| human | Q5 |
| P6178 | Dimensions author ID | 016564250462.13 |
| P496 | ORCID iD | 0000-0003-0033-9138 |
| P2038 | ResearchGate profile ID | John-Cooke-3 |
| P1153 | Scopus author ID | 7202378672 |
| P69 | educated at | Cornell University | Q49115 |
| Wayne State University School of Medicine | Q267322 | ||
| Mayo Clinic Graduate School of Biomedical Sciences | Q25108546 | ||
| P108 | employer | Harvard Medical School | Q49121 |
| University of Chicago | Q131252 | ||
| Houston Methodist Research Institute | Q104628981 | ||
| Stanford University School of Medicine | Q4115969 | ||
| P734 | family name | Cooke | Q658676 |
| Cooke | Q658676 | ||
| Cooke | Q658676 | ||
| P735 | given name | John | Q4925477 |
| John | Q4925477 | ||
| P106 | occupation | researcher | Q1650915 |
| P21 | sex or gender | male | Q6581097 |
| Q35540855 | A Novel Mechanism for Pulmonary Arterial Hypertension? |
| Q53590120 | A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration. |
| Q36283545 | A comparison of the pro-angiogenic potential of human induced pluripotent stem cell derived endothelial cells and induced endothelial cells in a murine model of peripheral arterial disease. |
| Q39968344 | A compendium on peripheral arterial disease |
| Q37510205 | A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis |
| Q30497058 | A matrix micropatterning platform for cell localization and stem cell fate determination. |
| Q35019853 | A novel and potent inhibitor of dimethylarginine dimethylaminohydrolase: a modulator of cardiovascular nitric oxide |
| Q40131722 | A novel bioluminescent tumor model of human renal cancer cell lines: an in vitro and in vivo characterization |
| Q44478662 | A peculiar result and a fanciful hypothesis regarding L-arginine |
| Q44907812 | A pilot study of L-arginine supplementation on functional capacity in peripheral arterial disease. |
| Q51350033 | A validated biomarker panel to identify peripheral artery disease. |
| Q48482923 | ADMA increases arterial stiffness and decreases cerebral blood flow in humans |
| Q46127047 | ADMA regulates angiogenesis: genetic and metabolic evidence |
| Q46917791 | ADMA: an emerging cardiovascular risk factor |
| Q38888721 | AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling. |
| Q81570996 | Abnormal cardiovascular response to exercise in patients with peripheral arterial disease: Implications for management |
| Q34034126 | Activation of innate immunity is required for efficient nuclear reprogramming |
| Q54587707 | Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. |
| Q36661613 | Aligned nanofibrillar collagen regulates endothelial organization and migration. |
| Q37505831 | Aligned nanofibrillar collagen scaffolds - Guiding lymphangiogenesis for treatment of acquired lymphedema. |
| Q35660118 | Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis |
| Q44677251 | An endogenous inhibitor of nitric oxide synthase regulates endothelial adhesiveness for monocytes |
| Q40568972 | Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial |
| Q46037040 | Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits. |
| Q35126339 | Assessing endothelial vasodilator function with the Endo-PAT 2000. |
| Q35828701 | Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies |
| Q80457511 | Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury |
| Q51756269 | Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study. |
| Q44686239 | Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase |
| Q46687461 | Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus |
| Q35090446 | Asymmetric dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause mortality in patients with peripheral arterial disease. |
| Q33295304 | Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies |
| Q35890008 | Bioluminescence imaging of stem cell-based therapeutics for vascular regeneration |
| Q35170187 | Biomarkers of peripheral arterial disease. |
| Q36123176 | Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial |
| Q34807168 | Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial. |
| Q30485381 | Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. |
| Q40941602 | Building a partnership between vascular medicine and vascular surgery: a coalition for the future of vascular care |
| Q31139539 | Capillary electrophoretic and micellar electrokinetic separations of asymmetric dimethyl-L-arginine and structurally related amino acids: quantitation in human plasma. |
| Q52718032 | Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. |
| Q41688969 | Cardiovascular effects of L-arginine |
| Q41266826 | Cardiovascular effects of exercise: role of endothelial shear stress |
| Q35123792 | Cell-free production of transducible transcription factors for nuclear reprogramming. |
| Q80112074 | Changes in coronary arterial dimensions early after cardiac transplantation |
| Q37591188 | Characterization of a fluorescent probe for imaging nitric oxide. |
| Q35033211 | Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? |
| Q35117369 | Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor. |
| Q42113835 | Chronic exposure to nicotine impairs cholinergic angiogenesis |
| Q48285536 | Clinical and socioeconomic factors associated with unrecognized peripheral artery disease |
| Q30568774 | Concurrent generation of functional smooth muscle and endothelial cells via a vascular progenitor |
| Q42794801 | Critical determinants of limb ischemia |
| Q42791219 | DDAH says NO to ADMA |
| Q42716627 | DDAH: a target for vascular therapy? |
| Q46305005 | Decongestive lymphatic therapy for patients with cancer-related or primary lymphedema |
| Q35174462 | Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. |
| Q45171320 | Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay |
| Q37990325 | Development of pluripotent stem cells for vascular therapy |
| Q44774814 | Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia |
