MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells

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MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1011909005
P356DOI10.1007/S00011-012-0438-6
P698PubMed publication ID22273691

P2093author name stringZhao Li
Guo-Xia Wang
Hong Zhuang
Zu-Jian Liang
Tian-Qi Yu
Huan-Tian Zhang
Bai-Dang Zhang
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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytesQ30931885
Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cellsQ33609716
MicroRNA-140 plays dual roles in both cartilage development and homeostasisQ33885698
The NF-kappaB inhibitor pyrrolidine dithiocarbamate blocks IL-1beta induced hyaluronan synthase 1 (HAS1) mRNA transcription, pointing at NF-kappaB dependence of the gene HAS1.Q34530267
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The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.Q53524092
Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage.Q54615798
Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathiesQ71339960
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Matrix metalloproteinases and aggrecanases cleave aggrecan in different zones of normal cartilage but colocalize in the development of osteoarthritic lesions in STR/ort miceQ74024195
Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritisQ79318170
Gene expression profiling of serum- and interleukin-1 beta-stimulated primary human adult articular chondrocytes--a molecular analysis based on chondrocytes isolated from one donorQ81849715
P433issue5
P304page(s)503-509
P577publication date2012-01-25
P1433published inInflammation ResearchQ1819367
P1476titleMiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells
P478volume61