| scholarly article | Q13442814 |
| P2093 | author name string | Chang YT | |
| Loew G | |||
| Gruenke L | |||
| Waskell L | |||
| Bridges A | |||
| Vakser IA | |||
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| Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S | Q43998364 | ||
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| Refinement and structural analysis of bovine cytochrome b5 at 1.5 A resolution | Q47983394 | ||
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| Interaction between cytochrome P450 2B1 and cytochrome bs: inhibition by synthetic peptides indicates a role for P450 residues Lys-122 and Arg-125. | Q53471557 | ||
| Specificity of the cytochrome P-450 interaction with cytochrome b5. | Q53471625 | ||
| A new spectral intermediate associated with cytochrome P-450 function in liver microsomes. | Q53876638 | ||
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| Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme. | Q54652897 | ||
| Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities | Q59153257 | ||
| P433 | issue | 27 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 17036-17049 | |
| P577 | publication date | 1998-07-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase. | |
| P478 | volume | 273 |
| Q37409857 | 13C-Methyl isocyanide as an NMR probe for cytochrome P450 active sites |
| Q44604937 | 5α-reduced C21 steroids are substrates for human cytochrome P450c17 |
| Q57975741 | A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs |
| Q30633058 | A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. |
| Q35551589 | A systematic study of low-resolution recognition in protein--protein complexes |
| Q42034704 | Allelic variation in the Depressaria pastinacella CYP6AB3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential interactions with cytochrome P450 reductase |
| Q34370833 | Allosteric phenomena in cytochrome P450-catalyzed monooxygenations |
| Q27642370 | An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution |
| Q37866680 | Another look at the interaction between mitochondrial cytochrome c and flavocytochrome b (2). |
| Q46703807 | Association of cytochrome P450 enzymes is a determining factor in their catalytic activity |
| Q33891038 | CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus |
| Q33220807 | Characterization and calculation of a cytochrome c-cytochrome b5 complex using NMR data |
| Q36928692 | Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation |
| Q41807142 | Comparison of the complexes formed by cytochrome P450cam with cytochrome b5 and putidaredoxin, two effectors of camphor hydroxylase activity |
| Q27667024 | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding |
| Q46913522 | Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modeling |
| Q37711781 | Congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency: functional consequences of four CYP11B1 mutations |
| Q37422674 | Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges. |
| Q37179263 | Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver |
| Q36598930 | Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5). |
| Q33663887 | Cross-linking of human cytochrome P450 2B6 to NADPH-cytochrome P450 reductase: Identification of a potential site of interaction |
| Q27655307 | Crystal Structures of Cytochrome P450 2B4 in Complex with the Inhibitor 1-Biphenyl-4-methyl-1 H -imidazole: Ligand-Induced Structural Response through α-Helical Repositioning , |
| Q22008812 | Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution |
| Q28271636 | Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR |
| Q42324882 | Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production |
| Q35015953 | Cytochrome-P450 phosphorylation as a functional switch |
| Q36473495 | Cytochromes P450--a family of proteins and scientists-understanding their relationships |
| Q44608181 | Determination of the Rate of Reduction of Oxyferrous Cytochrome P450 2B4 by 5-Deazariboflavin Adenine Dinucleotide T491V Cytochrome P450 Reductase |
| Q50016590 | Direct Molecular Fishing of New Protein Partners for Human Thromboxane Synthase. |
| Q38270218 | Docking of protein models |
| Q35175018 | Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. |
| Q36012132 | Effects of ionic strength on the functional interactions between CYP2B4 and CYP1A2. |
| Q35608108 | Effects of membrane mimetics on cytochrome P450-cytochrome b5 interactions characterized by NMR spectroscopy. |
| Q58796074 | Effects of polymorphic variation on the thermostability of heterogenous populations of CYP3A4 and CYP2C9 enzymes in solution |
| Q79085995 | Examining the mechanism of stimulation of cytochrome P450 by cytochrome b5: the effect of cytochrome b5 on the interaction between cytochrome P450 2B4 and P450 reductase |
| Q36453123 | Experimental documentation of the structural consequences of hydrogen-bonding interactions to the proximal cysteine of a cytochrome P450. |
| Q29870592 | Expression, purification and characterisation of a Bacillus subtilis ferredoxin: a potential electron transfer donor to cytochrome P450 BioI. |
| Q35009300 | Fast regulation of cytochrome P450 activities by phosphorylation and consequences for drug metabolism and toxicity |
| Q73435884 | Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells |
| Q46800583 | Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego. |
| Q87362310 | Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation |
| Q35187813 | Functional interaction of cytochrome P450 with its redox partners: a critical assessment and update of the topology of predicted contact regions |
| Q37034584 | Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers |
| Q58581001 | Genetic Polymorphisms and In Silico Mutagenesis Analyses of CYP2C9, CYP2D6, and CYPOR Genes in the Pakistani Population |
| Q36992700 | Global analysis of protein-protein interactions reveals multiple CYP2E1-reductase complexes. |