| Q46024028 | Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. |
| Q46086523 | Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit |
| Q41836018 | Dietary nitrate, nitric oxide, and restenosis |
| Q36853950 | Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. |
| Q35190437 | Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity |
| Q46170586 | Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury |
| Q33935685 | Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators. |
| Q45871894 | Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis |
| Q33563457 | Discovery of novel determinants of endothelial lineage using chimeric heterokaryons |
| Q37440685 | Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk? |
| Q78346338 | Does leptin cause vascular disease? |
| Q92613681 | Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome |
| Q74685352 | Effect of cyclosporine on chronic graft vascular disease in a rat cardiac isograft model |
| Q42164909 | Effect of local delivery of L-arginine on in-stent restenosis in humans |
| Q41482128 | Effect of physical activity assessment on prognostication for peripheral artery disease and mortality |
| Q37297962 | Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia. |
| Q46051477 | Effects of fluid-induced shear on articular chondrocyte morphology and metabolism in vitro |
| Q46733983 | Effects of growth factors and L-arginine on ischemic skin flaps in rats |
| Q33532341 | Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion |
| Q33991356 | Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease |
| Q44212415 | Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases |
| Q41753866 | Endothelial dysfunction in hypercholesterolemia is reversed by a nutritional product designed to enhance nitric oxide activity |
| Q44545493 | Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. |
| Q37397988 | Endothelial nicotinic acetylcholine receptors and angiogenesis. |
| Q46471410 | Endothelial progenitor cells participate in nicotine-mediated angiogenesis |
| Q36527462 | Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease |
| Q46089799 | Exercise patterns and cardiovascular fitness of patients with peripheral arterial disease |
| Q43295551 | Extensive characterization of the human DDAH1 transgenic mice |
| Q27329677 | FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats |
| Q112752533 | Fli1+ cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis |
| Q34327487 | Flow, NO, and atherogenesis |
| Q44474843 | Flow-responsive remodeling after angioplasty is enhanced by high cholesterol diet. Prevention with pyrrolidine dithiocarbamate |
| Q46456129 | Gender differences in perception of PAD: a pilot study. |
| Q40923166 | Gene transfer of nitric oxide synthase: effects on endothelial biology |
| Q43724491 | Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. |
| Q36680405 | Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium |
| Q37127078 | Genetics of peripheral artery disease |
| Q70504116 | High-dose vitamin A therapy for Darier's disease |
| Q44158689 | Homocysteine impairs coronary microvascular dilator function in humans |
| Q46762585 | Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor |
| Q36892867 | How May Proton Pump Inhibitors Impair Cardiovascular Health? |
| Q35117350 | Hypercholesterolemia impairs exercise capacity in mice |
| Q71073059 | Hypertension-enhanced monocyte adhesion in experimental atherosclerosis |
| Q49171170 | Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials |
| Q49191813 | Imaging vascular nicotine receptors: a new window onto vascular disease |
| Q48425263 | In Memoriam of John T. Shepherd, MD, DSc. |
| Q35540671 | Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance |
| Q38280717 | Innate immunity and epigenetic plasticity in cellular reprogramming. |
| Q44961037 | Isoflavones improve vascular reactivity in post-menopausal women with hypercholesterolemia |
| Q44701501 | L-arginine supplementation in peripheral arterial disease: no benefit and possible harm |
| Q37434748 | LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration |
| Q58949693 | Letter by Kielstein et al Regarding Article, “Renal Function as a Predictor of Outcome in a Broad Spectrum of Patients With Heart Failure” |
| Q44070123 | Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction". |
| Q79746097 | Limb hemodynamics are not predictive of functional capacity in patients with PAD |
| Q35154228 | Low lifetime recreational activity is a risk factor for peripheral arterial disease |
| Q43180251 | Lymphangiogenesis: a potential new therapy for lymphedema? |
| Q35228483 | Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes. |
| Q37085686 | Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. |
| Q44037432 | Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes |
| Q42922925 | MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus |
| Q52002244 | Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. |
| Q37533531 | Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow. |
| Q43672356 | Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine |
| Q36908997 | Modulating the vascular response to limb ischemia: angiogenic and cell therapies. |
| Q30537465 | Multifunctional in vivo vascular imaging using near-infrared II fluorescence |
| Q33410763 | Murine model of hindlimb ischemia |
| Q39258680 | NOx and ADMA changes with focal ischemia, amelioration with the chaperonin GroEL. |
| Q30582504 | Near-infrared II fluorescence for imaging hindlimb vessel regeneration with dynamic tissue perfusion measurement |
| Q35682213 | Nicotine and angiogenesis: a new paradigm for tobacco-related diseases. |
| Q44307941 | Nicotine promotes arteriogenesis |
| Q43658826 | Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis |
| Q44302091 | Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions |
| Q78057257 | Nitric oxide and angiogenesis |
| Q44484652 | Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women |
