Identification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis

scientific article published on 05 May 2006

Identification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M601785200
P698PubMed publication ID16679316

P50authorDavid R GoodlettQ87441186
P2093author name stringScott A Shaffer
Catalin E Doneanu
Sidney D Nelson
Elinor T Adman
Qiuxia Gao
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Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.Q43563729
Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactionsQ43577472
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Measurement of cytochrome P450 2E1 activity in rat tracheobronchial airways using high-performance liquid chromatography with electrochemical detection.Q45932526
Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.Q45996870
Refinement and structural analysis of bovine cytochrome b5 at 1.5 A resolutionQ47983394
A new and sensitive on-line liquid chromatography/mass spectrometric approach for top-down protein analysis: the comprehensive analysis of human growth hormone in an E. coli lysate using a hybrid linear ion trap/Fourier transform ion cyclotron resonQ51611712
Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.Q52595110
Interaction between cytochrome P450 2B1 and cytochrome bs: inhibition by synthetic peptides indicates a role for P450 residues Lys-122 and Arg-125.Q53471557
Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.Q54578311
Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.Q54630718
Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass SpectrometryQ58039486
P4510describes a project that usesmass spectrometryQ180809
P433issue29
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)20404-20417
P577publication date2006-05-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis
P478volume281

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