scholarly article | Q13442814 |
P2093 | author name string | Grindley ND | |
Joyce CM | |||
Astatke M | |||
P2860 | cites work | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 |
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP | Q27728960 | ||
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP | Q27729369 | ||
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism | Q27729370 | ||
Crystal structure of bacteriophage T7 RNA polymerase at 3.3 Å resolution | Q27729914 | ||
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate | Q27731499 | ||
Structure of DNA polymerase I Klenow fragment bound to duplex DNA | Q27732134 | ||
DNA sequence, structure and gene expression of mycobacteriophage L5: a phage system for mycobacterial genetics | Q28267537 | ||
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor | Q29547710 | ||
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. | Q30400206 | ||
Cocrystal structure of an editing complex of Klenow fragment with DNA | Q33677240 | ||
Thermodynamic parameters for loop formation in RNA and DNA hairpin tetraloops | Q35060336 | ||
Identification, sequencing, and targeted mutagenesis of a DNA polymerase gene required for the extreme radioresistance of Deinococcus radiodurans | Q36101816 | ||
DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity | Q38316828 | ||
Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment) | Q38325804 | ||
Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-). | Q38336666 | ||
Elementary steps in the DNA polymerase I reaction pathway | Q38354582 | ||
Function and structure relationships in DNA polymerases | Q40394926 | ||
Compilation, alignment, and phylogenetic relationships of DNA polymerases | Q40405362 | ||
An attempt to unify the structure of polymerases | Q41204694 | ||
A domain of the Klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity. | Q41432614 | ||
Cloning of the DNA polymerase gene of Bacillus caldotenax and characterization of the gene product | Q43023589 | ||
A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity | Q44945167 | ||
Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant | Q52449519 | ||
Kinetic mechanism of DNA polymerase I (Klenow). | Q52582535 | ||
Photoaffinity labeling of the thymidine triphosphate binding domain in Escherichia coli DNA polymerase I: identification of histidine-881 as the site of cross-linking. | Q54758236 | ||
Identification and amino acid sequence of the deoxynucleoside triphosphate binding site in Escherichia coli DNA polymerase I. | Q54766476 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1945-1954 | |
P577 | publication date | 1995-01-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment). | |
P478 | volume | 270 |
Q57477112 | 2.0 Å resolution crystal structure of human polκ reveals a new catalytic function of N-clasp in DNA replication |
Q73708620 | A carboxylate triad is essential for the polymerase activity of Escherichia coli DNA polymerase I (Klenow fragment). Presence of two functional triads at the catalytic center |
Q40789450 | A mutant T7 RNA polymerase as a DNA polymerase. |
Q70825961 | A novel kinetic analysis to calculate nucleotide affinity of proofreading DNA polymerases. Application to phi 29 DNA polymerase fidelity mutants |
Q34117923 | A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides |
Q36000833 | A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides |
Q43602564 | Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase |
Q38361121 | Binding of the priming nucleotide in the initiation of transcription by T7 RNA polymerase |
Q48059987 | Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization |
Q36148547 | Choosing the right sugar: how polymerases select a nucleotide substrate |
Q43604828 | Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate. |
Q30384959 | Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH. |
Q38312369 | Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli |
Q27748814 | Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution |
Q29616842 | Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. |
Q42846484 | Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates |
Q38295428 | DNA polymerase I of Mycobacterium tuberculosis: functional role of a conserved aspartate in the hinge joining the M and N helices |
Q33851808 | DNA polymerase of the T4-related bacteriophages |
Q39718429 | Deoxy- and dideoxynucleotide discrimination and identification of critical 5' nuclease domain residues of the DNA polymerase I from Mycobacterium tuberculosis |
Q39743644 | Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases |
Q35272411 | Directed evolution of polymerase function by compartmentalized self-replication |
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Q30897941 | Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha |
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Q38300589 | Incoming nucleotide binds to Klenow ternary complex leading to stable physical sequestration of preceding dNTP on DNA. |
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Q38329025 | Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site |
Q38354518 | Local conformations and competitive binding affinities of single- and double-stranded primer-template DNA at the polymerization and editing active sites of DNA polymerases |
Q54567474 | Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I. |
Q36281363 | Mapping of ATP binding regions in poly(A) polymerases by photoaffinity labeling and by mutational analysis identifies a domain conserved in many nucleotidyltransferases |
Q46840914 | Measurement of incorporation kinetics of non-fluorescent native nucleotides by DNA polymerases using fluorescence microscopy |
Q36563030 | Molecular cloning of Drosophila mus308, a gene involved in DNA cross-link repair with homology to prokaryotic DNA polymerase I genes |
Q38343144 | Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DN |
Q34460889 | Mutant Thermotoga neapolitana DNA polymerase I: altered catalytic properties for non-templated nucleotide addition and incorporation of correct nucleotides |
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Q41065136 | Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases |
Q42065679 | Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphate |
Q43207183 | Mutations in the middle domain of yeast poly(A) polymerase affect interactions with RNA but not ATP. |
Q28145203 | Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B |
Q24685513 | Polymerase structures and function: variations on a theme? |
Q46751740 | Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus |
Q37162953 | Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766. |
Q38358840 | Presence of 18-A long hydrogen bond track in the active site of Escherichia coli DNA polymerase I (Klenow fragment). Its requirement in the stabilization of enzyme-template-primer complex |
Q39492281 | Protein-DNA interactions in the ori region of the Mycobacterium fortuitum plasmid pAL5000. |
Q33598642 | RB69 DNA polymerase structure, kinetics, and fidelity |
Q36817752 | Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure |
Q77896965 | Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment) |
Q37482169 | Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. |
Q36228571 | Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. |
Q71706996 | Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity |
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Q38354757 | Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs. |
Q36288580 | Structure and mechanism of DNA polymerases |
Q28272479 | Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia |
Q38356754 | The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect ones |
Q77892158 | The mechanism of action of T7 DNA polymerase |
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