| Q41360752 | Nitric oxide synthase: role in the genesis of vascular disease |
| Q58816235 | Nonbone Marrow-Derived Circulating Progenitor Cells Contribute to Postnatal Neovascularization Following Tissue Ischemia |
| Q36377355 | Novel vascular molecule involved in monocyte adhesion to aortic endothelium in models of atherogenesis. |
| Q39819713 | Optimal ROS Signaling Is Critical for Nuclear Reprogramming. |
| Q46862730 | Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation. |
| Q30493459 | Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. |
| Q36645351 | Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats. |
| Q36410664 | PPARδ activation protects endothelial function in diabetic mice. |
| Q37668781 | Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN). |
| Q33916551 | Phytoestrogens and cardiovascular health. |
| Q43796150 | Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus |
| Q33915599 | Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. |
| Q35908085 | Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis |
| Q35179217 | Postgraduate training in vascular medicine: proposed requirements and standards. |
| Q43623823 | Propionyl-L-carnitine improves exercise performance and functional status in patients with claudication |
| Q28548045 | Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population |
| Q36993998 | Proton Pump Inhibitors Accelerate Endothelial Senescence |
| Q36067712 | Proton pump inhibitors and vascular function: A prospective cross-over pilot study |
| Q46139641 | Psychophysiological and cortisol responses to psychological stress in depressed and nondepressed older men and women with elevated cardiovascular disease risk |
| Q44961036 | Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy |
| Q30399678 | Rationale and design for PACE: patients with intermittent claudication injected with ALDH bright cells |
| Q83316553 | Re: The American "board" of vascular medicine: questions and concerns |
| Q43162047 | Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients |
| Q95528497 | Reply |
| Q86450699 | Response to Letter Regarding Article "Transdifferentiation of Human Fibroblasts to Endothelial Cells: Role of Innate Immunity" |
| Q42741425 | Response to letters regarding article, "unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine". |
| Q40300781 | Retinoic Acid Inducible Gene 1 Protein (RIG1)-Like Receptor Pathway Is Required for Efficient Nuclear Reprogramming |
| Q79746103 | SVMB presidential address. The time has come for vascular medicine |
| Q44604699 | Second hand smoke stimulates tumor angiogenesis and growth |
| Q35099756 | Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden. |
| Q38496540 | Sex differences in the prevalence of peripheral artery disease in patients undergoing coronary catheterization |
| Q44260673 | Short polymers of arginine rapidly translocate into vascular cells: effects on nitric oxide synthesis |
| Q79677855 | Should we measure asymmetric dimethylarginine in patients with coronary artery disease? |
| Q36636594 | Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature. |
| Q47711929 | State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association |
| Q43882419 | Statins have biphasic effects on angiogenesis |
| Q40405968 | Suboptimal intensity of risk factor modification in PAD. |
| Q33246409 | Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis |
| Q45040833 | T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease |
| Q36895779 | Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat |
| Q80518028 | Task force 11: training in vascular medicine and peripheral vascular catheter-based interventions endorsed by the Society for Cardiovascular Angiography and Interventions and the Society for Vascular Medicine |
| Q38939564 | The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity |
| Q48047827 | The Society for Vascular Medicine: the first quarter century |
| Q34140830 | The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model |
| Q35123800 | The emerging role of the thioredoxin system in angiogenesis |
| Q36964179 | The modulation of endothelial cell morphology, function, and survival using anisotropic nanofibrillar collagen scaffolds |
| Q72318109 | The role of coronary angiography and coronary revascularization before noncardiac vascular surgery |
| Q37127048 | The role of nicotine in the pathogenesis of atherosclerosis |
| Q38806531 | The use of machine learning for the identification of peripheral artery disease and future mortality risk |
| Q37127005 | Therapeutic transdifferentiation: a novel approach for vascular disease. |
| Q36844696 | Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia. |
| Q35126358 | Topical mecamylamine for diabetic macular edema |
| Q38746516 | Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation. |
| Q35022859 | Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity |
| Q34459333 | Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells |
| Q46175583 | Two cardiovascular risk factors in one? Homocysteine and its relation to glomerular filtration rate. A meta-analysis of 41 studies with 27,000 participants |
| Q35175641 | Two decades of progress in vascular medicine. |
| Q37336634 | Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. |
| Q82415086 | Vascular compliance versus flow-mediated vasodilation: correlation with cardiovascular risk factors |
| Q28655924 | Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature |
| Q67270847 | Vasoconstriction induced by ouabain in the canine coronary artery: contribution of adrenergic and nonadrenergic responses |
| Q34321203 | Walking impairment questionnaire improves mortality risk prediction models in a high-risk cohort independent of peripheral arterial disease status. |
| Q33503262 | nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis |
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