Leptin and leucine synergistically regulate protein metabolism in C2C12 myotubes and mouse skeletal muscles

scientific article

Leptin and leucine synergistically regulate protein metabolism in C2C12 myotubes and mouse skeletal muscles is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1017/S0007114512004849
P698PubMed publication ID23211060

P2093author name stringZhimin Huang
Junjun Wang
Shiyan Qiao
Xiangfang Zeng
Xiangbing Mao
P2860cites workEffects of leptin adipose tissue lipoprotein lipase in the obese ob/ob mouseQ77581839
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanismsQ79953652
A deficiency or excess of dietary threonine reduces protein synthesis in jejunum and skeletal muscle of young pigsQ80357840
Fractional protein synthesis rates measured by an intraperitoneal injection of a flooding dose of L-[ring-2H5]phenylalanine in pigsQ80822988
Dietary arginine supplementation during early pregnancy enhances embryonic survival in ratsQ81670543
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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistanceQ28240815
The leptin receptorQ28509967
Fat diet affects leptin receptor levels in the rat cerebellumQ28567402
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjectsQ29617231
Effects of the obese gene product on body weight regulation in ob/ob miceQ29617935
Identification and expression cloning of a leptin receptor, OB-RQ29620255
Model for the regulation of energy balance and adiposity by the central nervous systemQ33590911
Human IL6 enhances leptin action in miceQ33628094
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptorQ34373507
Leucine nutrition in animals and humans: mTOR signaling and beyondQ37902970
Amino acid flooding doses for measuring rates of protein synthesisQ38159964
Regulation of dietary energy level and oil source on leptin and its long form receptor mRNA expression of the adipose tissues in growing pigsQ38316918
Molecular cloning, tissue distribution and ontogenetic expression of Xiang pig chemerin and its involvement in regulating energy metabolism through Akt and ERK1/2 signaling pathwaysQ39530094
Leucine promotes leptin receptor expression in mouse C2C12 myotubes through the mTOR pathwayQ39740399
Leptin prevents the metabolic effects of adiponectin in L6 myotubesQ39820031
Leucine stimulates HGF production by hepatic stellate cells through mTOR pathwayQ40139656
Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinaseQ40193113
Porcine leptin inhibits protein breakdown and stimulates fatty acid oxidation in C2C12 myotubesQ40607035
Leptin stimulates glucose uptake in C2C12 muscle cells by activation of ERK2.Q40908774
Myostatin regulates preadipocyte differentiation and lipid metabolism of adipocyte via ERK1/2.Q42811575
Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigsQ43062070
Insulin modulates leptin-induced STAT3 activation in rat hypothalamus.Q43668023
Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylationQ43935389
Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction systemQ44368203
Leptin as an adjunct of insulin therapy in insulin-deficient diabetesQ44556262
Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat HepatocytesQ44650510
Regulation of muscle protein degradation, not synthesis, by dietary leucine in rats fed a protein-deficient dietQ46372074
Leucine suppresses myofibrillar proteolysis by down-regulating ubiquitin-proteasome pathway in chick skeletal musclesQ46695281
A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscleQ46728790
Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathwayQ46886038
The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in ratsQ47915397
Short-term effects of leptin on skeletal muscle protein metabolism in the ratQ60403880
Amino acid excesses for young pigs: effects of excess methionine, tryptophan, threonine or leucineQ70345054
Use of plasma urea nitrogen as a rapid response criterion to determine the lysine requirement of pigs2Q71847352
Leucine-supplemented meal feeding for ten days beneficially affects postprandial muscle protein synthesis in old ratsQ73209134
P433issue2
P304page(s)256-264
P577publication date2012-12-05
P1433published inBritish Journal of NutritionQ4970206
P1476titleLeptin and leucine synergistically regulate protein metabolism in C2C12 myotubes and mouse skeletal muscles
P478volume110

Reverse relations

cites work (P2860)
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Q35763718Dietary Leucine Supplementation Improves the Mucin Production in the Jejunal Mucosa of the Weaned Pigs Challenged by Porcine Rotavirus
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