Identification and expression analysis of leptin-regulated immediate early response and late target genes

scientific article published on May 2000

Identification and expression analysis of leptin-regulated immediate early response and late target genes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/0264-6021:3480055
P932PMC publication ID1221035
P698PubMed publication ID10794713
P5875ResearchGate publication ID12522104

P2093author name stringA Verhee
J Tavernier
J Vandekerckhove
S Eyckerman
D Broekaert
J H Beattie
W Waelput
P2860cites workStrategies and potential molecular targets for obesity treatmentQ48035230
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesityQ22241899
Positional cloning of the mouse obese gene and its human homologueQ22251285
The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticityQ24529853
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptorsQ24629394
Transcriptional regulation of squalene epoxidase by sterols and inhibitors in HeLa cellsQ28278204
Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer culturesQ28334611
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppressionQ28594263
Leptin and the regulation of body weight in mammalsQ29615976
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjectsQ29617231
Weight-reducing effects of the plasma protein encoded by the obese geneQ29617934
Effects of the obese gene product on body weight regulation in ob/ob miceQ29617935
Role of leptin in the neuroendocrine response to fastingQ29618866
Identification and expression cloning of a leptin receptor, OB-RQ29620255
Rodent mutant models of obesity and their correlations to human obesityQ33631946
Overexpression of the obese (ob) gene in adipose tissue of human obese subjectsQ34297440
Increased obese mRNA expression in omental fat cells from massively obese humansQ34297446
Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networksQ34301257
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db miceQ34376178
Abnormal splicing of the leptin receptor in diabetic miceQ34379335
Leptin and the regulation of body weightQ34454916
Identifying differences in mRNA expression by representational difference analysis of cDNAQ35004368
Obesity and hyperleptinemia in metallothionein (-I and -II) null miceQ35679481
Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factorQ35834619
Leptin expression and action: new experimental paradigmsQ36004692
Recent excitement regarding metallothioneinQ36062051
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.Q36246132
13C NMR study of the effects of leptin treatment on kinetics of hepatic intermediary metabolismQ36488153
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.Q36837473
Regulation, Linkage, and Sequence of Mouse Metallothionein I and II GenesQ36945463
Regulation of fatty acid homeostasis in cells: novel role of leptinQ37182555
Defective STAT signaling by the leptin receptor in diabetic miceQ37509613
The role of neuropeptide Y in the antiobesity action of the obese gene productQ38290434
Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissuesQ38322266
Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expressionQ38330432
Leptin action in intestinal cellsQ38333089
Biological action of leptin as an angiogenic factorQ38333557
Identification of SOCS-3 as a potential mediator of central leptin resistanceQ38335615
Activation of nuclear factor kappaB: potential role in metallothionein-mediated mitogenic response.Q38336770
Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistanceQ38347472
Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridizationQ38347704
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db miceQ38353583
Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridizationQ38356905
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysisQ40016977
Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.Q40913923
Development of a radioimmunoassay for rat liver metallothionein-I and its application to the analysis of rat plasma and kidneysQ42144561
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signalingQ42449457
Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genesQ42490264
Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol esterQ42501657
A human leptin mutant induces weight gain in normal miceQ47311993
P407language of work or nameEnglishQ1860
P304page(s)55-61
P577publication date2000-05-01
P1433published inBiochemical JournalQ864221
P1476titleIdentification and expression analysis of leptin-regulated immediate early response and late target genes
P478volume348 Pt 1

Reverse relations

cites work (P2860)
Q36369639A mediator role for metallothionein in tumor necrosis factor-induced lethal shock.
Q36220879Cell signals influencing hepatic fibrosis
Q42857638Different physiology of interferon-α/-γ in models of liver regeneration in the rat.
Q51540819Enhancement of MT synthesis by leptin in fasted mice.
Q38298178Gene expression of adrenomedullin, leptin, their receptors and neuropeptide Y in hormone-secreting and non-functioning pituitary adenomas, meningiomas and malignant intracranial tumours in humans
Q37207519Genes regulated by caloric restriction have unique roles within transcriptional networks
Q36296837IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer
Q34325863Immunoreactivities of PPARγ2, leptin and leptin receptor in oviduct of Chinese brown frog during breeding period and pre-hibernation
Q36725696Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice
Q34548469Leptin and reproduction: a review
Q38288972Leptin deficiency reduces but does not eliminate the development of hepatic fibrosis in mice infected with Schistosoma mansoni
Q28575890Leptin induces inflammation-related genes in RINm5F insulinoma cells
Q40035458Leptin regulates chondrogenic differentiation in ATDC5 cell-line through JAK/STAT and MAPK pathways
Q26859118Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals
Q38357572Leptin-induced transactivation of NPY gene promoter mediated by JAK1, JAK2 and STAT3 in the neural cell lines
Q30860835MAPPIT: a cytokine receptor-based two-hybrid method in mammalian cells.
Q36068166Metallothionein and the biology of aging
Q37770461Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases
Q42816086PAP/HIP protein is an obesogenic factor
Q35747457STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers
Q42503676Specific expression of annexin A8 in adult murine stratified epithelia
Q39892992The Cdk5/p35 kinases modulate leptin-induced STAT3 signaling
Q37655073The Leptin Receptor Complex: Heavier Than Expected?
Q36692504Transcriptional profiling of murine organ genes in response to infection with Bacillus anthracis Ames spores
Q28511147p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I

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