Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells

scientific article published on 07 September 2006

Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPGI.00200.2006
P698PubMed publication ID16959952

P2093author name stringAnping Chen
Shizhong Zheng
P2860cites workTransforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementQ24629916
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Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organizationQ28567374
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 geneQ29616540
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Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methodsQ33920115
TGFbeta1 in liver fibrosis: time to change paradigms?Q34322705
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Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: a reviewQ34568687
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinasesQ35201617
UV irradiation activates JNK and increases alphaI(I) collagen gene expression in rat hepatic stellate cellsQ38330108
TGF-beta 1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequenceQ38341183
Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gammaQ40907616
1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiationQ40914117
Expression of connective tissue growth factor in experimental rat and human liver fibrosisQ40926848
From receptor to nucleus: the Smad pathwayQ41600955
Peroxisome proliferator-activated receptors and hepatic stellate cell activationQ41758990
Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitroQ42808663
The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expressionQ43002494
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.Q44021747
Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growthQ44378715
Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cellsQ44710999
Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cellsQ44939104
Hepatic fibrosis as wound repair: a progress reportQ45111395
Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factorQ46818402
TGF-beta isoforms in alcoholic liver diseaseQ47866440
Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in ratsQ58215294
P433issue1
P921main subjectcurcuminQ312266
P304page(s)G113-23
P577publication date2006-09-07
P1433published inAmerican Journal of Physiology - Gastrointestinal and Liver PhysiologyQ15765756
P1476titleDisruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells
P478volume292

Reverse relations

cites work (P2860)
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