| Q37648157 | Hepatic cytochrome P450 ubiquitination: conformational phosphodegrons for E2/E3 recognition? |
| Q41666716 | Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame |
| Q36013302 | Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions |
| Q48336005 | High warfarin sensitivity in carriers of CYP2C9*35 is determined by the impaired interaction with P450 oxidoreductase. |
| Q38272420 | How common is the funnel-like energy landscape in protein-protein interactions? |
| Q33817658 | How does the reductase help to regulate the catalytic cycle of cytochrome P450 3A4 using the conserved water channel? |
| Q33772407 | Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a. |
| Q35055500 | Human liver cytochrome P450 3A4 ubiquitination: molecular recognition by UBC7-gp78 autocrine motility factor receptor and UbcH5a-CHIP-Hsc70-Hsp40 E2-E3 ubiquitin ligase complexes |
| Q41176588 | Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes. |
| Q34166436 | Identification of a novel domain of fibroblast growth factor 2 controlling its angiogenic properties |
| Q35032512 | Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol. |
| Q38313562 | Identification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis |
| Q40880012 | Identification of universal selectivity-determining positions in cytochrome P450 monooxygenases by systematic sequence-based literature mining |
| Q42041436 | Ile115Leu mutation in the SRS1 region of an insect cytochrome P450 (CYP6B1) compromises substrate turnover via changes in a predicted product release channel |
| Q37076326 | Influence of protein-protein interactions on the cellular localization of cytochrome P450. |
| Q43149378 | Insights into the role of substrates on the interaction between cytochrome b5 and cytochrome P450 2B4 by NMR. |
| Q36497669 | Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism |
| Q34098945 | Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects |
| Q24310223 | Involvement of NADPH in the interaction between heme oxygenase-1 and cytochrome P450 reductase |
| Q41353184 | Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c. |
| Q30369811 | Kinetic and structural characterization of the interaction between the FMN binding domain of cytochrome P450 reductase and cytochrome c. |
| Q38282896 | Leu432Val polymorphism in CYP1B1 as a susceptible factor towards predisposition to primary open-angle glaucoma |
| Q27621446 | Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity |
| Q28569380 | Mass spectrometric identification of lysine residues of heme oxygenase-1 that are involved in its interaction with NADPH-cytochrome P450 reductase |
| Q38499341 | Mechanistic basis of electron transfer to cytochromes p450 by natural redox partners and artificial donor constructs |
| Q24609983 | Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site |
| Q48258823 | Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1. |
| Q73123239 | Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features |
| Q41865082 | Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant |
| Q36812605 | Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification |
| Q33834097 | Molecular modeling of mammalian cytochromes P450: application to study enzyme function |
| Q37078680 | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone |
| Q30537968 | NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family |
| Q35184715 | NMR-derived models of amidopyrine and its metabolites in complexes with rabbit cytochrome P450 2B4 reveal a structural mechanism of sequential N-dealkylation |
| Q37701054 | New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners |
| Q52993060 | Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b₅. |
| Q37611698 | Physical Studies of P450-P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures |
| Q57975737 | Picturing the Membrane-assisted Choreography of Cytochrome P450 with Lipid Nanodiscs |
| Q37429225 | Plasticity of CYP2B enzymes: structural and solution biophysical methods |
| Q35188159 | Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase c |
| Q30357090 | Polymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure. |
| Q27675674 | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis |
| Q33736588 | Probing the transmembrane structure and dynamics of microsomal NADPH-cytochrome P450 oxidoreductase by solid-state NMR. |
| Q41917512 | Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles |
| Q24307533 | Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase |
| Q34126229 | Protein engineering of cytochromes P-450. |
| Q36472763 | Reaction of human cytochrome P450 3A4 with peroxynitrite: nitrotyrosine formation on the proximal side impairs its interaction with NADPH-cytochrome P450 reductase |
| Q41808959 | Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase |
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| Q40124142 | Role of the Proximal Cysteine Hydrogen Bonding Interaction in Cytochrome P450 2B4 Studied by Cryoreduction, Electron Paramagnetic Resonance, and Electron-Nuclear Double Resonance Spectroscopy |
| Q43645369 | Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase |
| Q27684706 | Structural and Functional Characterization of a Cytochrome P450 2B4 F429H Mutant with an Axial Thiolate–Histidine Hydrogen Bond |
| Q50140978 | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. |
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| Q42625456 | Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding |
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| Q36910210 | Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR. |
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| Q36680194 | The action of cytochrome b(5) on CYP2E1 and CYP2C19 activities requires anionic residues D58 and D65. |
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