Receptors |
| Q33565875 | Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages |
| Q34212899 | Linoleic and α-linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism. |
| Q37339704 | Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR Mutants in Non-Small Cell Lung Cancer |
| Q92551527 | Lipocalin-2 Protects Against Diet-Induced Nonalcoholic Fatty Liver Disease by Targeting Hepatocytes |
| Q39902213 | Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma |
| Q35084303 | Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis |
| Q57117258 | Liver X receptors in lipid signalling and membrane homeostasis |
| Q37727909 | Liver x receptors stimulate lipogenesis in bovine mammary epithelial cell culture but do not appear to be involved in diet-induced milk fat depression in cows |
| Q83972604 | Low docosahexaenoic acid content in plasma phospholipids is associated with increased non-alcoholic fatty liver disease in China |
| Q35203793 | Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment |
| Q26863658 | Mechanisms of gene regulation by fatty acids |
| Q36052468 | Mechanisms of regulation of gene expression by fatty acids |
| Q33993155 | Metabolic switching of human myotubes is improved by n-3 fatty acids |
| Q37439291 | N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha |
| Q38199226 | Natural modulators of liver X receptors |
| Q49334640 | Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease. |
| Q56020294 | Newly Identified Mechanisms of Total Parenteral Nutrition Related Liver Injury |
| Q39771613 | Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose |
| Q43232711 | Nuclear receptors and hepatic lipidogenic enzyme response to a dyslipidemic sucrose-rich diet and its reversal by fish oil n-3 polyunsaturated fatty acids |
| Q38185452 | Nutraceuticals and functional foods in the management of hyperlipidemia. |
| Q43699784 | Oleic acid modulates mRNA expression of liver X receptor (LXR) and its target genes ABCA1 and SREBP1c in human neutrophils. |
| Q24202688 | Omega-3 polyunsaturated fatty acids for non-alcoholic fatty liver disease |
| Q44783820 | Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential |
| Q39151146 | Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact form. |
| Q64994493 | Pathological Implication of Adipocytes in AAA Development and the Rupture. |
| Q46484710 | Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome |
| Q39741460 | Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit. |
| Q36267294 | Polyunsaturated fatty acids: From diet to binding to ppars and other nuclear receptors |
| Q37287426 | Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice. |
| Q92049218 | Poncirin attenuates CCL4-induced liver injury through inhibition of oxidative stress and inflammatory cytokines in mice |
| Q37104877 | Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications |
| Q51478386 | Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver. |
| Q39735993 | Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin. |
| Q35953156 | RGC-32 Deficiency Protects against Hepatic Steatosis by Reducing Lipogenesis. |
| Q37266779 | Regulation of bile acid and cholesterol metabolism by PPARs |
| Q37996638 | Regulation of gene transcription by fatty acids. |
| Q33816670 | Regulation of hepatic gene expression by saturated fatty acids |
| Q40567001 | Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha |
| Q35559701 | Reviews: current topicsrole of nuclear receptors in the regulation of gene expression by dietary fatty acids (review) |
| Q92421871 | Revisiting the Role of LXRs in PUFA Metabolism and Phospholipid Homeostasis |
| Q38303283 | Role of liver X receptor, insulin and peroxisome proliferator activated receptor alpha on in vivo desaturase modulation of unsaturated fatty acid biosynthesis |
| Q34289658 | SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. |
| Q37368394 | SREBPs: physiology and pathophysiology of the SREBP family |
| Q64968997 | Sex-Dependence in the Effect of Pharmaceutical Excipients: Polyoxyethylated Solubilising Excipients Increase Oral Drug Bioavailability in Male but not Female Rats. |
| Q35025259 | Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism |
| Q42856791 | Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c). |
| Q38382991 | Targeting liver X receptors in cancer therapeutics |
| Q37825904 | Targeting liver X receptors in human health: deadlock or promising trail? |
| Q34078921 | The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight |
| Q26766160 | The Deep Correlation between Energy Metabolism and Reproduction: A View on the Effects of Nutrition for Women Fertility |
| Q36398555 | The Niemann-Pick C1 gene is downregulated in livers of C57BL/6J mice by dietary fatty acids, but not dietary cholesterol, through feedback inhibition of the SREBP pathway |
| Q38703765 | The emerging roles of liver X receptors and their ligands in cancer. |
| Q46376652 | The impact of dietary sn-2 palmitic triacylglycerols in combination with docosahexaenoic acid or arachidonic acid on lipid metabolism and host faecal microbiota composition in Sprague Dawley rats |
| Q39029674 | The integration of epigenetics and genetics in nutrition research for CVD risk factors. |
| Q90119144 | The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy |
| Q58801216 | The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain |
| Q27016052 | The role of dietary sugars and de novo lipogenesis in non-alcoholic fatty liver disease |
| Q44548838 | The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression |
| Q33838470 | Therapeutic Applications of Rose Hips from Different Rosa Species. |
| Q38309134 | Trans geometric isomers of EPA decrease LXRalpha-induced cellular triacylglycerol via suppression of SREBP-1c and PGC-1beta. |
| Q45753845 | Up-regulation of stearoyl-CoA desaturase 1 increases liver MUFA content in obese Zucker but not Goto-Kakizaki rats |
| Q50091983 | Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators |
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