| P50 | author | Carol Feghali-Bostwick | Q59590181 |
| | Kazuhiro Komura | Q59695182 |
| P2093 | author name string | John Varga | |
| | Minghua Wu | |
| | Jun Wei | |
| | Michael L Whitfield | |
| | Manu Jain | |
| | Asish K Ghosh | |
| | Qi-Quan Huang | |
| | Jennifer L Sargent | |
| P2860 | cites work | Inhibition of adipogenesis by Wnt signaling | Q22254771 |
| | Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells | Q24656526 |
| | Mechanisms of TGF-beta signaling from cell membrane to the nucleus | Q27860785 |
| | PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro | Q28146187 |
| | The mechanisms of action of PPARs | Q28216953 |
| | Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway | Q28239297 |
| | The organization, promoter analysis, and expression of the human PPARgamma gene | Q28244071 |
| | Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways | Q28574712 |
| | Fat and beyond: the diverse biology of PPARgamma | Q29615416 |
| | Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene | Q29616540 |
| | Molecular subsets in the gene expression signatures of scleroderma skin | Q33354088 |
| | Effects of PPAR gamma ligands on TGF-beta1-induced epithelial-mesenchymal transition in alveolar epithelial cells. | Q33748854 |
| | Deficient Smad7 expression: a putative molecular defect in scleroderma | Q34021184 |
| | Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist | Q34466845 |
| | C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway | Q35004645 |
| | Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis | Q35087744 |
| | Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia | Q35089001 |
| | Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma | Q35102837 |
| | Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma | Q35170133 |
| | Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality | Q35629015 |
| | Systemic sclerosis: a prototypic multisystem fibrotic disorder | Q35649427 |
| | Sequential induction of pro- and anti-inflammatory prostaglandins and peroxisome proliferators-activated receptor-gamma during normal wound healing: a time course study | Q35740906 |
| | A mouse model of conditional lipodystrophy | Q36082198 |
| | The many faces of PPARgamma | Q36344625 |
| | Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators. | Q36743124 |
| | Molecular pathways as novel therapeutic targets in systemic sclerosis | Q36961452 |
| | Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma | Q37071874 |
| | Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice | Q37201578 |
| | Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator | Q37326935 |
| | A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity | Q37402787 |
| | The role of plasminogen activator inhibitor 1 in renal and cardiovascular diseases. | Q37423754 |
| | Transforming growth factor beta as a therapeutic target in systemic sclerosis | Q37428739 |
| | Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis | Q37497600 |
| | Selective peroxisome proliferator-activated receptor gamma (PPARgamma) modulation as a strategy for safer therapeutic PPARgamma activation | Q37631296 |
| | Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells | Q38309898 |
| | Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2. | Q38330620 |
| | A dominant negative PPARgamma mutant shows altered cofactor recruitment and inhibits adipogenesis in 3T3-L1 cells. | Q40657052 |
| | Peroxisome proliferator-activated receptors and hepatic stellate cell activation | Q41758990 |
| | Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma | Q42459998 |
| | Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators | Q42491309 |
| | Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma | Q42506187 |
| | Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-gamma in human proximal renal tubular cells. | Q42507436 |
| | Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma activation | Q42518271 |
| | Connective tissue growth factor inhibits adipocyte differentiation | Q42811047 |
| | Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia | Q42817965 |
| | Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts | Q43223419 |
| | Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. | Q44021747 |
| | Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction | Q44243308 |
| | Peroxisome Proliferator–Activated Receptor γ Activity Is Deficient in Alveolar Macrophages in Pulmonary Sarcoidosis | Q44598265 |
| | Characterization of human fibrocytes as circulating adipocyte progenitors and the formation of human adipose tissue in SCID mice | Q44978937 |
| | Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts | Q45184192 |
| | PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis | Q45285303 |
| | PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta | Q46252518 |
| | PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis | Q46830543 |
| | Wnt10b inhibits development of white and brown adipose tissues | Q47364038 |
| | Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. | Q52543659 |
| | Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis. | Q54595302 |
| | Skin involvement in scleroderma--where histological and clinical scores meet | Q58814291 |
| | Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3 | Q60537832 |
| | Alteration of Subcutaneous Tissue in Systemic Scleroderma | Q67279266 |
| | Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts | Q73628355 |
| | Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts | Q79795007 |
| | Rosiglitazone and cardiovascular risk | Q80367645 |
| | IL-13 downregulates PPAR-gamma/heme oxygenase-1 via ER stress-stimulated calpain activation: aggravation of activated microglia death | Q83176765 |
| | Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis | Q84483475 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e13778 | |
| P577 | publication date | 2010-11-02 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis | |
| P478 | volume | 5 | |